Abstract: The stress reducing sleep mask uses a construction of layered lightweight fabrics that, when combined through the manufacturing process, effectively block light, enhance air flow, and improve comfort. The unique combination of materials and molded construction (forming) allows the mask to conform as needed around specific facial anatomical landmarks, reducing gaps that allow light filtration. This device includes a refined headband adjustment, which eliminates the need for uncomfortable buckles, or applications that create other forms of discomfort due to sleeping position or hair entanglements. An integrated acupressure device, which has been shown in clinical studies to induce calm and relaxation, helps users to fall asleep more easily. The pressure of the device can be controlled through adjustment of the headband.

Abstract: The present disclosure provides novel pladienolide compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancers, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful. Also provided herein are methods of treating cancers by administering at least one compound disclosed herein and at least one additional therapy.

Abstract: The stress reducing sleep mask uses a construction of layered lightweight fabrics that, when combined through the manufacturing process, effectively block light, enhance air flow, and improve comfort. The unique combination of materials and molded construction (forming) allows the mask to conform as needed around specific facial anatomical landmarks, reducing gaps that allow light filtration. This device includes a refined headband adjustment, which eliminates the need for uncomfortable buckles, or applications that create other forms of discomfort due to sleeping position or hair entanglements. An integrated acupressure device, which has been shown in clinical studies to induce calm and relaxation, helps users to fall asleep more easily. The pressure of the device can be controlled through adjustment of the headband.

Abstract: Disclosed are highly extensible bonded webs or multilayered sheets containing these. These products can be processed in a ring-roll process without damage. The bonded webs or multilayered sheets can be used, for example in the manufacture of diapers.

Abstract: A satellite radio system may include at least one computing device configured to receive a transaction date associated with a vehicle, to determine a preactivation duration based on the date, and to determine whether the preactivation duration exceeds a predetermined time period. The at least one computing device may be further configured to initiate the transmission of deactivation information for a satellite radio module in the vehicle if the preactivation duration exceeds the predetermined time period to disable the module from playing satellite broadcast signals.

Abstract: A satellite radio system may include at least one computing device configured to receive a transaction date associated with a vehicle, to determine a preactivation duration based on the date, and to determine whether the preactivation duration exceeds a predetermined time period. The at least one computing device may be further configured to initiate the transmission of deactivation information for a satellite radio module in the vehicle if the preactivation duration exceeds the predetermined time period to disable the module from playing satellite broadcast signals.

Abstract: An aspect of the invention provides a method for providing satellite radio service in a vehicle. A satellite radio may be activated before a customer purchases the vehicle. The satellite radio may remain active until it receives a deactivation signal.

Abstract: An aspect of the invention provides a method for providing satellite radio service in a vehicle. A satellite radio may be activated before a customer purchases the vehicle. The satellite radio may remain active until it receives a deactivation signal.