Patents by Inventor Lisa Marie Byrne

Lisa Marie Byrne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6652857
    Abstract: The present invention includes methods for generating neutralizing antitoxin directed against verotoxins. In preferred embodiments, the antitoxin directed against these toxins is produced in avian species using soluble recombinant verotoxin proteins. This antitoxin is designed so as to be administrable in therapeutic amounts and may be in any form (i.e., as a solid or in aqueous solution). These antitoxins are useful in the treatment of humans and other animals intoxicated with at least one bacterial toxin, as well as for preventive treatment, and diagnostic assays to detect the presence of toxin in a sample.
    Type: Grant
    Filed: June 16, 1999
    Date of Patent: November 25, 2003
    Assignee: Promega Corporation
    Inventors: James A. Williams, Lisa Marie Byrne, Charles S. G. Pugh
  • Publication number: 20020012658
    Abstract: The present invention includes methods for generating neutralizing antitoxin directed against verotoxins. In preferred embodiments, the antitoxin directed against these toxins is produced in avian species using soluble recombinant verotoxin proteins. This antitoxin is designed so as to be administrable in therapeutic amounts and may be in any form (i.e., as a solid or in aqueous solution). These antitoxins are useful in the treatment of humans and other animals intoxicated with at least one bacterial toxin, as well as for preventive treatment, and diagnostic assays to detect the presence of toxin in a sample.
    Type: Application
    Filed: June 16, 1999
    Publication date: January 31, 2002
    Inventors: JAMES A. WILLIAMS, LISA MARIE BYRNE, CHARLES S.G. PUGH
  • Patent number: 6080400
    Abstract: The present invention includes methods for generating neutralizing antitoxin directed against verotoxins. In preferred embodiments, the antitoxin directed against these toxins is produced in avian species using soluble recombinant verotoxin proteins. This antitoxin is designed so as to be administrable in therapeutic amounts and may be in any form (i.e., as a solid or in aqueous solution). These antitoxins are useful in the treatment of humans and other animals intoxicated with at least one bacterial toxin, as well as for preventive treatment, and diagnostic assays to detect the presence of toxin in a sample.
    Type: Grant
    Filed: March 13, 1997
    Date of Patent: June 27, 2000
    Assignee: Ophidian Pharmaceuticals, Inc.
    Inventors: James A. Williams, Lisa Marie Byrne