Abstract: Provided is an oral Pt(IV) anticancer prodrug containing a 3-bromopyruvate as an axial ligand, with a molecular formula of cis,trans,cis-[Pt(1R,2R-diaminocyclohexane)(OH)(3-bromopyruvate)(C2O4)]. It is a prodrug of oxaliplatin and 3-bromopyruvic acid is a small molecular glycolysis inhibitor. The prodrug is able to simultaneously act on DNA replication and glycolytic pathways of cancer cells, giving full play to the advantage of double-acting targets. The oral Pt(IV) anticancer prodrug is synthesized by using oxaliplatin as a starting material, performing axial oxidation with H2O2 and neutralizing the oxidized product with 3-bromopyruvic acid.

Abstract: The present invention relates to new double stranded RNA (dsRNA) structures and their use in gene silencing.

Abstract: The present invention relates to new double stranded RNA (dsRNA) structures and their use in gene silencing.

Abstract: Embodiments of the present invention disclose an information processing method. A first base station receives a handover request message from a second base station. The first base station determines whether the handover request message is an initial handover request message directly sent by a source base station in a handover process or a forwarded handover request message. If a judging result is that the handover request message is the forwarded handover request message, the first base station saves a user equipment, context in the handover request message so as to become a prepared base station of the UE.

Abstract: A load sharing method, device, and system are disclosed. A first base station obtains a current load of the first base station. The first base station is connected to a mobility management entity (MME). The first base station selects a second base station that is also connected to the MME when the current load of the first base station exceeds a preset load threshold. Information of a load to be shared from the first base station to the second base station is transmitted so that the load to be shared can be shared with the second base station without switching a user equipment (UE) served by the first base station to the second base station.

Abstract: A load sharing method, device, and system are provided in the disclosure. The method includes obtaining a current load value. If the current load value exceeds a preset load threshold value, a sharing base station is selected. Information of a shared load that needs to be shared is transmitted to the selected sharing base station.

Abstract: A load sharing method, device, and system are provided in the disclosure. The method includes obtaining a current load value. If the current load value exceeds a preset load threshold value, a sharing base station is selected. Information of a shared load that needs to be shared is transmitted to the selected sharing base station.