Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR6 or N; Y is CR3 or N; R1, R2, R3, R4, R5, R6, R7, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.

Abstract: Apparatus for cutting a circular hole in a workpiece having relatively low compression strength, including a hollow cylindrical drill having, at its outer terminal end, an annular cutting edge of a predetermined diameter for cutting a hole in the object. The drill includes a cylindrical wall having an axially inwardly converging sidewall portion for radially compressing the material severed from the object being cut and an inner cylindrical throat portion of a predetermined axial length and a predetermined reduced diameter for forming a continuous core of severed material. The cylindrical wall includes a tubular discharge section, axially inward of the throat and communicating with an open outlet end of the tubular member, to allow the compressed core to partially radially expand and freely axially pass. The diameter of the discharge tubular section is greater than the diameter of the throat portion but less than the diameter of the annular cutting edge.