Abstract: The disclosure discloses a method for manufacturing special purpose vehicle wheels by using 7000 series aluminum alloys, comprising the following steps: step 1, smelting 7000 series aluminum alloys in a smelting furnace; step 2, making the solution obtained in step 1 into an aluminum alloy ingot blank through a spraying and forming process; step 3, extruding the aluminum alloy ingot blank of step 2 to obtain an extrusion bar; step 4, sawing the extrusion bar into blanks and heating them; step 5, rolling the blank into a cake; step 6, putting the cake into a press for forging and forming; step 7, spinning and forming the wheel rim. The wheel manufactured by the method for manufacturing special vehicle wheels with 7000 series aluminum alloys in the present disclosure has high and stable conductivity, qualified impact test and good bending and radial fatigue performance.

Abstract: Disclosed are an anti-overturning warning method and an anti-overturning warning apparatus for a work machine, a work machine and an electronic device. The anti-overturning warning method includes: acquiring a plurality of positive pressures collected by a plurality of pressure sensors. The plurality of pressure sensors are respectively provided at a plurality of supporting wheels of the work machine; obtaining an intersection point where a gravity direction of the work machine intersects a ground based on the plurality of positive pressures; and obtaining an outer contour of the plurality of supporting wheels, and performing a warning of an overturning risk of the work machine based on the intersection point and the outer contour of the plurality of supporting wheels.

Abstract: A charge/discharge test apparatus includes a temperature control box having a test chamber provided inside and provided with an opening communicated with the test chamber and configured for extraction or insertion of a battery, and a rack connected to the temperature control box. The rack and the opening are located at different sides of the temperature control box, and the rack has an accommodating cavity inside. The charge/discharge test apparatus further includes a charge/discharge module located in the accommodating cavity and configured to charge/discharge a battery in the corresponding test chamber.

Abstract: The present application discloses a dispatching and control cloud data processing method, device and system. The method includes the following operations: pilot node device acquires a global scheduling task, decomposes the global scheduling task to obtain scheduling tasks, issues the scheduling tasks to collaborative node device, acquires data collection ranges and data processing rules of the collaborative node devices, and delivers them to the collaborative node devices; the collaborative node devices receive and execute the scheduling tasks issued by the pilot node device; receives the data collection ranges and the data processing rules issued by the pilot node device, acquires, based on the scheduling tasks, collected data in the data collection ranges, processes the acquired collected data according to the data processing rules to obtain the processed data, uploads the processed data to the pilot node device; the pilot node device receives the processed data uploaded by the collaborative node devices.

Abstract: Provided is a fusion protein dimer using an antibody Fc region as the backbone, comprising a first and a second polypeptide chain. The first polypeptide chain comprises a first antibody Fc region and one or more single-domain antibodies fused to the first antibody Fc region. The second polypeptide chain comprises a second antibody Fc region and one or more single domain antibodies fused to the second antibody Fc region. The first polypeptide chain and/or the second polypeptide chain further comprise a cytokine fused to the Fc region of the respective antibody. Further provided is use of the fusion protein dimer in preparing an immunotherapeutic drug for treating tumors. The Fc fusion protein heterodimer not only increases the activity of a single domain antibody, but also significantly improves the biological activity of a cytokine.

Abstract: Disclosed is a method and an apparatus NER-orientated Chinese clinical text data augmentation, and unannotated data and annotated data of label linearization processing through data preprocessing. A concealed part is predicted based on retained information by using the unannotated data and concealing part of information in text, and meanwhile an entity word-level discrimination task is introduced for pre-training of a span-based language model; and a plurality of decoding mechanisms are introduced in a fine-tune stage, a relationship between a text vector and text data is obtained based on the pre-trained span-based language model, linearized data with entity labels is converted into the text vector, and text generation is performed through forward decoding and reverse decoding in a prediction stage of a text generation model to obtain enhanced data with annotation information.

Abstract: A titanium dioxide micro-nanocontainers, corrosion-resistant waterborne epoxy coatings and preparation method thereof, including preparation steps as follows: TiO2 micro-nano spheres are synthesized by applying hydrothermal method; a polyaniline layer doped with molybdate ions is deposited on the surface of TiO2 micro-nano spheres by adopting the method of in-situ chemical polymerization, TiO2/PANI-MoO42? micro-nano-spheres are obtained, then, polydopamine is encapsulated on the surface of TiO2/PANI-MoO42? micro-nano spheres to obtain titanium dioxide micro-nanocontainers; next, antirust filler, defoamer, dispersant and thickener are added into waterborne epoxy emulsion, then titanium dioxide micro-nanocontainers are added in the waterborne epoxy emulsion for dispersing and grinding, filtering and encapsulating to obtain component A; the waterborne epoxy curing agent and deionized water are mixed in proportion to obtain component B; component A is stirred, then it is mixed with the component B in proportion,

Abstract: The present disclosure provides a kit and method for constructing a long-acting depression animal model. The present disclosure adopts Bacille Calmette-Guerin (BCG) (or Mycobacterium bovis (M bovis)) and low-dose pertussis toxin (PTX) for combined induction, which greatly reduces modeling cost. A mouse model constructed by the method of the present disclosure can clearly distinguish a time interval of pathological behaviors from a time interval of depression-like behaviors and has prominent face validity and predictive validity. The method of the present disclosure is simple and convenient and does not require a large number of tedious daily operations as the depression model construction by chronic unpredictable stress, chronic restraint stress, social defeat, mother-child separation, or the like. The mouse model of the present disclosure can provide a valuable long-term intervention window for research on antidepressant therapy.

