Abstract: This disclosure relates to scaffolds for inducing antibody responses against antigenic sites. In certain embodiments, this disclosure relates to compositions and methods using a filovirus sGP as a scaffold for inducing antibody responses against antigenic sites in foreign pathogens. In certain embodiments, this disclosure relates to compositions and methods using a filovirus sGP as a scaffold for inducing antibody responses against a virus to produce a viral vaccine.

Abstract: Disclosed is a testing device and method for a service life of an air-conditioning compressor of a new energy vehicle running with pure gas. The testing device includes an alternative refrigeration system, a measurement and control system, and a testing environment room. A main refrigeration cycle system of the alternative refrigeration system runs with pure gas, gas of a testing compressor is discharged via a discharge throttle valve, and then enters a suction end via a suction throttle valve and an electronic expansion valve, and since there is no phase change, a heat exchange amount is small; adjustable ranges of the discharge throttle valve, the suction throttle valve and the electronic expansion valve are wide; and based on the system structure, a small refrigeration system can be used to test a compressor having high cooling capacity, and the system can quickly achieve a target working condition with a small amount of refrigerant.

Abstract: The disclosure relates to a method, apparatus, readable medium, and electronic device for live stream interaction. The method includes: in accordance with displaying of a first control at a first target position of a live stream interface, obtaining a first duration during which a user watches the live stream interface; in accordance with a determination that the first duration is greater than or equal to a first predetermined duration threshold, switching the first control to a second control, and displaying the second control at a second target position of the live stream interface; and in response to a first operation command performed by the user on the second control, allocating a virtual resource to the user. In this way, interaction modes of a live stream room are enriched, and an activity level of the live stream room can be improved.

Abstract: The present disclosure relates to the technical field of multimedia, and in particular, to a control method and apparatus for multimedia content display, an electronic device, and a medium. First multimedia content is displayed on a first page; and in response to a terminal device changing in a preset attitude, the first page is switched to a second page, and second multimedia content is displayed on the second page. That is, the switching of the first page to the second page is implemented by triggering the attitude change of the terminal device, thereby improving the interestingness of user interaction.

Abstract: Disclosed herein are glass compositions that present several advantages over glasses and other materials currently used for redistribution layers for RF, interposers, and similar applications. The glasses disclosed herein are low cost, flat glasses that have high throughput for the laser damage and etching process used to create through glass vias (TGV). TGV generated using the silicate glasses and processes described herein have large waist diameters (Dw), which is a desirable feature with respect to producing glass articles such as interposers.

Abstract: The invention provides a Probiotic microcapsule and a preparation method thereof, relating to the technical field of Probiotic products. The method includes the following steps: (a) preparing a capsule core containing Probiotics: mixing the capsule core materials including Probiotic powder, microcrystalline cellulose and starch, then adding a hydroxypropyl methylcellulose solution thereinto, while mixing evenly, making the obtained mixture materials into spherical particulate capsule cores by the extrusion spherization method; (b) coating by atomization: coating the microcapsule cores with a coating material solution in a single layer or multiple layers by atomization, getting core-shell microcapsules. The Probiotic microcapsules prepared by the present invention have a large encapsulation, uniform microcapsule particles, controllable particle size, storage-resistance, targetability to intestinal tracts, resistance to gastric acids and high temperature stability.

Abstract: Disclosed are a cranial CT-based grading method and a corresponding system, which relate to the field of medical imaging. The cranial CT-based grading method as disclosed solves the problems of relatively great subjective disparities and poor operability in eye-balling ASPECTS assessment. The grading method includes: determining frames where target image slices are located from to-be-processed multi-frame cranial CT data; extracting target areas; performing infarct judgment on each target area included in the target areas to output an infarct judgment outcome regarding the target area; and outputting a grading outcome based on infarct judgment outcomes regarding all target areas.

Abstract: A textured glass article includes: a body comprising an aluminosilicate glass comprising greater than or equal to 16 wt % Al2O3, the body having at least a first surface; and a plurality of polyhedral surface features extending from the first surface, each of the plurality of polyhedral surface features comprising a base on the first surface, a plurality of facets extending from the first surface, and a surface feature size at the base greater than or equal to 10 ?m and less than or equal to 350 ?m, wherein the plurality of facets of each polyhedral surface feature converge toward one another.

Abstract: Provided are a method, apparatus and device for detecting a field curvature of a VR optical module, wherein a diaphragm is fixed on a lens of a camera, a first electronic control is used to drive the VR optical module to self-rotate around an optical axis of a VR lens, and a second electronic control is used to drive the camera to swing in a plane where the optical axis of the VR lens is located with a center of the diaphragm as a fixed point.

Abstract: The present invention provides a molecular marker C42257 for rapidly identifying genetic sex of Marsupenaeus japonicus and applications thereof. The nucleotide sequence of the molecular marker C42257 is shown in SEQ ID NO:1. The nucleotide sequences of the primer pair of molecular marker C42257 used for detection are C42257F: GGGGGACAA ACAGAGACA (SEQ ID NO: 2) and C42257R: ATCGGGGTGGATTTAGAA (SEQ ID NO: 3), respectively. The molecular marker C42257 is not affected by the tissue specificity of M. japonicus and the environment, and the steps are simple and the results are obvious. The genomic DNA of M. japonicus and the primer pair are subjected to PCR reaction and electrophoresis detection. If a target band appears at 183 bp, it is a female M. japonicus. The molecular marker can also promote the establishment of the seedling breeding technology of all-female or high-female-ratio M. japonicus. Therefore, it has a broad application prospect.

