Abstract: A stent may include a radially expandable tubular framework includes a first end region, a second end region, a medial region positioned between the first end region and the second end region, and a lumen extending therethrough. The radially expandable tubular framework is configured to expand from a radially collapsed configuration to a radially expanded configuration. A plurality of covering strips are positioned along at least one of the first end region, the medial region, and the second end region. The plurality of covering strips fully covering the radially expandable tubular framework in the radially collapsed configuration, and the plurality of covering strips are configured to separate from one another in the radially expanded configuration to expose portions of the radially expandable tubular framework therebetween.

Abstract: The present disclosure relates to the field of medical devices. Specifically, the present disclosure relates to devices, systems and methods for extending a working channel of an endoscope, such as for delivery of a stent.

Abstract: A system for maintaining patency of a body lumen may include a first endoprosthesis configured to shift from a straightened configuration to a helical configuration defining a plurality of loops, and a second endoprosthesis configured to shift from a radially collapsed configuration toward a radially expanded configuration. The plurality of loops defines a passage having an inner diameter. At least a portion of the second endoprosthesis is disposed within the passage in the radially expanded configuration. A method of maintaining patency of a body lumen may include advancing a first endoprosthesis into a first body lumen in a straightened configuration, deploying the first endoprosthesis within the first body lumen in a helical configuration defining a plurality of loops, advancing a second endoprosthesis into the first body lumen in a radially collapsed configuration, and shifting the second endoprosthesis to a radially expanded configuration within the plurality of loops.

Abstract: The present disclosure relates generally to the field of medical devices for accessing body lumens. In particular, the present disclosure relates to medical devices, systems and methods for enlarging an opening of a body lumen. In an embodiment, a device may include a flexible elongate tube. A distal end of the tube may be configured to access an opening of a body lumen. A plurality of wire lumens may extend from the distal end of the tube toward a proximal end of the tube that are radially offset from and substantially parallel with a longitudinal axis. At least a portion of the plurality of wire lumens may be exposed to an outer surface of the tube along a distal portion. A plurality of wires may each extend along a respective wire lumen. A portion of each wire may extend externally to the wire lumens exposed to the outer surface.

Abstract: A lumen-apposing access system may include a catheter and a cauterization tip. The cauterization tip may include a biasing member and a cautery element. The cauterization tip may move relative to the catheter between a first position in which the cautery element is electrically inactive, and a second position in which the cautery element is electrically active. The biasing member biases the cautery element in the first position.

Abstract: An esophageal stent may include an expandable framework having a first end, a second end, and a central longitudinal axis extending from the first end to the second end, the expandable framework being configured to expand from a radially collapsed configuration to a radially expanded configuration, and a polymeric outer sleeve disposed radially outward of and spaced apart from a body region of the expandable framework. The expandable framework may include a plurality of anti-migration supports extending radially outward from the body region of the expandable framework toward the polymeric outer sleeve.

Abstract: An illustrative stent includes an elongated tubular member comprising at least one strut or filament forming a tubular wall having a plurality of cells extending through a thickness of the tubular wall. The elongated tubular member may be configured to move between a radially collapsed configuration and a radially expanded configuration. A coating is disposed on the elongated tubular member and spanning the plurality of cells. The coating forms a pocket within at least some of the cells of the plurality of cells and extends radially inward of the tubular wall to define a void. In some instances, a partition or wall is positioned within at least some of the pockets and transects the void.

Abstract: A lumen-apposing access system may include a catheter and a cauterization tip. The cauterization tip may include a biasing member and a cautery element. The cauterization tip may move relative to the catheter between a first position in which the cautery element is electrically inactive, and a second position in which the cautery element is electrically active. The biasing member biases the cautery element in the first position.

Abstract: An esophageal stent may include an expandable framework having a first end, a second end, and a central longitudinal axis extending from the first end to the second end, the expandable framework being configured to expand from a radially collapsed configuration to a radially expanded configuration, and a polymeric outer sleeve disposed radially outward of and spaced apart from a body region of the expandable framework. The expandable framework may include a plurality of anti-migration supports extending radially outward from the body region of the expandable framework toward the polymeric outer sleeve.