Abstract: The present disclosure provides a sputtering reaction chamber and a process assembly of the sputtering reaction chamber. The process assembly includes a liner, and the liner includes an integrally formed body member and a cover member. The cover member may extend from a bottom of the body member to an inner side of the body member and may be configured to press an edge of a to-be-processed workpiece when a process is performed. A cooling channel may be arranged in the cover member and the body member and may be configured to cool the cover member and the body member by transferring coolant. The process assembly of the sputtering reaction chamber and the sputtering reaction chamber provided by the present disclosure can reduce heat radiation of the process assembly to the to-be-processed workpiece and released gases and impurities to effectively reduce a whisker defect and improve a product yield.

Abstract: Provided by the present application are a method and a device for constructing integrated space-terrestrial network, the method including: obtaining a target constellation and standardizing a relative motion between each target satellite in the target constellation and earth's surface according to a principle of making a satellite running in a recursive earth-repeat orbit have fixed satellite subpoint trajectories; obtaining a recursively extended topological structure according to the target constellation; according to the extended topological structure, dividing geographical cells and obtaining a mapping relationship between the geographical cells and the satellite subpoint trajectories to facilitate network addressing and networking management based on geographical location; and performing, based on a deployment rule, a recursive incremental deployment according to the extended satellite network topological structure, and realizing integrated space-terrestrial network.

Abstract: A medical image processing apparatus according to one embodiment includes processing circuitry. The processing circuitry trains an attention model by using a medical image and a mask image that is obtained by performing mask processing on a region other than a region of interest in the medical image, trains an image processing model by using the medical image, a heatmap corresponding to the medical image, and an attention feature that indicates attention of the region of interest in the trained attention model, combines, as an attention image processing model, an attention extraction module that includes an attention module for outputting the attention feature and the trained image processing model, performs processing on the medical image by using the attention image processing model, and generates a heatmap for determining a position of a landmark in the medical image.

Abstract: This disclosure provides a sealing cover, belonging to the technical field of sealing containers. The sealing cover comprises: a cover body provided with a through hole; a knob, rotatably arranged on one side of the cover body and provided with protrusion parts; a bottom plate, movably arranged on the other side of the cover body and able to move close to or away from the cover body, the bottom plate being provided with a linkage part, the linkage part passing through the through hole, spiral grooves being formed in a peripheral surface of the linkage part, the protrusion parts being connected to the spiral grooves and able to move along the spiral grooves; and a seal ring arranged between the bottom plate and the cover body. Further provided is a sealing container, comprising a sealing cover and a container body, wherein a cover body of the sealing cover is fitted to cover the container body.

Abstract: The present invention relates to compounds for targeted immunotherapy, as well as compositions comprising the same. Further, the present invention relates to the use of the compounds in the treatment of diseases such as cancer.

Abstract: Described herein are 2-amino-quinoline derivatives that are agonists of toll-like receptors 7 and 8 (TLR7/8), pharmaceutical compositions, and methods of use of the compounds and compositions to treat various diseases, such as viral, cancer, and allergic diseases, in need thereof by administering a therapeutically effective amount of a 2-amino-quinoline derivative.

Abstract: The present invention provides a push type cup lid, which has a lid body, provided with a water outlet; a flip-top lid for covering the water outlet, the flip-top lid being rotatably connected with the lid body; a sealing assembly for plugging the water outlet, the sealing assembly being movably connected with the lid body; and a button arranged on the lid body in a pressed manner, both the sealing assembly and the flip-top lid being in linked connection with the button. The present invention has the beneficial effects that according to the cup lid, the water outlet is plugged by the sealing assembly and the water outlet is further covered by the flip-top lid, so that the reliability of the cup lid which is closed is ensured; when it is opened, the sealing assembly and the flip-top lid can be opened simultaneously by pressing the button.

Abstract: A method for checking a medium-term and long-term maintenance plan of a power grid. A predicted load value and one or more historical load values of a power grid are acquired and clustered through a clustering algorithm, and a historical moment at which a historical load value is in a same cluster as the predicted load value and has a largest load value is selected as a target historical moment. A power grid operation mode model at the target historical moment is acquired, and the power grid operation mode model is updated according to the maintenance plan and open loop point information by using a full wiring approach to obtain a future-state power grid operation mode model. Ground state power flow data of the power grid are calculated based on the operation mode model, and safety check is carried out according to a preset ground state power flow limit.

Abstract: A method and apparatus for checking power grid measurement data, a device, a storage medium and a program product. The method includes: a feature factor of power grid measurement data is extracted; power balance of a set time scale is checked based on the measurement data and the feature factor to obtain a check result; a classification rule base of abnormal problems of measurement data is built based on the check result; and an abnormal problem in target measurement data is checked based on the classification rule base of abnormal problems of measurement data, to obtain a measurement data quality report.

Abstract: The present specification provides methods of monotherapy for cancer using an imidazoquinolinamine drug. Further methods provide for coordination with immune checkpoint inhibitor therapy for cancer.

Abstract: The present invention relates to compounds for targeted immunotherapy, as well as compositions comprising the same. Further, the present invention relates to the use of the compounds in the treatment of HER2 positive tumors/cancers.

Abstract: The present invention relates to therapeutic combinations and methods for treating cancers using combination therapy.