Patents by Inventor Lois A. Tverberg

Lois A. Tverberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Calcitonin/calcitonin gene related peptide enhancer element and associated DNA binding proteins
    Patent number: 6159735
    Abstract: A DNA element which was isolated from the upstream regulatory region of the CT/CGRP gene and which exhibits cell-specific enhancement of transcription is described. The enhancer activity of the element is further regulated by members of the superfamily of steroids and retinoids which increase or decrease transcription in a cell-specific manner. Methods of gene regulation and therapeutic uses involving the DNA element are also described. Furthermore, proteins which bind to the element and regulate transcription of genes under the control of the DNA element are also described. These proteins can be used for purposes of regulation of gene expression.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: December 12, 2000
    Assignee: University of Iowa Research Foundation
    Inventors: Andrew F. Russo, Thomas M. Lanigan, Lois A. Tverberg
  • Calcitonin and calcitonin-gene related peptide enhancer element and associated DNA binding proteins
    Patent number: 5976788
    Abstract: A DNA element which was isolated from the upstream regulatory region of the CT/CGRP gene and which exhibits cell-specific enhancement of transcription is described. The enhancer activity of the element is further regulated by members of the superfamily of steroids and retinoids which increase or decrease transcription in a cell-specific manner. Methods of gene regulation and therapeutic uses involving the DNA element are also described. Furthermore, proteins which bind to the element and regulate transcription of genes under the control of the DNA element are also described. These proteins can be used for purposes of regulation of gene expression.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: November 2, 1999
    Assignee: University of Iowa Research Foundation
    Inventors: Andrew F. Russo, Lois A. Tverberg
  • Calcitonin/calcitonin gene related peptide enhancer element and associated DNA binding proteins
    Patent number: 5569604
    Abstract: A DNA element which was isolated from the upstream regulatory region of the CT/CGRP gene and which exhibits cell-specific enhancement of transcription is described. The enhancer activity of the element is further regulated by members of the superfamily of steroids and retinoids which increase or decrease transcription in a cell-specific manner. Methods of gene regulation and therapeutic uses involving the DNA element are also described. Furthermore, proteins which bind to the element and regulate transcription of genes under the control of the DNA element are also described. These proteins can be used for purposes of regulation of gene expression.
    Type: Grant
    Filed: September 3, 1993
    Date of Patent: October 29, 1996
    Assignee: The University of Iowa Research Foundation
    Inventors: Andrew F. Russo, Thomas M. Lanigan, Lois A. Tverberg