Patents by Inventor Livio Brasili

Livio Brasili has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 1,3-oxathiolanes and substituted 1,3-dithiolanes with antiviral properties
    Patent number: 5587480
    Abstract: This invention relates to novel substituted 1,3-oxathiolanes and substituted 1,3-dithiolanes or pharmaceutically acceptable salts and esters thereof, of the formula: ##STR1## wherein X is S, S.dbd.O, or SO.sub.2 ;Y is O, S, S.dbd.O, or SO.sub.2 ;R.sub.1 is hydrogen, trisubstituted silyl, C.sub.1-6 alkyl, aralkyl, or C.sub.1-6 acyl, and R.sub.2 is a pyrimidine base or an analogue or derivative thereof.This invention also relates to processes for preparing these compounds, intermediates useful in their preparation, to pharmaceutical compositions containing them and to the use of these compounds as antiviral agents.
    Type: Grant
    Filed: April 20, 1994
    Date of Patent: December 24, 1996
    Assignee: BioChem Pharma, Inc.
    Inventors: Bernard Belleau, deceased, Nghe Nguyen-Ba, Laval C. C. Kong, Tarek Mansour, Haolun Jin, Livio Brasili