Patents by Inventor Lingyan Wang
Lingyan Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240030663Abstract: The present application discloses a tool-free mounting structure for a fan connector. The mounting structure includes a fan frame and a fan connector, the fan connector including a male connector and a female connector, a front side wall of the fan frame being provided with a first avoiding hole, and a front end of the female connector extending to a front side of the fan frame through the first avoiding hole. A rear end of the female connector is provided with a limiting structure, the female connector is provided with a first limiting column, the front side wall of the fan frame is sandwiched between the first limiting column and the limiting structure, and the front side wall of the fan frame is provided with a second avoiding hole configured to allow the first limiting column to pass through.Type: ApplicationFiled: December 30, 2021Publication date: January 25, 2024Inventors: Tao LIU, Lesen ZHAO, Lingyan WANG, Xuejun TENG, Yonghao MA
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Patent number: 11667906Abstract: Magnetic microcarrier beads have a particle size of 1 to 1000 micrometers and include a composite core and a polymer coating that surrounds and encapsulates the core. The composite core includes magnetic particles embedded within an indigestible polymer matrix. The coating is a digestible or indigestible polymer that facilitates cell adhesion to the surface of the beads during cell culture. Magnetic force can be used to agitate the microcarrier beads during cell culture as well as to separate the beads from cultured cells or processed bio-media.Type: GrantFiled: November 24, 2015Date of Patent: June 6, 2023Assignee: CORNING INCORPORATEDInventors: Stephen Joseph Caracci, Ye Fang, Ann MeeJin Ferrie, Yan Jin, Lingyan Wang, Yue Zhou
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Publication number: 20230048175Abstract: A method for forming a treated sintered composition includes: providing a slurry precursor including a lithium-, sodium-, or magnesium-based compound; tape casting the slurry precursor to form a green tape; sintering the green tape at a temperature in a range of 500° C. to 1350° C. for a time in a range of less than 60 min to form a sintered composition; and heat treating the sintered composition at a temperature in a range of 700° C. to 1100° C. for a time in a range of 1 min to 2 hrs in an oxygen-containing atmosphere to form the treated sintered composition.Type: ApplicationFiled: July 30, 2021Publication date: February 16, 2023Inventors: Cameron Wayne Tanner, Elizabeth Marie Vileno, Lingyan Wang
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Patent number: 11505501Abstract: A method for forming a sintered composition including providing a slurry precursor including a lithium-, sodium-, or magnesium-based compound; tape casting the slurry precursor to form a green tape; and sintering the green tape at a temperature in a range of 500° C. to 1350° C. for a time in a range of less than 60 min to form a sintered composition, such that the slurry precursor further includes a solvent and dispersant. The dispersant may include an amine compound, a carboxylic acid compound, or combinations, mixtures, or salts thereof.Type: GrantFiled: August 20, 2021Date of Patent: November 22, 2022Assignee: CORNING INCORPORATEDInventors: Yvonne Marie Burton, Yinghong Chen, Bethany Rose Conway, Josiah M Lorenzo, Cameron Wayne Tanner, Lingyan Wang
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Publication number: 20190326039Abstract: Magnetic particles have a particle size of 500 nm of less and include a core and a polymer coating that surrounds and encapsulates the core. The core includes a metal, metal alloy, or metal oxide of at least one metal such as B, Mg, Al, Mn, Co, Ni, Cu, Fe Sm, Ln, Yb, Dy, Gd or Er and Nb. The magnetic core is polycrystalline particles which are superspin glass magnetic materials having coercivity greater than zero and magnetic remenance greater than zero at room temperature. Magnetic moment of these superspin glass magnetic materials at low field show increasing with temperature over room temperature. An in situ hydrolysis/precipitation method from precursor metal salts is used to form the polymer-encapsulated magnetic particles.Type: ApplicationFiled: April 23, 2019Publication date: October 24, 2019Inventors: Ann MeeJin Ferrie, Yan Jin, Lingyan Wang, Yue Zhou
