Abstract: The present disclosure belongs to the technical field of wastewater treatment, and discloses an electrochemical nitrogen and phosphorus removal device and a method.

Abstract: The present disclosure provides a kit and method for constructing a long-acting depression animal model. The present disclosure adopts Bacille Calmette-Guerin (BCG) (or Mycobacterium bovis (M bovis)) and low-dose pertussis toxin (PTX) for combined induction, which greatly reduces modeling cost. A mouse model constructed by the method of the present disclosure can clearly distinguish a time interval of pathological behaviors from a time interval of depression-like behaviors and has prominent face validity and predictive validity. The method of the present disclosure is simple and convenient and does not require a large number of tedious daily operations as the depression model construction by chronic unpredictable stress, chronic restraint stress, social defeat, mother-child separation, or the like. The mouse model of the present disclosure can provide a valuable long-term intervention window for research on antidepressant therapy.

Abstract: The present disclosure provides compounds of Formula I, or pharmaceutically acceptable salts thereof, that modulate the activity of phosphoinositide 3-kinases-gamma (PI3K?) and are useful in the treatment of diseases related to the activity of PI3K? including, for example, autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.

Abstract: An application of a prokaryotic Argonaute protein with only a cleavage activity of a target ribonucleic acid (RNA) in RNA editing is provided. The Argonaute protein is derived from a mesophilic prokaryotes Verrucomimicrobia bacterium, and its amino acid sequence is shown in SEQ ID NO: 1 or a protein with high similarity to SEQ ID NO: 1 and the same function. This protein has binding activity to a single-stranded guide DNA and nuclease activity only to the target RNA complementarily paired with the single-stranded guide DNA. Therefore, the protein can be utilized for in vitro and in vivo targeted RNA editing, providing a new powerful tool for RNA editing.

Abstract: A fluid control assembly and a fluid control device are provided. The fluid control assembly includes a valve body component and a valve core component. At least part of the valve core component is located in a valve cavity. The valve body component is provided with a body portion and a protruding portion. The body portion forms at least part of a wall portion of the valve cavity, and the protruding portion protrudes from the peripheral wall of the body portion. The fluid control assembly is provided with a first flow channel, and at least part of the first flow channel is located in the valve core component. The protruding portion is provided with two or more lugs, at least some of the lugs are provided with the second flow channels, and circulation ports of at least some of the second flow channels have the same orientation.

Abstract: A drive device includes a housing, a motor and a transmission assembly; the housing includes a first casing and a second casing; the first casing includes a first protruding portion and a second protruding portion; the second casing includes a third protruding portion; the transmission assembly includes a first-stage worm, a second-stage worm and a transmission wheel; the first-stage worm includes a first tooth-shaped portion; the second-stage worm includes a second tooth-shaped portion; the first protruding portion and the second protruding portion both limitedly cooperate with the second-stage worm; along the axial direction of the second tooth-shaped portion, the first protruding portion is located on one side of the second tooth-shaped portion; the second protruding portion is located on the other side of the second tooth-shaped portion; and the distance between the third protruding portion and the transmission wheel is within a preset range.

Abstract: A fully automated towing, alignment and hangar system suitable for an offshore operation helicopter includes a quick mooring device, a wide-angle camera installed on a rear wall of the quick mooring device, a longitudinal towing device, a DSP control unit, an MCU control unit, a helicopter and a mooring bar thereof. An alignment method based on above system includes following steps of acquiring an attitude image of a steering wheel, calculating a helicopter yaw angle and a steering wheel deflection angle, calculating position coordinates of the steering wheel, a first wheel and a second wheel in a deck coordinate system, judging boundaries relative to a towing indication line, extracting an optimal path suitable for the movement of the helicopter, calculating lateral and longitudinal movement position control commands, driving the movement of the helicopter, and repeating the above operations until the automated towing, alignment and hangar are completed.

