Patents by Inventor Lindsay S. Machan

Lindsay S. Machan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100010612
    Abstract: A stent balloon is provided with two conductive rings, created by a thin metallized coating deposited directly on the balloon, adjacent to the ends of the stent. The impedance between those rings and the body of the patient is measured at different AC frequencies. As the balloon approaches the vessel wall the impedance increases rapidly. Once the balloon forms full contact with vessel wall the impedance increases slowly. The changing impedance provides a guide for optimal apposition of the stent. The same conductive rings can also detect stent slippage and stent position relative to the balloon. With the addition of an extra conductive pad and wire, stent spring-back can be measured and corrected for.
    Type: Application
    Filed: July 9, 2008
    Publication date: January 14, 2010
    Inventors: Daniel Gelbart, Lindsay S. Machan
  • Publication number: 20090074830
    Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and taxol. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.
    Type: Application
    Filed: July 30, 2007
    Publication date: March 19, 2009
    Inventors: William L. HUNTER, Lindsay S. Machan, A. Larry Arsenault, Helen M. Burt, John K. Jackson, Stephen K. Dordunoo
  • Publication number: 20090036517
    Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.
    Type: Application
    Filed: April 4, 2008
    Publication date: February 5, 2009
    Applicant: ANGIOTECH PHARMACEUTICALS, INC.
    Inventors: William L. Hunter, Lindsay S. Machan, A. Larry Arsenault, Helen M. Burt, John K. Jackson, Stephen K. Dordunoo
  • Publication number: 20080166387
    Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and taxol. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.
    Type: Application
    Filed: July 30, 2007
    Publication date: July 10, 2008
    Inventors: William L. HUNTER, Lindsay S. MACHAN, A. Larry ARSENAULT, Helen M. BURT, John K. JACKSON, Stephen K. DORDUNOO
  • Patent number: 6846841
    Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: January 25, 2005
    Assignee: Angiotech Pharmaceuticals, Inc.
    Inventors: William L. Hunter, Lindsay S. Machan, A. Larry Arsenault
  • Publication number: 20040224023
    Abstract: The present invention provides methods for treating or preventing diseases associated with body passageways, comprising the step of delivering to an external portion of the body passageway a therapeutic agent. Representative examples of therapeutic agents include anti-angiogenic factors, anti-proliferative agents, anti-inflammatory agents, and antibiotics.
    Type: Application
    Filed: September 25, 2003
    Publication date: November 11, 2004
    Applicants: ANGIOTECH PHARMACEUTICALS, INC., THE UNIVERSITY OF BRITISH COLUMBIA
    Inventors: William L. Hunter, Lindsay S. Machan
  • Patent number: 6759431
    Abstract: The present invention provides methods for treating or preventing diseases associated with body passageways, comprising the step of delivering to an external portion of the body passageway a therapeutic agent. Representative examples of therapeutic agents include anti-angiogenic factors, anti-proliferative agents, anti-inflammatory agents, and antibiotics.
    Type: Grant
    Filed: August 20, 2001
    Date of Patent: July 6, 2004
    Assignees: Angiotech Pharmaceuticals, Inc., The University of British Columbia
    Inventors: William L. Hunter, Lindsay S. Machan
  • Publication number: 20040076672
    Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.
    Type: Application
    Filed: March 13, 2003
    Publication date: April 22, 2004
    Applicants: Angiotech Pharmaceuticals, Inc., University of British Columbia
    Inventors: William L. Hunter, Lindsay S. Machan, A. Larry Arsenault, Helen M. Burt, John K. Jackson, Stephen K. Dordunoo
  • Publication number: 20040062810
    Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.
    Type: Application
    Filed: March 14, 2003
    Publication date: April 1, 2004
    Applicant: Angiotech Pharmaceuticals, Inc.
    Inventors: William L. Hunter, Lindsay S. Machan, A. Larry Arsenault
  • Publication number: 20030203976
    Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.
    Type: Application
    Filed: June 7, 1995
    Publication date: October 30, 2003
    Inventors: WILLIAM L. HUNTER, LINDSAY S. MACHAN, A. LARRY ARSENAULT
  • Publication number: 20030124197
    Abstract: The present invention provides compositions and methods for improving the integrity of body passageways following surgery or injury. Representative examples of therapeutic agents include microtubule stabilizing agents, fibrosis inducers, angiogenic factors, growth factors and cytokines and other factors involved in the wound healing or fibrosis cascade.
    Type: Application
    Filed: December 18, 2002
    Publication date: July 3, 2003
    Applicant: University of British Columbia
    Inventors: Pierre E. Signore, Lindsay S. Machan
  • Patent number: 6544544
    Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.
    Type: Grant
    Filed: August 8, 2001
    Date of Patent: April 8, 2003
    Assignee: Angiotech Pharmaceuticals, Inc.
    Inventors: William L. Hunter, Lindsay S. Machan, A. Larry Arsenault
  • Patent number: 6506411
    Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also, provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.
    Type: Grant
    Filed: April 19, 1999
    Date of Patent: January 14, 2003
    Assignee: Angiotech Pharmaceuticals, Inc.
    Inventors: William L. Hunter, Lindsay S. Machan, A. Larry Arsenault
  • Publication number: 20030004209
    Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.
    Type: Application
    Filed: March 28, 2002
    Publication date: January 2, 2003
    Applicant: Angiotech Pharmaceuticals, Inc.
    Inventors: William L. Hunter, Lindsay S. Machan, A. Larry Arsenault
  • Publication number: 20030003094
    Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.
    Type: Application
    Filed: August 8, 2001
    Publication date: January 2, 2003
    Inventors: William L. Hunter, Lindsay S. Machan, A. Larry Arsenault
  • Publication number: 20020165265
    Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.
    Type: Application
    Filed: December 3, 1997
    Publication date: November 7, 2002
    Inventors: WILLIAM L. HUNTER, LINDSAY S. MACHAN, A. LARRY ARSENAULT
  • Publication number: 20020164377
    Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.
    Type: Application
    Filed: April 19, 1999
    Publication date: November 7, 2002
    Inventors: WILLIAM L HUNTER, LINDSAY S MACHAN, A LARRY ARSENAULT
  • Publication number: 20020119202
    Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.
    Type: Application
    Filed: August 9, 2001
    Publication date: August 29, 2002
    Inventors: William L. Hunter, Lindsay S. Machan, A. Larry Arsenault, Helen M. Burt, John K. Jackson, Stephen K. Dordunoo
  • Publication number: 20020065546
    Abstract: Stent grafts are provided comprising an endoluminal stent and a graft, wherein the stent graft releases an agent which induces the in vivo adhesion of the stent graft to vessel walls, or, otherwise induces or accelerates an in vivo fibrotic reaction causing said stent graft to adhere to vessel wall. Also provided are methods for making and using such stent grafts.
    Type: Application
    Filed: May 16, 2001
    Publication date: May 30, 2002
    Inventors: Lindsay S. Machan, John K. Jackson, William L. Hunter
  • Publication number: 20020052404
    Abstract: The present invention provides methods for treating or preventing diseases associated with body passageways, comprising the step of delivering to an external portion of the body passageway a therapeutic agent. Representative examples of therapeutic agents include anti-angiogenic factors, anti-proliferative agents, anti-inflammatory agents, and antibiotics.
    Type: Application
    Filed: August 20, 2001
    Publication date: May 2, 2002
    Inventors: William L. Hunter, Lindsay S. Machan