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Patent number: 10393690Abstract: A flexible chemiresistor (CR) sensor for sensing a molecule of interest in a fluid (liquid or gas) is provided. The flexible CR sensor comprises a flexible chemiresistor (CR) module. The flexible CR module comprises a flexible substrate such polyethylene terephthalate (PET), polyethylene naphthalate (PEN) or polyimide (PI), and a thin film nanoparticle assembly assembled on the flexible substrate. The thin film nanoparticle assembly comprises metal or metal alloy core, ligand-capped nanoparticles and molecular linkers connecting the nanoparticles. The flexible CR sensor and an intelligent pattern recognition engine can be incorporated in a handheld device that can detect a molecule of interest in a fluid (e.g., a liquid or gas) accurately, rapidly, and without false positives. Any sensing array nanomaterial, pattern recognition, and compact/or electronic hardware can be integrated to achieve a desired detection limit and response speed.Type: GrantFiled: April 21, 2017Date of Patent: August 27, 2019Assignee: The Research Foundation of State University of New YorkInventors: Chuan-Jian Zhong, Jin Luo, Lingyan Wang
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Patent number: 10319502Abstract: Magnetic particles (100) have a particle size (134) of 500 nm or less and include a core (110) and a polymer coating (120) that surrounds and encapsulates the core (110). The core (110) includes a metal, metal alloy, or metal oxide of at least one metal such as B, Mg, Al, Mn, Co, Ni, Cu, Fe Sm, Yb, Dy, Gd or Er and Nb. The magnetic core (100) is a polycrystalline particle and is a superspin glass magnetic material, having a coercivity greater than zero and a magnetic remenance greater than zero at room temperature. Above room temperature and at low field, the magnetic moment of these superspin glass magnetic materials increases with temperature. An in situ hydrolysis/precipitation method from precursor metal salts is used to form the polymer-encapsulated magnetic particles (100).Type: GrantFiled: October 23, 2015Date of Patent: June 11, 2019Assignee: Corning IncorporatedInventors: Ann MeeJin Ferrie, Yan Jin, Lingyan Wang, Yue Zhou
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Patent number: 10011503Abstract: Methods for making activated carbon-supported transition metal-based nanoparticles include (a) impregnated activated carbon with at least one transition metal-containing compound, and (b) heating the impregnated activated carbon at a temperature and for a time sufficient to carbothermally reduce the transition metal-containing compound. Also disclosed are activated carbon-supported transition metal-based nanoparticles produced by such methods. Further disclosed are methods for treating water and waste streams that include contacting the water or waste streams with the activated carbon-supported transition metal-based nanoparticles.Type: GrantFiled: July 22, 2014Date of Patent: July 3, 2018Assignee: CORNING INCORPORATEDInventors: William Peter Addiego, Benedict Yorke Johnson, Lingyan Wang
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Publication number: 20180151278Abstract: Magnetic particles (100) have a particle size (134) of 500 nm or less and include a core (110) and a polymer coating (120) that surrounds and encapsulates the core (110). The core (110) includes a metal, metal alloy, or metal oxide of at least one metal such as B, Mg, Al, Mn, Co, Ni, Cu, Fe Sm, Yb, Dy, Gd or Er and Nb. The magnetic core (100) is a polycrystalline particle and is a superspin glass magnetic material, having a coercivity greater than zero and a magnetic remenance greater than zero at room temperature. Above room temperature and at low field, the magnetic moment of these superspin glass magnetic materials increases with temperature. An in situ hydrolysis/precipitation method from precursor metal salts is used to form the polymer-encapsulated magnetic particles (100).Type: ApplicationFiled: October 23, 2015Publication date: May 31, 2018Inventors: Ann MeeJin Ferrie, Yan Jin, Lingyan Wang, Yue Zhou
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Publication number: 20180036296Abstract: Novel benzamide compounds including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives having activity against mammalian factor Xa are described. Compositions containing such compounds are also described. The compounds and compositions are useful in vitro or in vivo for preventing or treating coagulation disorders.Type: ApplicationFiled: March 22, 2017Publication date: February 8, 2018Inventors: Bing-Yan Zhu, Penglie Zhang, Lingyan Wang, Wenrong Huang, Erick A. Goldman, Wenhao Li, Jingmei Zuckett, Yonghong Song, Robert M. Scarborough
