Patents by Inventor Liping Lin
Liping Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200063922Abstract: A light bulb apparatus has a plurality of LED modules, a substrate, a driver circuit board, a plastic piece, a radiator and a lamp cap. The substrate has aluminum material for mounting the plurality of LED modules, a first connection end and a second connection end. The first connection end and the second connection end are electrically connected to the plurality of LED modules. The plastic piece with a guiding groove is used for inserting the driver circuit board. The radiator has a top plate and a side wall. The substrate is fixed on the top plate, and the side wall are connected to the plastic piece.Type: ApplicationFiled: October 31, 2019Publication date: February 27, 2020Inventors: Qiyuan Wang, Yunnan Lin, Liping Lin
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Publication number: 20200031807Abstract: Disclosed are a small-molecule AURKB inhibitor and applications thereof. The invention is directed to a diindolylmethane compound of formula (I) or a stereoisomer, a tautomer, a solvate, a prodrug, a N-oxide or a pharmaceutically acceptable salt thereof. The invention also provides an application of the small-molecule inhibitor and a modified derivative thereof (such as a stereoisomer, a tautomer, a solvate, a prodrug, an N-oxide or a pharmaceutically acceptable salt) in the preparation of an antitumor drug. The small-molecule AURKB inhibitor identified herein is slightly toxic to those normal cells and can significantly inhibit the expression of a downstream gene E2F2 mediated in the phosphorylation of an AURKB substrate histone H3S10. Therefore, the small-molecule inhibitor, as an anti-tumor drug, can effectively inhibit the proliferation of various tumor cells and induce the apoptosis of tumor cells.Type: ApplicationFiled: May 10, 2019Publication date: January 30, 2020Inventors: Quan ZHAO, Renxiang TAN, Yadong WANG, Liping LIN
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Patent number: 10495265Abstract: A light bulb apparatus has a plurality of LED modules, a substrate, a driver circuit board, a plastic piece, a radiator and a lamp cap. The substrate has aluminum material for mounting the plurality of LED modules, a first connection end and a second connection end. The first connection end and the second connection end are electrically connected to the plurality of LED modules. The plastic piece with a guiding groove is used for inserting the driver circuit board. The radiator has a top plate and a side wall. The substrate is fixed on the top plate, and the side wall are connected to the plastic piece.Type: GrantFiled: June 18, 2019Date of Patent: December 3, 2019Assignee: XIAMEN ECO LIGHTING CO. LTD.Inventors: Qiyuan Wang, Yunnan Lin, Liping Lin
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Publication number: 20190301685Abstract: A light bulb apparatus has a plurality of LED modules, a substrate, a driver circuit board, a plastic piece, a radiator and a lamp cap. The substrate has aluminum material for mounting the plurality of LED modules, a first connection end and a second connection end. The first connection end and the second connection end are electrically connected to the plurality of LED modules. The plastic piece with a guiding groove is used for inserting the driver circuit board. The radiator has a top plate and a side wall. The substrate is fixed on the top plate, and the side wall are connected to the plastic piece.Type: ApplicationFiled: June 18, 2019Publication date: October 3, 2019Inventors: Qiyuan Wang, Yunnan Lin, Liping Lin
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Patent number: 10364943Abstract: A light bulb apparatus has a plurality of LED modules, a substrate, a driver circuit board, a plastic piece, a radiator and a lamp cap. The substrate has aluminum material for mounting the plurality of LED modules, a first connection end and a second connection end. The first connection end and the second connection end is electrically connected to the plurality of LED modules. The plastic piece with a guiding groove is used for inserting the driver circuit board. The radiator has a top plate and a side wall. The substrate is fixed on the top plate, and the side wall are connected to the plastic piece.Type: GrantFiled: January 22, 2019Date of Patent: July 30, 2019Assignee: XIAMEN ECO LIGHTING CO. LTD.Inventors: Qiyuan Wang, Yunnan Lin, Liping Lin
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Publication number: 20190154208Abstract: A light bulb apparatus has a plurality of LED modules, a substrate, a driver circuit board, a plastic piece, a radiator and a lamp cap. The substrate has aluminum material for mounting the plurality of LED modules, a first connection end and a second connection end. The first connection end and the second connection end is electrically connected to the plurality of LED modules. The plastic piece with a guiding groove is used for inserting the driver circuit board. The radiator has a top plate and a side wall. The substrate is fixed on the top plate, and the side wall are connected to the plastic piece.Type: ApplicationFiled: January 22, 2019Publication date: May 23, 2019Inventors: Qiyuan Wang, Yunnan Lin, Liping Lin
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Patent number: 10222003Abstract: A light bulb apparatus has a plurality of LED modules, a substrate, a driver circuit board, a plastic piece, a radiator and a lamp cap. The substrate has aluminum material for mounting the plurality of LED modules, a first connection end and a second connection end. The first connection end and the second connection end is electrically connected to the plurality of LED modules. The plastic piece with a guiding groove is used for inserting the driver circuit board. The radiator has a top plate and a side wall. The substrate is fixed on the top plate, and the side wall are connected to the plastic piece.Type: GrantFiled: September 10, 2018Date of Patent: March 5, 2019Assignee: XIAMEN ECO LIGHTING CO. LTD.Inventors: Qiyuan Wang, Yunnan Lin, Liping Lin
