Patents by Inventor Lone B. Miller

Lone B. Miller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipid acyltransferase proteins and methods of making them
    Patent number: 9175271
    Abstract: The present invention provides a method for preparing a variant lipid acyltransferase enzyme by expressing a nucleotide sequence encoding a lipid acyltransferase which may comprise at least one modification at a position(s) which corresponds in the encoded amino acid sequence to an amino acid(s) located in a) the canyon region of the enzyme (i.e. preferably amino acid residues 31, 27, 85, 86, 119, and 120); and/or b) insertion site 1 (i.e. amino acid residues 22-36) and/or c) insertion site 2 (i.e. amino acid residues 74-88), wherein the canyon region, insertion site 1 and/or insertion site 2 are defined as that region which when aligned based on primary or tertiary structure corresponds to the canyon region, insertion site 1 or insertion site 2 (or the corresponding amino acid residues taught above) of the enzyme shown herein as SEQ ID No. 16 or 6 in a host organism.
    Type: Grant
    Filed: April 11, 2012
    Date of Patent: November 3, 2015
    Assignee: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Janne Brunstedt, Jens Frisbæk Sorensen, Jørn Borch Søe, Charlotte Johansen Vedel, Birgitte Ø. Wittschieben, Jørn Dalgaard Mikkelsen, Charlotte Horsmans Poulsen, Lene B. Jensen, Lone B. Miller, Morten K. Larsen, Rikke H. Lorentzen, Charlotte R. Thoudahl, Marguerite A. Cervin, Richard R. Bott
  • LIPID ACYLTRANSFERASE PROTEINS AND METHODS OF MAKING THEM
    Publication number: 20130034627
    Abstract: The present invention provides a method for preparing a variant lipid acyltransferase enzyme by expressing a nucleotide sequence encoding a lipid acyltransferase which may comprise at least one modification at a position(s) which corresponds in the encoded amino acid sequence to an amino acid(s) located in a) the canyon region of the enzyme (i.e. preferably amino acid residues 31, 27, 85, 86, 119, and 120); and/or b) insertion site 1 (i.e. amino acid residues 22-36) and/or c) insertion site 2 (i.e. amino acid residues 74-88), wherein the canyon region, insertion site 1 and/or insertion site 2 are defined as that region which when aligned based on primary or tertiary structure corresponds to the canyon region, insertion site 1 or insertion site 2 (or the corresponding amino acid residues taught above) of the enzyme shown herein as SEQ ID No. 16 or 6 in a host organism.
    Type: Application
    Filed: April 11, 2012
    Publication date: February 7, 2013
    Inventors: Janne Brunstedt, Jens Frisbæk Sorensen, Jørn Borch Søe, Charlotte Johansen Vedel, Birgitte Ø. Wittschieben, Jørn Dalgaard Mikkelsen, Charlotte Horsmans Poulsen, Lene B. Jensen, Lone B. Miller, Morten K. Larsen, Rikke H. Lorentzen, Charlotte R. Thoudahl, Marguerite A. Cervin, Richard R. Bott