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Publication number: 20170284953Abstract: A flexible chemiresistor (CR) sensor for sensing a molecule of interest in a fluid (liquid or gas) is provided. The flexible CR sensor comprises a flexible chemiresistor (CR) module. The flexible CR module comprises a flexible substrate such polyethylene terephthalate (PET), polyethylene naphthalate (PEN) or polyimide (PI), and a thin film nanoparticle assembly assembled on the flexible substrate. The thin film nanoparticle assembly comprises metal or metal alloy core, ligand-capped nanoparticles and molecular linkers connecting the nanoparticles. The flexible CR sensor and an intelligent pattern recognition engine can be incorporated in a handheld device that can detect a molecule of interest in a fluid (e.g., a liquid or gas) accurately, rapidly, and without false positives. Any sensing array nanomaterial, pattern recognition, and compact/or electronic hardware can be integrated to achieve a desired detection limit and response speed.Type: ApplicationFiled: April 21, 2017Publication date: October 5, 2017Inventors: Chuan-Jian Zhong, Jin Luo, Lingyan Wang
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Patent number: 9776891Abstract: A liquid filter article, including: a housing having an inlet, an outlet, and an adsorbent bed there between, the bed comprising: a first stage having a first adsorbent, the first adsorbent including an activated carbon honeycomb infused with a plurality of zero valent iron nanoparticles (“Fe-AC”); and a second stage having a second adsorbent, the second adsorbent being selected from iron oxide particles supported on activated carbon honeycomb (“FEOX-AC”), iron oxide particles supported on activated alumina honeycomb (“FeOX-AA”), or a combination thereof, wherein the first stage is in fluid communication with the second stage. Also disclosed is a method of using the liquid filter article to remediate heavy metals in water.Type: GrantFiled: July 21, 2015Date of Patent: October 3, 2017Assignee: Corning IncorporatedInventors: William Peter Addiego, Benedict Yorke Johnson, Lingyan Wang
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Patent number: 9732111Abstract: The present invention relates to 2?-Alkynyl Substituted Nucleoside Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein B, X, R1, R2, R3 and R4 are as defined herein. The present invention also relates to compositions comprising at least one 2?-Alkynyl Substituted Nucleoside Derivative, and methods of using the 2?-Alkynyl Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.Type: GrantFiled: November 14, 2013Date of Patent: August 15, 2017Assignee: Merck Sharp & Dohme Corp.Inventors: Frank Bennett, Yuhua Huang, Lingyan Wang, Stephane L. Bogen, Angela D. Kerekes, Vinay M. Girijavallabhan, Gabor Butora, Quang Truong, Ian Davies, Ann E. Weber
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Patent number: 9632050Abstract: A flexible chemiresistor (CR) sensor for sensing a molecule of interest in a fluid (liquid or gas) is provided. The flexible CR sensor comprises a flexible chemiresistor (CR) module. The flexible CR module comprises a flexible substrate such polyethylene terephthalate (PET), polyethylene naphthalate (PEN) or polyimide (PI), and a thin film nanoparticle assembly assembled on the flexible substrate. The thin film nanoparticle assembly comprises metal or metal alloy core, ligand-capped nanoparticles and molecular linkers connecting the nanoparticles. The flexible CR sensor and an intelligent pattern recognition engine can be incorporated in a handheld device that can detect a molecule of interest in a fluid (e.g., a liquid or gas) accurately, rapidly, and without false positives. Any sensing array nanomaterial, pattern recognition, and compact/or electronic hardware can be integrated to achieve a desired detection limit and response speed.Type: GrantFiled: July 13, 2015Date of Patent: April 25, 2017Assignee: The Research Foundation for State University of New YorkInventors: Chuan-Jian Zhong, Jin Luo, Lingyan Wang
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Patent number: 9610561Abstract: A method of making a filter article having a honeycomb substrate having adsorbent filled channels, including: sealing the first end of a porous, cellular honeycomb substrate; filling the channels of the cellular honeycomb substrate with a dry adsorbent source material; sealing the second end of the filled honeycomb to form a sealed honeycomb; contacting the sealed honeycomb and water for a time sufficient to convert the dry precursor material in-situ to a paste; removing the seals from the first and second ends; and heating the contacted honeycomb to convert the paste to an adsorbent. Also disclosed is a filter article having a honeycomb substrate having adsorbent filled channels and methods of using the article.Type: GrantFiled: July 27, 2015Date of Patent: April 4, 2017Assignee: Corning IncorporatedInventors: William Peter Addiego, Benedict Yorke Johnson, Lingyan Wang