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Publication number: 20190003655Abstract: A light bulb apparatus has a plurality of LED modules, a substrate, a driver circuit board, a plastic piece, a radiator and a lamp cap. The substrate has aluminum material for mounting the plurality of LED modules, a first connection end and a second connection end. The first connection end and the second connection end is electrically connected to the plurality of LED modules. The plastic piece with a guiding groove is used for inserting the driver circuit board. The radiator has a top plate and a side wall. The substrate is fixed on the top plate, and the side wall are connected to the plastic piece.Type: ApplicationFiled: September 10, 2018Publication date: January 3, 2019Inventors: Qiyuan Wang, Yunnan Lin, Liping Lin
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Patent number: 10100983Abstract: A light bulb apparatus has a plurality of LED modules, a substrate, a driver circuit board, a plastic piece, a radiator and a lamp cap. The substrate has aluminum material for mounting the plurality of LED modules, a first connection end and a second connection end. The first connection end and the second connection end is electrically connected to the plurality of LED modules. The plastic piece with a guiding groove is used for inserting the driver circuit board. The radiator has a top plate and a side wall. The substrate is fixed on the top plate, and the side wall are connected to the plastic piece.Type: GrantFiled: April 3, 2018Date of Patent: October 16, 2018Assignee: XIAMEN ECO LIGHTING CO. LTD.Inventors: Qiyuan Wang, Yunnan Lin, Liping Lin
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Publication number: 20180224071Abstract: A light bulb apparatus has a plurality of LED modules, a substrate, a driver circuit board, a plastic piece, a radiator and a lamp cap. The substrate has aluminum material for mounting the plurality of LED modules, a first connection end and a second connection end. The first connection end and the second connection end is electrically connected to the plurality of LED modules. The plastic piece with a guiding groove is used for inserting the driver circuit board. The radiator has a top plate and a side wall. The substrate is fixed on the top plate, and the side wall are connected to the plastic piece.Type: ApplicationFiled: April 3, 2018Publication date: August 9, 2018Inventors: Qiyuan Wang, Yunnan Lin, Liping Lin
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Patent number: 9970599Abstract: A light bulb apparatus has a plurality of LED modules, a substrate, a driver circuit board, a plastic piece, a radiator and a lamp cap. The substrate has aluminum material for mounting the plurality of LED modules, a first connection end and a second connection end. The first connection end and the second connection end is electrically connected to the plurality of LED modules. The plastic piece with a guiding groove is used for inserting the driver circuit board. The radiator has a top plate and a side wall. The substrate is fixed on the top plate, and the side wall are connected to the plastic piece.Type: GrantFiled: November 7, 2017Date of Patent: May 15, 2018Assignee: XIAMEN ECO LIGHTING CO. LTD.Inventors: Qiyuan Wang, Yunnan Lin, Liping Lin
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Publication number: 20180066806Abstract: A light bulb apparatus has a plurality of LED modules, a substrate, a driver circuit board, a plastic piece, a radiator and a lamp cap. The substrate has aluminum material for mounting the plurality of LED modules, a first connection end and a second connection end. The first connection end and the second connection end is electrically connected to the plurality of LED modules. The plastic piece with a guiding groove is used for inserting the driver circuit board. The radiator has a top plate and a side wall. The substrate is fixed on the top plate, and the side wall are connected to the plastic piece.Type: ApplicationFiled: November 7, 2017Publication date: March 8, 2018Inventors: Qiyuan Wang, Yunnan Lin, Liping Lin
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Patent number: 9841148Abstract: An electrical connection structure (100) of a lamp cap, comprising a substrate (20), a plastic piece (30) and a lamp cap (60), wherein the lamp cap (60) comprises a first electrode (61) and a second electrode (62). The first electrode (61) is insulated from the second electrode (62) and the second electrode (62) is fixed to the first electrode (61). The first electrode (61) is electrically connected to the first connection end (21). The second electrode (62) is of a rod-shaped structure. The second connection end (22) comprises a connection part (222) and a contact part (221). The connection part (222) is electrically connected to the electronic element on the substrate (20), and the contact part (221) is electrically connected to one end of the second electrode (62). The electrical connection structure (100) of a lamp cap has the advantages of simple structure and convenient automation of assembly.Type: GrantFiled: June 26, 2017Date of Patent: December 12, 2017Assignee: XIAMEN ECO LIGHTING CO. LTD.Inventors: Qiyuan Wang, Yunnan Lin, Liping Lin