Abstract: A medical instrument may include a tube, a sheath provided around and coaxial with the tube, and an inflatable balloon at a distal end of the sheath. The balloon may receive a fluid from a lumen of the sheath, and may have a central opening along a longitudinal axis thereof, and into which the tube extends, a proximal portion, a middle portion adjacent to and distal of the proximal portion, and a distal portion adjacent to and proximal of the middle portion. When the balloon is inflated with the fluid, a maximum diameter of the middle portion may be less than a maximum diameter of the proximal portion, and less than a maximum diameter of the distal portion. The medical instrument may also include an extraction member provided at a distal end of the tube, distal to the balloon, and movable axially relative to the balloon.

Abstract: An illustrative stent includes an elongated tubular member comprising at least one strut or filament forming a tubular wall having a plurality of cells extending through a thickness of the tubular wall. The elongated tubular member may be configured to move between a radially collapsed configuration and a radially expanded configuration. A coating is disposed on the elongated tubular member and spanning the plurality of cells. The coating forms a pocket within at least some of the cells of the plurality of cells and extends radially inward of the tubular wall to define a void. In some instances, a partition or wall is positioned within at least some of the pockets and transects the void.

Abstract: The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to devices and methods for controlled delivery of a stent, such as a self-expanding stent, and more particularly for controlling the full deployment of a stent in incremental steps from a sheath and for controlling the reconstrainment of a stent in incremental steps within a sheath.

Abstract: The present disclosure relates generally to stents and methods for managing passage of material through a body lumen. In some embodiments, a medical stent may include a stent body defined by a hollow tubular elongate structure extending along a central axis, the stent body including a first portion and a second portion. The medical stent may further include a control region between the first and second portions, wherein in a first configuration the hollow tubular elongate structure of the control region is in a closed, twisted configuration, and wherein in a second configuration the hollow tubular elongate structure of the control region is in an open, expanded configuration.

Abstract: An illustrative stent may comprise an elongated tubular member having a longitudinal axis, the elongated tubular member comprising at least one knitted filament forming a plurality of twisted knit stitches with intermediate rung portions extending circumferentially between radially adjacent twisted knit stitches. Each twisted knit stitch may be interconnected with a longitudinally adjacent twisted knit stitch forming a series of linked stitches. The elongated tubular member may be configured to move between a collapsed configuration and an expanded configuration, wherein in the collapsed configuration the series of linked stitches form longitudinal columns and in the expanded configuration the series of linked stitches extend helically around the elongated tubular member.

Abstract: The present disclosure relates to the field of medical devices. Specifically, the present disclosure relates to devices, systems and methods for extending a working channel of an endoscope, such as for delivery of a stent.

Abstract: The present disclosure relates generally to stents and methods for managing passage of material through a body lumen. In some embodiments, a medical stent may include a stent body defined by a hollow tubular elongate structure extending along a central axis, the stent body including a first portion and a second portion. The medical stent may further include a control region between the first and second portions, wherein in a first configuration the hollow tubular elongate structure of the control region is in a closed, twisted configuration, and wherein in a second configuration the hollow tubular elongate structure of the control region is in an open, expanded configuration.

Abstract: The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to devices and methods for controlled delivery of a stent, such as a self-expanding stent, and more particularly for controlling the full deployment of a stent in incremental steps from a sheath and for controlling the reconstrainment of a stent in incremental steps within a sheath.

Abstract: An illustrative stent may comprise an elongated tubular member having a longitudinal axis, the elongated tubular member comprising at least one knitted filament forming a plurality of twisted knit stitches with intermediate rung portions extending circumferentially between radially adjacent twisted knit stitches. Each twisted knit stitch may be interconnected with a longitudinally adjacent twisted knit stitch forming a series of linked stitches. The elongated tubular member may be configured to move between a collapsed configuration and an expanded configuration, wherein in the collapsed configuration the series of linked stitches form longitudinal columns and in the expanded configuration the series of linked stitches extend helically around the elongated tubular member.

Abstract: A system and method for delivering irreversible electroporation treatment to a selected tissue includes introducing an endoscope into a position adjacent the selected tissue, and advancing first and second probes having electrodes at their distal ends. One probe may be inserted into the lesion or tumor and remain in place while the other probe is moved around the tumor, with activation of the electrodes occurring at each location of the probes.

Abstract: A device for occluding flow of materials is formed as a simple structure permitting a compact delivery configuration which may shift to an expanded deployment configuration. The device has at least one expandable portion formed of a plurality of elongated longitudinally extending frame elements. The frame elements may be spaced apart to define spaces therebetween, and a flexible occlusive material may be provided to block flow of material through such spaces. A flexible occlusive material may form one of two expandable portions of the device without the need for frame elements.