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Publication number: 20160317511Abstract: Novel benzamide compounds including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives having activity against mammalian factor Xa are described. Compositions containing such compounds are also described. The compounds and compositions are useful in vitro or in vivo for preventing or treating coagulation disorders.Type: ApplicationFiled: June 17, 2015Publication date: November 3, 2016Inventors: Bing-Yan Zhu, Penglie Zhang, Lingyan Wang, Wenrong Huang, Erick A. Goldman, Wenhao Li, Jingmei Zuckett, Yonghong Song, Robert M. Scarborough
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Patent number: 9416129Abstract: In its many embodiments, the present invention provides certain iminothiazine dioxide compounds, including compounds Formula (I): (I) and tautomers and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds, said tautomers and said stereoisomers, wherein the middle ring (referred to herein as “ring B”) of the tricyclic substituent is an optionally substituted 6-membered ring, and each of the remaining variables shown in the formula are as defined herein. The novel compounds of the invention are useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including Alzheimer's disease, are also disclosed.Type: GrantFiled: October 14, 2013Date of Patent: August 16, 2016Assignee: Merck Sharp & Dohme Corp.Inventors: Eric J. Gilbert, Jared N. Cumming, Andrew W. Stamford, Younong Yu, Jack D. Scott, Ulrich Iserloh, Lingyan Wang, John P. Caldwell
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Publication number: 20160145600Abstract: Magnetic microcarrier beads have a particle size of 1 to 1000 micrometers and include a composite core and a polymer coating that surrounds and encapsulates the core. The composite core includes magnetic particles embedded within an indigestible polymer matrix. The coating is a digestible or indigestible polymer that facilitates cell adhesion to the surface of the beads during cell culture. Magnetic force can be used to agitate the microcarrier beads during cell culture as well as to separate the beads from cultured cells or processed bio-media.Type: ApplicationFiled: November 24, 2015Publication date: May 26, 2016Inventors: Stephen Joseph Caracci, Ye Fang, Ann MeeJin Ferrie, Yan Jin, Lingyan Wang, Yue Zhou
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Publication number: 20160038915Abstract: A method of making a filter article having a honeycomb substrate having adsorbent filled channels, including: sealing the first end of a porous, cellular honeycomb substrate; filling the channels of the cellular honeycomb substrate with a dry adsorbent source material; sealing the second end of the filled honeycomb to form a sealed honeycomb; contacting the sealed honeycomb and water for a time sufficient to convert the dry precursor material in-situ to a paste; removing the seals from the first and second ends; and heating the contacted honeycomb to convert the paste to an adsorbent. Also disclosed is a filter article having a honeycomb substrate having adsorbent filled channels and methods of using the article.Type: ApplicationFiled: July 27, 2015Publication date: February 11, 2016Inventors: William Peter Addiego, Benedict Yorke Johnson, Lingyan Wang
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Publication number: 20160023921Abstract: Methods for making activated carbon-supported transition metal-based nanoparticles include (a) impregnated activated carbon with at least one transition metal-containing compound, and (b) heating the impregnated activated carbon at a temperature and for a time sufficient to carbothermally reduce the transition metal-containing compound. Also disclosed are activated carbon-supported transition metal-based nanoparticles produced by such methods. Further disclosed are methods for treating water and waste streams that include contacting the water or waste streams with the activated carbon-supported transition metal-based nanoparticles.Type: ApplicationFiled: July 22, 2014Publication date: January 28, 2016Inventors: William Peter Addiego, Benedict Yorke Johnson, Lingyan Wang