Patents by Inventor Lorin Roskos

Lorin Roskos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-B7-H1 ANTIBODIES FOR TREATING TUMORS
    Publication number: 20240150469
    Abstract: Provided herein are methods of treating B7-H1-expressing tumors comprising administering an effective amount of MEDI4736 or an antigen-binding fragment thereof.
    Type: Application
    Filed: October 20, 2023
    Publication date: May 9, 2024
    Inventors: Rajest Narwal, David Fairman, Paul Robbins, Meina Liang, Amy Schneider, Carlos Chavez, Carina Herl, Min Pak, Hong Lu, Marlon Rebelatto, Keith Steele, AnnMarie Boutrin, Li Shi, SHENGYAN HONG, Brandon Higgs, Lorin Roskos
  • METHODS FOR DETERMINING TREATMENT FOR CANCER PATIENTS
    Publication number: 20230420081
    Abstract: Methods for determining treatments for cancer patients are disclosed.
    Type: Application
    Filed: September 13, 2023
    Publication date: December 28, 2023
    Inventors: Li Yu, Harry Yang, Mohammed Dar, Lorin Roskos, Jean-Charles Soria, Charles Ferte, Wei Zhao, Aline Gendrin Brokmann, Jolyon Faria, Pralay Mukhopadhyay, Ikbel Achour
  • Anti-B7-H1 antibodies for treating tumors
    Patent number: 11827706
    Abstract: Provided herein are methods of treating B7-H1-expressing tumors comprising administering an effective amount of MEDI4736 or an antigen-binding fragment thereof.
    Type: Grant
    Filed: October 16, 2020
    Date of Patent: November 28, 2023
    Inventors: Rajesh Narwal, David Fairman, Paul Robbins, Meina Liang, Amy Schneider, Carlos Chavez, Carina Herl, Min Pak, Hong Lu, Marlon Rebelatto, Keith Steele, Anmarie Boutrin, Li Shi, Shengyan Hong, Brandon Higgs, Lorin Roskos
  • ANTI-IFNAR1 DOSING REGIME FOR SUBCUTANEOUS INJECTION
    Publication number: 20230365698
    Abstract: The disclosure relates to methods and compositions for the treatment of type I IFN mediated disease. Specifically, the disclosure relates to a subcutaneous dose of a type I IFN receptor inhibitor.
    Type: Application
    Filed: April 21, 2023
    Publication date: November 16, 2023
    Inventors: Catharina LINDHOLM, Yen Lin CHIA, Rajendra TUMMALA, Lorin ROSKOS, Sr., Joachim ALMQUIST, Thomas ROUSE
  • Methods for determining treatment for cancer patients
    Patent number: 11798653
    Abstract: Methods for determining treatments for cancer patients are disclosed.
    Type: Grant
    Filed: October 18, 2019
    Date of Patent: October 24, 2023
    Assignee: MEDIMMUNE, LLC
    Inventors: Li Yu, Harry Yang, Mohammed Dar, Lorin Roskos, Jean-Charles Soria, Charles Ferte, Wei Zhao, Aline Gendrin Brokmann, Jolyon Faria, Pralay Mukhopadhyay, Ikbel Achour
  • TREATMENT OF LUPUS NEPHRITIS
    Publication number: 20220348669
    Abstract: The disclosure relates to methods and compositions for the treatment of lupus nephritis. Specifically, the disclosure relates to methods comprising administering to a subject a type I IFN receptor inhibitor.
    Type: Application
    Filed: April 22, 2022
    Publication date: November 3, 2022
    Applicant: AstraZeneca AB
    Inventors: Catharina LINDHOLM, Yen Lin CHIA, Rajendra TUMMALA, Lorin ROSKOS, Joachim ALMQUIST, Tomas ROUSE, Teodora TRASIEVA, Wendy WHITE, Dominic SINIBALDI, Madhu RAMASWAMY, Paul NEWCOMBE
  • DOSE
    Publication number: 20220340669
    Abstract: The disclosure relates to methods and compositions for the treatment of type I IFN mediated disease. Specifically, the disclosure relates to a subcutaneous dose of a type I IFN receptor inhibitor.