Abstract: Provided are a method, apparatus and device for detecting a field curvature of a VR optical module, wherein a diaphragm is fixed on a lens of a camera, a first electronic control is used to drive the VR optical module to self-rotate around an optical axis of a VR lens, and a second electronic control is used to drive the camera to swing in a plane where the optical axis of the VR lens is located with a center of the diaphragm as a fixed point.

Abstract: A vehicle includes a contactor electrically between a charge port and a traction battery, and a controller configured to maintain the contactor in a closed position until a charge current estimate, derived from vehicle load data without sensing current through the contactor or receiving data from a charge station regarding the current, is less than a predetermined threshold. The maintenance of the contactor position is responsive to a charge disconnect request.

Abstract: A method for screening a compound capable of regulating gene expression by binding to a transcription product particularly for obtaining a drug candidate compound. The method includes selecting a stem-loop structure as a desired motif in an RNA, inputting a parameter of a specific stem-loop structure, and executing a plurality of RNA higher-order structural analysis programs to search/extract a sequence that can assume the structure in a molecule thereof from an mRNA sequence, selecting a specific target sequence in a specific transcription product as an indicator of the position at which the stem-loop structure is present in the molecule in an mRNA having significance for development of a potential drug target in an object disease or the like from the extracted mRNA, designing/preparing a labeling probe on the basis of the sequence, performing screening using the labeling probe as an assessment system, and acquiring a low-molecular-weight compound that selectively stabilizes the stem-loop structure.

Abstract: A nucleic acid medicine for managing a disease or disorder related to unwanted gene expression. A technique for efficiently regulating gene expression in a cell using a relatively short oligonucleotide, by establishing a method for designing a nucleic acid medicine, that includes performing structural analysis based on sequence information of a target RNA sequence as an object for gene expression regulation, calculating the probability of existence of each structure from the results of the structural analysis and the energy of each structure, and calculating the existence probability in unified fashion of an endogenous stem-loop substructure, thereby specifying a more favorable endogenous stem-loop substructure. This technique can theoretically be applied to regulation expression of any gene, and is useful for treatment or prevention of various diseases and disorders.

Abstract: A vehicle includes a contactor electrically between a charge port and a traction battery, and a controller configured to maintain the contactor in a closed position until a charge current estimate, derived from vehicle load data without sensing current through the contactor or receiving data from a charge station regarding the current, is less than a predetermined threshold. The maintenance of the contactor position is responsive to a charge disconnect request.

Abstract: Provided are an aptamer having an inhibitory activity against NGF; a complex containing an aptamer having a binding activity or inhibitory activity against NGF and a functional substance (e.g., affinity substances, labeling substances, enzymes, drug delivery vehicles, drugs and the like); a medicament, a diagnostic agent, a labeling agent and the like containing an aptamer having a binding activity or inhibitory activity against NGF, or a complex containing the aptamer and the functional substance; and the like.

Abstract: Provided by the present invention are an aptamer having an inhibitory activity on FGF2; a complex containing an aptamer having a binding activity or an inhibitory activity on FGF2, and a functional substance (e.g., affinity substance, labeling substance, enzyme, drug delivery vehicle, or drug and the like); a medicament, diagnostic reagent or labeling agent containing an aptamer having a binding activity or an inhibitory activity on FGF2, or a complex containing said aptamer and a functional substance; and the like.

Abstract: Provided by the present invention are an aptamer having an inhibitory activity on FGF2; a complex containing an aptamer having a binding activity or an inhibitory activity on FGF2, and a functional substance (e.g., affinity substance, labeling substance, enzyme, drug delivery vehicle, or drug and the like); a medicament, diagnostic reagent or labeling agent containing an aptamer having a binding activity or an inhibitory activity on FGF2, or a complex containing said aptamer and a functional substance; and the like.

Abstract: The present invention provides an aptamer binding to NGF and capable of forming a potential secondary structure represented by the formula (I): wherein N is one nucleotide selected from the group consisting of A, G, C, U and T, N11-N13, N21-N23, N32-N38 and N42-N48 are the same or different and each is a bond or 1 or 2 nucleotides selected from the group consisting of A, G, C, U and T, N14, N24, N31, N41, N39 and N49 are the same or different and each is one nucleotide selected from the group consisting of A, G, C, U and T, N14 and N24, N31 and N41, and N39 and N49 each form a Watson-Crick base pair, N11-N12-N13-N14 and N21-N22-N23-N24 are nucleotide sequences capable of forming a stem structure in combination, and N31-N32-N33-N34-N35-N36-N37-N38-N39 and N41-N42-N43-N44-N45-N46-N47-N48-N49 are nucleotide sequences capable of forming a stem structure in combination.

Abstract: A method and apparatus provide live call text-to-speech. The method can include entering an ongoing voice call at a first communication device with a second communication device. The method can include receiving text input at the first communication device during the ongoing voice call. The method can include converting the text input to speech during the ongoing voice call to generate a text-to-speech audible signal. The method can include sending the text-to-speech audible signal from the first communication device to the second communication device during the ongoing voice call.