Patents by Inventor Longhai Dai

Longhai Dai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cutinase having improved enzymatic activity
    Patent number: 11939603
    Abstract: A modified cutinase is disclosed. The cutinase has the modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of asparagine at position 181 with alanine, or substitutions of asparagine at position 181 with alanine and phenylalanine at position 235 with leucine. The modified enzyme has improved PET-hydrolytic activity, and thus, the high-activity PET hydrolase is obtained, and the industrial application value of the PET hydrolase is enhanced.
    Type: Grant
    Filed: June 21, 2023
    Date of Patent: March 26, 2024
    Assignee: HUBEI UNIVERSITY
    Inventors: Chun-Chi Chen, Jian-Wen Huang, Jian Min, Xian Li, Beilei Shi, Panpan Shen, Yu Yang, Yumei Hu, Longhai Dai, Lilan Zhang, Yunyun Yang, Rey-Ting Guo
  • PET hydrolase having improved thermal stability
    Patent number: 11680252
    Abstract: A PET hydrolase having improved thermal stability is disclosed. The PET hydrolase has a modified amino acid sequence of SEQ ID NO: 2 or a modified amino acid sequence with at least 80% sequence identity of SEQ ID NO: 2, wherein the modification is a substitution of asparagine at position 248 or a corresponding position with proline.
    Type: Grant
    Filed: November 22, 2021
    Date of Patent: June 20, 2023
    Assignee: HUBEI UNIVERSITY
    Inventors: Chun-Chi Chen, Jian-Wen Huang, Xiuqin Li, Wei Zeng, Lilan Zhang, Yunyun Yang, Longhai Dai, Jian Min, Yu Yang, Rey-Ting Guo
  • PET HYDROLASE HAVING IMPROVED THERMAL STABILITY
    Publication number: 20220307000
    Abstract: A PET hydrolase having improved thermal stability is disclosed. The PET hydrolase has a modified amino acid sequence of SEQ ID NO: 2 or a modified amino acid sequence with at least 80% sequence identity of SEQ ID NO: 2, wherein the modification is a substitution of asparagine at position 248 or a corresponding position with proline.
    Type: Application
    Filed: November 22, 2021
    Publication date: September 29, 2022
    Inventors: Chun-Chi Chen, Jian-Wen Huang, Xiuqin Li, Wei Zeng, Lilan Zhang, Yunyun Yang, Longhai Dai, Jian Min, Yu Yang, Rey-Ting Guo
  • Cellulase having improved enzymatic activity
    Patent number: 10479985
    Abstract: A cellulase having improved enzymatic activity is disclosed. The cellulase has a modified amino acid sequence of SEQ ID NO: 2 or a modified amino acid sequence with at least 80% sequence identity of SEQ ID NO: 2, wherein the modification is a substitution of methionine at position 120 or a corresponding position with asparagine.
    Type: Grant
    Filed: May 8, 2019
    Date of Patent: November 19, 2019
    Assignee: HUBEI UNIVERSITY
    Inventors: Chun-Chi Chen, Jian-Wen Huang, Longhai Dai, Xuejing Yu, Chin-Yu Chen, Shan Wu, Zhichun Zhan, Lilan Zhang, Chao Zhai, Lixin Ma, Rey-Ting Guo