Patents by Inventor Linda Clifford, legal representative

Linda Clifford, legal representative has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oligoamine compounds and derivatives thereof for cancer therapy
    Patent number: 7491849
    Abstract: Oligoamine compounds with anti-cancer and anti-proliferative activity are provided, as well as methods for making and using the compounds. The compounds are shown to be active against prostate cancer cell lines and against prostate cancer tumors in mice. The compounds are also useful in treatment of breast cancer and other cancers.
    Type: Grant
    Filed: October 1, 2004
    Date of Patent: February 17, 2009
    Assignee: Progen Pharmaceuticals, Inc.
    Inventors: Linda Clifford, legal representative, Aldonia L. Valasinas, Andrei V. Blokhin, Hirak S. Basu, Laurence J. Marton, Venodhar K. Reddy, Benjamin Frydman
  • Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
    Patent number: 7453011
    Abstract: Conformationally restricted polyamine compounds useful in treatment of cancer and other diseases marked by abnormal cell proliferation are disclosed. Improved methods of synthesizing such compounds are also disclosed. In one method of the invention, a carbene-bearing or carbene equivalent-bearing compound is reacted with the double bond of an alkene compound to form a cyclopropyl ring as the first step in the synthesis.
    Type: Grant
    Filed: June 4, 2007
    Date of Patent: November 18, 2008
    Assignee: Progen Pharmaceuticals, Inc.
    Inventors: Linda Clifford, legal representative, Aldonia L. Valasinas, Andrei V. Blokhin, Aparajita Sarkar, Hirak S. Basu, Venodhar K. Reddy, Laurence J. Marton, Yu Wang, Benjamin Frydman
  • Polyamine analog-amino acid conjugates useful as anticancer agents
    Patent number: 7312244
    Abstract: Conjugates in which polyamine analogs are conjugated to an amino acid are provided, as well as compositions comprising these conjugates. Methods of using these conjugates as anticancer treatments are also provided.
    Type: Grant
    Filed: November 8, 2001
    Date of Patent: December 25, 2007
    Assignee: Cellgate, Inc.
    Inventors: Linda Clifford, legal representative, Laurence J. Marton, Aldonia L. Valasinas, Venodhar K. Reddy, Benjamin Frydman, deceased
  • Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
    Patent number: 7279502
    Abstract: Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as prostate-specific antigen (PSA) and cathepsin B are provided, as well as compositions comprising these conjugates. Methods of using these conjugates in the treatment of prostate diseases are also provided.
    Type: Grant
    Filed: October 20, 2004
    Date of Patent: October 9, 2007
    Assignee: Cellgate, Inc.
    Inventors: Linda Clifford, legal representative, Laurence J. Marton, Benjamin Frydman, deceased