Abstract: A radiation therapy system is disclosed. The radiation therapy system includes a gantry, a first radiation source, and a second radiation source. The gantry is configured to have a cavity extending in a direction along a rotation axis, and the cavity is configured to house a target object. The first radiation source is mounted on the gantry, and configured to emit a treatment beam to a treatment area of the target object. The second radiation source is mounted on the gantry, and configured to emit an imaging beam to an imaging area of the target object. The treatment area partially overlaps the imaging area. A rotation plane of the first radiation source and a rotation plane of the second radiation source are distributed in a direction along the rotation axis.

Abstract: A business intelligence (BI) server is described that supports data and schemas stored in multiple languages. The BI server implements a lookup table and lookup function that allows users to work with queries in different languages. When the user logs in, a session object is created for the user, which maintains the state information. A session variable specifies the language currently being used by the user. The BI server can inspect this session variable to determine the language of the user and perform the lookup translations as necessary. For example, if the language used by the session is different from the language of the base table storing the necessary information, the BI server can perform a translation by invoking a lookup function. The execution of the lookup can include performing a join operation of the base table with the lookup table to yield a translated value requested by the query.

Abstract: The present invention relates to a fluorescent probe for detecting nitroreductase and a preparation method and use thereof in enzymatic reactions, belonging to the field of industrial analysis and detection. The fluorescent probe is 3-(4-(2-(4?-(diphenylamino)-3-((4-nitrobenzyl)oxy)-[1, 1?-biphenyl]-4-yl)vinyl)quinolin-1-ium-1-yl)propane-1-sulfonate. The fluorescent probe of the present invention, with the introduction of hydrophilic groups, sulfonate and quinolinium, the probe's hydrophilicity is enhanced, under the enzymatic catalysis of nitroreductase (NTR), 1,6-rearrangement and elimination reaction occurs, and hydroxyl group is generated. Detection and analysis of the NTR in the industrial enzymatic reactions can be realized due to the change of fluorescence which is induced by the intramolecular charge transfer (ICT) effect.

Abstract: The present invention relates to a fluorescent probe for detecting nitroreductase and a preparation method and use thereof in enzymatic reactions, belonging to the field of industrial analysis and detection. The fluorescent probe is 3-(4-(2-(4?-(diphenylamino)-3-((4-nitrobenzyl)oxy)-[1,1?-biphenyl]-4-yl)vinyl)quinolin-1-ium-1-yl)propane-1-sulfonate. The fluorescent probe of the present invention, with the introduction of hydrophilic groups, sulfonate and quinolinium, the probe's hydrophilicity is enhanced, under the enzymatic catalysis of nitroreductase (NTR), 1,6-rearrangement and elimination reaction occurs, and hydroxyl group is generated. Detection and analysis of the NTR in the industrial enzymatic reactions can be realized due to the change of fluorescence which is induced by the intramolecular charge transfer (ICT) effect.

Abstract: The present invention includes compositions and methods for enhancing Th1/Th17 cell responses and decreasing Th2 cell responses. In various embodiments the present invention describes activation of human dendritic cells and enhancement of antigen-specific T cell responses in a Dectin-1-expressing human dendritic cells comprising an anti-Dectin-1-specific antibody or fragment thereof fused with one or more antigens. TLR2 ligands may also be included to enhance the activation and for enhancement of T-cell responses. Further, the invention also includes methods based on the compositions described herein for the treatment of allergy, and asthma.

Abstract: Compositions and methods for enhancing Th1/Th17 cell responses and decreasing Th2 cell responses are disclosed herein. In various embodiments the present invention describes activation of human dendritic cells and enhancement of antigen-specific T cell responses in a Dectin-1-expressing human dendritic cells comprising an anti-Dectin-1-specific antibody or fragment thereof fused with one or more antigens. TLR2 ligands may also be included to enhance the activation and for enhancement of T-cell responses. Further, the invention also includes methods based on the compositions described herein for the treatment of pathogenic infections.

