Patents by Inventor Lother Hennighausen

Lother Hennighausen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression of a heterologous polypeptide in mammary tissue of transgenic non-human mammals using a long whey acidic protein promoter
    Patent number: 5831141
    Abstract: Heterologous polypeptides are produced in the milk of transgenic non-human mammals by the expression of a stably integrated DNA sequence containing the long whey acidic protein promoter operably linked to a DNA sequence encoding a heterologous polypeptide and a signal sequence. The transgenic non-human mammals of the present invention are produced by introducing this DNA sequence such that the DNA sequence is stably integrated into the DNA of germ line cells of the mature mammal and inherited in normal Mendelian fashion. A representative heterologous polypeptide is protein C.
    Type: Grant
    Filed: September 10, 1992
    Date of Patent: November 3, 1998
    Assignees: United States of America as represented by the Department of Health and Human Services, American Red Cross
    Inventors: Henryk Lubon, William N. Drohan, Lother Hennighausen