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Patent number: 9719638Abstract: An electrical connection structure (100) of a lamp cap, comprising a substrate (20), a plastic piece (30) and a lamp cap (60), wherein the lamp cap (60) comprises a first electrode (61) and a second electrode (62). The first electrode (61) is insulated from the second electrode (62) and the second electrode (62) is fixed relative to the first electrode (61). The plastic piece (30) is arranged above the first electrode (61). An electronic element, and a first connection end (21) and a second connection end (22) which are electrically connected to the electronic element, are provided on the substrate (20). The first electrode (61) is electrically connected to the first connection end (21). The second electrode (62) is of a rod-shaped structure. The second connection end (22) comprises a connection part (222) and a contact part (221).Type: GrantFiled: February 14, 2017Date of Patent: August 1, 2017Assignee: XIAMEN ECO LIGHTING CO. LTD.Inventors: Qiyuan Wang, Yunnan Lin, Liping Lin
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Patent number: 9605811Abstract: An electrical connection structure (100) of a lamp cap, comprising a substrate (20), a plastic piece (30) and a lamp cap (60), wherein the lamp cap (60) comprises a first electrode (61) and a second electrode (62). The first electrode (61) is insulated from the second electrode (62) and the second electrode (62) is fixed relative to the first electrode (61). The plastic piece (30) is arranged above the first electrode (61). An electronic element, and a first connection end (21) and a second connection end (22) which are electrically connected to the electronic element, are provided on the substrate (20). The first electrode (61) is electrically connected to the first connection end (21). The second electrode (62) is of a rod-shaped structure.Type: GrantFiled: January 24, 2015Date of Patent: March 28, 2017Assignee: XIAMEN ECO LIGHTING CO. LTD.Inventors: Qiyuan Wang, Yunnan Lin, Liping Lin
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Publication number: 20160341369Abstract: An electrical connection structure (100) of a lamp cap, comprising a substrate (20), a plastic piece (30) and a lamp cap (60), wherein the lamp cap (60) comprises a first electrode (61) and a second electrode (62). The first electrode (61) is insulated from the second electrode (62) and the second electrode (62) is fixed relative t o the first electrode (61). The plastic piece (30) is arranged above the first electrode (61). An electronic element, and a first connection end (21) and a second connection end (22) which are electrically connected to the electronic element, are provided on the substrate (20). The first electrode (61) is electrically connected to the first connection end (21). The second electrode (62) is of a rod-shaped structure.Type: ApplicationFiled: January 24, 2015Publication date: November 24, 2016Inventors: QIYUAN WANG, YUNNAN LIN, LIPING LIN
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Patent number: 8685997Abstract: New camptothecin derivatives with the following structure of the formula (I), their use and the pharmaceutical compositions containing the same. The compounds of the present invention have good anti-tumor activities and good solubility in water, and can be used in development of medicines.Type: GrantFiled: January 17, 2007Date of Patent: April 1, 2014Assignee: Shanghai Institute of Materia Medica, Chinese Academy of SciencesInventors: Wei Lu, Jian Ding, Heyong Gao, Liping Lin, Yi Chen
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Publication number: 20090325996Abstract: New camptothecin derivatives with the following structure of the formula (I), their use and the pharmaceutical compositions containing the same. The compounds of the present invention have good anti-tumor activities and good solubility in water, and can be used in development of medicines.Type: ApplicationFiled: January 17, 2007Publication date: December 31, 2009Inventors: Wei Lu, Jian Ding, Heyong Gao, Liping Lin, Yi Chen
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Patent number: 7541463Abstract: The invention discloses novel sulfur-containing naphthalimide derivatives, and the preparation and uses thereof. The conjugated plane of naphthalimide derivatives of the invention is enlarged by incorporating 5-or 6-membered heteroaromatic ring and/or introducing S heteroatom, thus increasing the anti-tumor activity of naphthalimide. The compounds of the invention displays significant inhibiting activities to the proliferation of various tumor cells such as human lung cancer, gastric cancer, liver cancer, leucocythemia and the like. The inhibition of cell proliferation is dose-dependent.Type: GrantFiled: October 31, 2005Date of Patent: June 2, 2009Assignees: East China University of Science and Technology, Shanghai Institute of Materia Medica, Chinese Academy of Science, Dalian University of TechnologyInventors: Xuhong Qian, Yonggang Li, Yufang Xu, Jian Ding, Liping Lin, Zehong Miao, Hong Zhu, Baoyuan Qu
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Publication number: 20080234287Abstract: The invention discloses novel sulfur-containing naphthalimide derivatives, and the preparation and uses thereof. The conjugated plane of naphthalimide derivatives of the invention is enlarged by incorporating 5- or 6-membered heteroaromatic ring and/or introducing S heteroatom, thus increasing the anti-tumor activity of naphthalimide. The compounds of the invention displays significant inhibiting activities to the proliferation of various tumor cells such as human lung cancer, gastric cancer, liver cancer, leucocythemia and the like. The inhibition of cell proliferation is dose-dependent.Type: ApplicationFiled: May 7, 2008Publication date: September 25, 2008Inventors: Xuhong Qian, Yonggang Li, Yufang Xu, Jian Ding, Liping Lin, Zehong Miao, Hong Zhu, Baoyuan Qu