Abstract: The present invention includes compositions and methods for binding Dectin-1 on immune cells with anti-Dectin-1-specific antibodies or fragment thereof capable of activating the immune cells.

Abstract: A business intelligence (BI) server and repository are described which support a set of customized and/or calculated data members. In accordance with an embodiment, the BI server maintains a connection to a plurality of data sources which may store a set of dimension members. The data source can be relational, file storage based, multidimensional and other types. In accordance with an embodiment, the BI server can accept queries from the user that contain calculated members as a parameter. The calculated member is defined by an expression including multiple dimension members and one or more arithmetic operators. The BI server can parse and validate the query and rewrite the query for the data source. After the query is rewritten and optimized, it is executed against the data source and a set of results is received.

Abstract: The present invention includes compositions and methods for enhancing Th1/Th17 cell responses and decreasing Th2 cell responses. In various embodiments the present invention describes activation of human dendritic cells and enhancement of antigen-specific T cell responses in a Dectin-1-expressing human dendritic cells comprising an anti-Dectin-1-specific antibody or fragment thereof fused with one or more antigens. TLR2 ligands may also be included to enhance the activation and for enhancement of T-cell responses. Further, the invention also includes methods based on the compositions described herein for the treatment of allergy, and asthma.

Abstract: A business intelligence (BI) server and repository are described which support a set of hierarchical relationships among the data. The BI server receives user input specifying a set of parent-child or other ancestral relationship among a set of data in a data source. The BI server generates a set of SQL queries and executes the queries to pre-populate a set of tables which specify the parent child relationships among the data in the data source. One such table is a parent-child relationship closure table that defines the inter-member relationships among the data members. Once the tables are populated, the BI server uses the closure tables to answer queries that require knowledge of the ancestral relationships among data.

Abstract: Compositions and methods for enhancing Th1/Th17 cell responses and decreasing Th2 cell responses are disclosed herein. In various embodiments the present invention describes activation of human dendritic cells and enhancement of antigen-specific T cell responses in a Dectin-1-expressing human dendritic cells comprising an anti-Dectin-1-specific antibody or fragment thereof fused with one or more antigens. TLR2 ligands may also be included to enhance the activation and for enhancement of T-cell responses. Further, the invention also includes methods based on the compositions described herein for the treatment of pathogenic infections.

Abstract: A business intelligence (BI) server and repository are described which support a set of customized and/or calculated data members. In accordance with an embodiment, the BI server maintains a connection to a plurality of data sources which may store a set of dimension members. The data source can be relational, file storage based, multidimensional and other types. In accordance with an embodiment, the BI server can accept queries from the user that contain calculated members as a parameter. The calculated member is defined by an expression including multiple dimension members and one or more arithmetic operators. The BI server can parse and validate the query and rewrite the query for the data source. After the query is rewritten and optimized, it is executed against the data source and a set of results is received.

Abstract: A business intelligence (BI) server is described that supports data and schemas stored in multiple languages. The BI server implements a lookup table and lookup function that allows users to work with queries in different languages. When the user logs in, a session object is created for the user, which maintains the state information. A session variable specifies the language currently being used by the user. The BI server can inspect this session variable to determine the language of the user and perform the lookup translations as necessary. For example, if the language used by the session is different from the language of the base table storing the necessary information, the BI server can perform a translation by invoking a lookup function. The execution of the lookup can include performing a join operation of the base table with the lookup table to yield a translated value requested by the query.

Abstract: A business intelligence (BI) server and repository are described which support a set of hierarchical relationships among the data. The BI server receives user input specifying a set of parent-child or other ancestral relationship among a set of data in a data source. The BI server generates a set of SQL queries and executes the queries to pre-populate a set of tables which specify the parent child relationships among the data in the data source. One such table is a parent-child relationship closure table that defines the inter-member relationships among the data members. Once the tables are populated, the BI server uses the closure tables to answer queries that require knowledge of the ancestral relationships among data.

Abstract: The present invention includes compositions and methods for binding Dectin-1 on immune cells with anti-Dectin-1-specific antibodies or fragment thereof capable of activating the immune cells.