Abstract: A fluid control valve is disclosed, comprising a driving assembly, a valve core assembly, and a main valve body. The valve core assembly can be driven by the driving assembly to rotate; the main valve body is provided with a valve body part and at least two adapter parts; each adapter part extends radially outwards from a side wall of the valve body part, the adapter part is provided with an adapter channel, and the adapter part further has an adapter port corresponding to and communicated with the adapter channel; an opening of the adapter port of each adapter part faces a side of the adapter part facing away from the driving assembly.

Abstract: A reconfigurable polarization rotator is formed of an array of very small liquid crystal (LC) cells (e.g., cells of less than 10 ?m in width, termed “microcells”), referred to hereinafter as “microcells”. Each LC microcell is addressable by a separate electrical voltage input that independently controls the polarization rotation performed by the associated LC microcell. By defining a set of adjacent microcells to be held at the same voltage level, that group may be used to form a polarization rotator window of a proper size for a first fiber array configuration. When a fiber array of a different configuration (say, an array with twice the pitch) is used, a different-sized group of adjacent LC microcells is held at a common voltage level so as to form a reconfigured “window” of a new dimension.

Abstract: A control valve is provided, which comprises a valve body and a valve element. The valve element can be driven to rotate, the valve element is provided with an external communicating cavity and a first cavity, and the valve element comprises a first partition plate, a first valve element shaft and a first reinforcing rib; the first reinforcing rib comprises a first end portion, a second end portion and a first main body portion in a height direction of the valve element and the first main body portion is connected between the first end portion and the second end portion, and there is a height difference between the first end portion and the second end portion.

Abstract: A seal, a fluid assembly comprising same, and a fluid device. The seal comprises a body portion; first through holes are formed in the seal; the seal further has first sealing portions corresponding to the first through holes; there are at least two first through holes; each first sealing portion comprises a first extension portion and a second extension portion; the first extension portion and the second extension portion are located on opposite sides of the body portion; the first extension portion and the second extension portion extend from the body portion toward the first through holes; the distance between the first extension portion and the second extension portion is greater than the height of the body portion; and the first extension portion is a closed raised structure, and the second extension portion is also a closed raised structure.

Abstract: A method for manufacturing a control valve, and a control valve and a valve body assembly. The method for manufacturing a control valve comprises: injection-molding a housing, fixedly connecting a sealing assembly to the housing, and mounting a valve core assembly. The housing comprises an annular side wall, and the housing has a first communication port. The sealing assembly is fixed to an inner surface of the annular side wall, the sealing assembly comprises a second communication port that corresponds to the first communication port and is in mutual communication with same, and the sealing assembly is fixedly connected to the inner surface of the annular side wall and forms a first sealing face on the periphery of the first communication port. The valve core assembly is inserted into a space formed by the sealing assembly, and is tightly fitted with an inner surface of the sealing assembly.

Abstract: Provided are a driving device and a valve, the driving device includes a motor and a transmission assembly; an output shaft of the motor is connected to the transmission assembly, and the transmission assembly includes a transmission member; the transmission member and the output shaft are fixed to or are limitedly cooperate with one another, and the output shaft may drive the transmission member to rotate; the transmission assembly further includes a magnetic element; and the driving device further includes a Hall element corresponding to the magnetic element; the transmission member includes a cylindrical portion, and the cylindrical portion is provided with a first hole passage; the first hole passage includes a first opening portion located on an outer wall portion of the cylindrical portion, and at least a part of the magnetic element passes through the first opening portion to extend into the first hole passage.

Abstract: A control valve and a thermal management assembly including the control valve are provided. The control valve includes a valve body component and a valve core; the valve body component is provided with interface channels, the valve core is provided with flow guiding channels, there are N flow guiding channels, and there are 2N interface channels, wherein N?3 and N is an integer; by rotating the valve core, the 2N interface channels can implement communication between each two interface channels in different forms by the N flow guiding channels; in this way, when the control valve is applied to the thermal management assembly, the control valve can control multiple flow paths in the thermal management assembly by rotating the valve core.