    Type: Application
    Filed: April 22, 2022
    Publication date: October 27, 2022
    Applicant: AstraZeneca AB
    Inventors: Catharina LINDHOLM, Yen Lin CHIA, Rajendra TUMMALA, Lorin ROSKOS, Joachim ALMQUIST, Tomas ROUSE
  • ANTI-B7-H1 ANTIBODIES FOR TREATING TUMORS
    Publication number: 20210171639
    Abstract: Provided herein are methods of treating B7-H1-expressing tumors comprising administering an effective amount of MEDI4736 or an antigen-binding fragment thereof.
    Type: Application
    Filed: October 16, 2020
    Publication date: June 10, 2021
    Inventors: RAJESH NARWAL, DAVID FAIRMAN, PAUL ROBBINS, MEINA LIANG, AMY SCHNEIDER, CARLOS CHAVEZ, CARINA HERL, MIN PAK, HONG LU, MARLON REBELATTO, KEITH STEELE, ANMARIE BOUTRIN, LI SHI, SHENGYAN HONG, BRANDON HIGGS, LORIN ROSKOS
  • Anti-B7-H1 antibodies for treating tumors
    Patent number: 10829557
    Abstract: Provided herein are methods of treating B7-H1-expressing tumors comprising administering an effective amount of MEDI4736 or an antigen-binding fragment thereof.
    Type: Grant
    Filed: May 21, 2019
    Date of Patent: November 10, 2020
    Assignee: MEDIMMUNE LIMITED
    Inventors: Rajesh Narwal, David Fairman, Paul Robbins, Meina Liang, Amy Schneider, Carlos Chavez, Carina Herl, Min Pak, Hong Lu, Marlon Rebelatto, Keith Steele, Anmarie Boutrin, Li Shi, Shengyan Hong, Brandon Higgs, Lorin Roskos
  • METHODS FOR DETERMINING TREATMENT FOR CANCER PATIENTS
    Publication number: 20200191792
    Abstract: Methods for determining treatments for cancer patients are disclosed.
    Type: Application
    Filed: October 18, 2019
    Publication date: June 18, 2020
    Inventors: LI YU, HARRY YANG, MOHAMMED DAR, LORIN ROSKOS, JEAN-CHARLES SORIA, CHARLES FERTE, WEI ZHAO, ALINE GENDRIN BROKMANN, JOLYON FARIA, PRALAY MUKHOPADHYAY
  • Methods For Treating Chronic Obstructive Pulmonary Disease Using Benralizumab
    Publication number: 20200123262
    Abstract: Provided herein is are methods of treating Chronic Obstructive Pulmonary Disease (COPD) in a patient, comprising administering to the patient an effective amount of benralizumab or an antigen-binding fragment thereof.
    Type: Application
    Filed: May 24, 2019
    Publication date: April 23, 2020
    Inventors: Rene van der Merwe, Christine Ward, Ubaldo Martin, Lorin Roskos, Bing Wang
  • METHODS FOR DETERMINING TREATMENT FOR CANCER PATIENTS
    Publication number: 20200126636
    Abstract: Methods for determining treatments for cancer patients are disclosed.
    Type: Application
    Filed: October 18, 2019
    Publication date: April 23, 2020
    Inventors: LI YU, HARRY YANG, MOHAMMED DAR, LORIN ROSKOS, JEAN-CHARLES SORIA, CHARLES FERTE, WEI ZHAO, ALINE GENDRIN BROKMANN, JOLYON FARIA, PRALAY MUKHOPADHYAY
  • ANTI-B7-H1 ANTIBODIES FOR TREATING TUMORS
    Publication number: 20190338033
    Abstract: Provided herein are methods of treating B7-H1-expressing tumors comprising administering an effective amount of MEDI4736 or an antigen-binding fragment thereof.
    Type: Application
    Filed: May 21, 2019
    Publication date: November 7, 2019
    Inventors: Rajesh Narwal, David Fairman, Paul Robbins, Meina Liang, Amy Schneider, Carlos Chavez, Carina Herl, Min Pak, Hong Lu, Marlon Rebelatto, Keith Steele, Anmarie Boutrin, Li Shi, Shengyan Hong, Brandon Higgs, Lorin Roskos
  • Anti-B7-H1 antibodies for treating tumors
    Patent number: 10336823
    Abstract: Provided herein are methods of treating B7-H1-expressing tumors comprising administering an effective amount of MEDI4736 or an antigen-binding fragment thereof.
