Abstract: The present invention describes stem cells and progenitor cells derived from hemangiomas, including testing of angiogenic inhibitors using these cells. The invention as described is useful in providing a process to culture and propagate hemangioma stem cells and generate xenograft models to develop treatments for infantile hemangiomas and other types of vascular lesions.

Abstract: The present invention describes stem cells and progenitor cells derived from hemangiomas, including testing of angiogenic inhibitors using these cells. The invention as described is useful in providing a process to culture and propagate hemangioma stem cells and generate xenograft models to develop treatments for infantile hemangiomas and other types of vascular lesions.

Abstract: The present invention discloses statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) consistently and significantly increased endothelial cell thrombomodulin protein and functional activity. Statins also abrogated the downregulation of thrombomodulin that occurs in response to radiation injury. These results indicate that preserving or restoring endothelial thrombomodulin expression and function by statins may be useful in a variety of disorders associated with widespread endothelial dysfunction such as sepsis, adult respiratory distress syndrome, and normal tissue radiation injury.

Abstract: The present invention describes stem cells and progenitor cells derived from hemangiomas, including testing of angiogenic inhibitors using these cells. The invention as described is useful in providing a process to culture and propagate hemangioma stem cells and generate xenograft models to develop treatments for infantile hemangiomas and other types of vascular lesions.

Abstract: The present invention provides a method of reducing intraocular fibrin comprising the administration of a pharmacologically effective dose of Protein C to an individual having elevated levels of intraocular fibrin. Also provided are various methods of preventing intraocular fibrin formation, treating intraocular diseases and reducing intraocular inflammation.

Abstract: An apparatus for the placement and monitoring of the position of an intraluminal indwelling catheter using an infrared (IR) signal encoded in the catheter and the detection of the IR signal by an IR optical detector. The IR signal may be encoded into the catheter by IR emitted from the catheter or IR reflected from the catheter. In the first category, the catheter is illuminated by IR radiation emitted from the distal end of the catheter, either by fiber optics or by a micro-diode. In the second category, the catheter is marked with regions of varying optical properties to form a pattern that is easily visualized and distinctive from nearby anatomical structures. One embodiment has a helical pattern in either one or more solid bands or a series of helically arranged dots. Other embodiments employ a pair of criss-crossing helical bands or zebra stripes. In addition to IR radiation, other electromagnetic radiation, including visible light, may be used.

Abstract: The present invention provides a method of reducing intraocular fibrin comprising the administration of a pharmacologically effective dose of Protein C to an individual having elevated levels of intraocular fibrin. Also provided are various methods of preventing intraocular fibrin formation, treating intraocular diseases and reducing intraocular inflammation.

Abstract: An apparatus for the placement and monitoring of the position of an intraluminal indwelling catheter using an infrared (IR) signal encoded in the catheter and the detection of the IR signal by an IR optical detector. The IR signal may be encoded into the catheter by IR emitted from the catheter or IR reflected from the catheter. In the first category, the catheter is illuminated by IR radiation emitted from the distal end of the catheter, either by fiber optics or by a micro-diode. In the second category, the catheter is marked with regions of varying optical properties to form a pattern that is easily visualized and distinctive from nearby anatomical structures. One embodiment has a helical pattern in either one or more solid bands or a series of helically arranged dots. Other embodiments employ a pair of crisscrossing helical bands or zebra stripes. In addition to IR radiation, other electromagnetic radiation, including visible light, may be used.

Abstract: An apparatus for the placement and monitoring of the position of an intraluminal indwelling catheter using an infrared (IR) signal encoded in the catheter and the detection of the IR signal by an IR optical detector. The IR signal may be encoded into the catheter by IR emitted from the catheter or IR reflected from the catheter. In the first category, the catheter is illuminated by IR radiation emitted from the distal end of the catheter, either by fiber optics or by a micro-diode. In the second category, the catheter is marked with regions of varying optical properties to form a pattern that is easily visualized and distinctive from nearby anatomical structures. One embodiment has a helical pattern in either one or more solid bands or a series of helically arranged dots. Other embodiments employ a pair of criss-crossing helical bands or zebra stripes. In addition to IR radiation, other electromagnetic radiation, including visible light, may be used.

Abstract: An apparatus and method for the electrodeposition of microorganisms on an electrode using a weak, direct current voltage. The electrodeposition of the microorganisms occurs within a relatively short period of time thereby reducing the requirement for culturing the microorganisms. The electrode can be used as an electrode for a Curie point pyrolysis mass spectrometer to determine the specific microorganism electrodeposited on the electrode.