Abstract: An image processing method is provided, the method includes: performing area division on an input image to obtain a plurality of sub-images; determining a part of the plurality of sub-images as an image to be output; stitching respective sub-images of the image to be output to obtain a stitched image; and transmitting the stitched image, wherein the stitched image is smaller than the input image. An image jointing method is provided, the method includes: receiving a stitched image obtained by the image processing method according to the present disclosure; extracting respective sub-images of an image to be output from the stitched image; and jointing the respective sub-images to obtain a display image, wherein the jointing the respective sub-images refers to obtaining the display image by an operation inverse to a stitching process of stitching the respective sub-images to obtain the stitched image.

Abstract: A control valve and a control valve system. The control valve comprises a valve body and valve cores; the valve cores comprise a first valve core and a second valve core; the control valve comprises a valve cavity; the valve body has multiple ports; the first valve core and the second valve core are located in the valve cavity; rotation of the valve cores can open or close ports corresponding to fluid channels of the valve cores. The control valve further comprises a first transmission portion and a second transmission portion, the first transmission portion and the first valve core are integrally formed or in transmission connection, and the second transmission portion and the second valve core are integrally formed or in transmission connection; a valve core shaft and the first valve core are in transmission connection.

Abstract: The present invention relates to a preparation method for and an application of a chiral spirocyclic phosphine-nitrogen-phosphine tridentate ligand SpiroPNP and an iridium catalyst Ir-SpiroPNP thereof. The chiral spirocyclic phosphine-nitrogen-phosphine tridentate ligand is a compound represented by formula I, or a racemate or optical isomer thereof, or a catalytically acceptable salt thereof, and the main structural feature is a phosphine ligand having a chiral spiro indene skeleton and a large sterically hindered substituent. The chiral spirocyclic phosphine-nitrogen-phosphine tridentate ligand can be synthesized into a chiral starting material from a 7-diaryl/alkylphosphino-7?-amino-1,1?-spirodihydroindenyl compound having a spiro ring skeleton. The iridium catalyst of the chiral spirocyclic phosphino-7?-amino-1,1?-spirodihydroindenyl compound having a sprio ring skeleton.

Abstract: A module handles beams having multiple channels in an optical network. The module has a dispersion element, a liquid crystal (LC) based switching assembly, and photodetectors. The dispersion element is arranged in optical communication with the beams from inputs and is configured to disperse the beams into the channels across a dispersion direction. The switching assembly is arranged in optical communication with the channels from the dispersion element and is configured to selectively reflect the channels using electrically switchable cells of one or more LC-based switching engines. The photodetectors are arranged in optical communication with the dispersion element, and each are configured to receive selectively reflected channels for optical channel monitoring. Outputs can be arranged in optical communication with the dispersion element and can be configured to receive selectively reflected channels for wavelength selective switching.

Abstract: The present invention provides methods for improving or accelerating wound healing in a subject comprising administering to a wound of the subject in need thereof an agent that suppresses expression of a clock gene, wherein the clock gene is neuronal PAS domain protein 2 (Npas2). This invention also relates to methods for regenerating alveolar bone, regenerating connective tissue at a wound site, and for decreasing wound area size comprising administering to a bone loss site or a wound site, in particular, an open wound site, of a subject an agent that suppresses expression of Npas2.

Abstract: An electric valve, comprising a housing and an end cover. A cavity and a valve port are formed in the housing. The electric valve further comprises a rotor assembly, a rod assembly, and a valve core assembly; the rotor assembly is connected to one end of the rod assembly; and the other end of the rod assembly is connected to the valve core assembly. The electric valve further comprises a sealing component, and the sealing component is distant from the valve port with respect to the valve core assembly; the sealing component comprises a first cylindrical portion, a membrane portion, and an annular sealing portion; by providing the sealing component, the first cylindrical portion is connected to the rod assembly and a connection position is sealed.