    Type: Grant
    Filed: September 11, 2014
    Date of Patent: July 2, 2019
    Assignee: MedImmune Limited
    Inventors: Rajesh Narwal, David Fairman, Paul Robbins, Meina Liang, Amy Schneider, Carlos Chavez, Carina Herl, Min Pak, Hong Lu, Marlon Rebelatto, Keith Steele, Anmarie Boutrin, Li Shi, Shengyan Hong, Brandon Higgs, Lorin Roskos
  • Methods For Treating Chronic Obstructive Pulmonary Disease Using Benralizumab
    Publication number: 20180291108
    Abstract: Provided herein is are methods of treating Chronic Obstructive Pulmonary Disease (COPD) in a patient, comprising administering to the patient an effective amount of benralizumab or an antigen-binding fragment thereof.
    Type: Application
    Filed: November 29, 2017
    Publication date: October 11, 2018
    Inventors: Rene van der Merwe, Christine Ward, Ubaldo Martin, Lorin Roskos, Bing Wang
  • METHODS FOR REDUCING EXACERBATION RATES OF ASTHMA USING BENRALIZUMAB
    Publication number: 20170198049
    Abstract: Provided herein is are methods of reducing exacerbations of asthma in an asthma patient, comprising administering to the patient an effective amount of the anti-interleukin-5 receptor (IL-5R) antibody benralizumab or an antigen-binding fragment thereof.
    Type: Application
    Filed: September 2, 2016
    Publication date: July 13, 2017
    Inventors: Christine Ward, Lorin Roskos, Bing Wang, Donald Raible
  • METHODS FOR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASE USING BENRALIZUMAB
    Publication number: 20170107291
    Abstract: Provided herein is are methods of treating Chronic Obstructive Pulmonary Disease (COPD) in a patient, comprising administering to the patient an effective amount of benralizumab or an antigen-binding fragment thereof.
    Type: Application
    Filed: May 31, 2016
    Publication date: April 20, 2017
    Inventors: Rene van der Merwe, Christine Ward, Ubaldo Martin, Lorin Roskos, Bing Wang
  • Fixed dosage regimens for anti-type I interferon receptor (IFNAR) antibodies
    Patent number: 9493570
    Abstract: The disclosure provides methods for treating a subject having a type I IFN-mediated disease or disorder comprising administration of a fixed does of an anti-interferon alpha receptor antibody. The disclosure also provides methods for suppressing a type I interferon (IFN) gene signature (GS) in a subject. In addition, the disclosure provides methods of prognosing or monitoring disease progression in a subject having a type I IFN-mediated disease or disorder, methods of predicting a dosage regimen, methods of identifying a candidate therapeutic agent, methods of identifying a patient as a candidate for a therapeutic agent, and methods of designating a personalized therapy.
    Type: Grant
    Filed: June 12, 2013
    Date of Patent: November 15, 2016
    Assignee: MedImmune, LLC
    Inventors: Brandon Higgs, Yihong Yao, Bing Wang, Lorin Roskos, Linda Chang
  • Methods for improving asthma symptoms using benralizumab
    Patent number: 9441047
    Abstract: Provided herein are methods of improving asthma symptoms, e.g., as measured by an asthma control questionnaire, comprising administering to the patient an effective amount of benralizumab or an antigen-binding fragment thereof.
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: September 13, 2016
    Assignee: ASTRAZENECA AB
    Inventors: Christine Ward, Lorin Roskos, Bing Wang, Donald Raible
  • Methods for reducing exacerbation rates of asthma using benralizumab
    Patent number: 9441037
    Abstract: Provided herein is are methods of reducing exacerbations of asthma in an asthma patient, comprising administering to the patient an effective amount of the anti-interleukin-5 receptor (IL-5R) antibody benralizumab or an antigen-binding fragment thereof.
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: September 13, 2016
    Assignee: ASTRAZENECA AB
    Inventors: Christine Ward, Lorin Roskos, Bing Wang, Donald Raible