Patents by Inventor Lowell D. Markley
Lowell D. Markley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10913737Abstract: Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to imidazopyridine compounds, synthesis thereof, and methods of using same. Disclosed herein are various imidazo[1,2-a]pyhdine compounds and methods of using the novel compounds to treat or prevent tuberculosis in a subject or to inhibit fungal growth on plant species. Other embodiments include methods of synthesizing imidazo[1,2-a]pyridine compounds, such as the disclosed imidazo[1,2-a]pyridine compounds.Type: GrantFiled: February 5, 2018Date of Patent: February 9, 2021Assignee: UNIVERSITY OF NOTRE DAME DU LACInventors: Marvin J. Miller, Garrett C. Moraski, Lowell D. Markley, George E. Davis
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Publication number: 20180354944Abstract: Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to imidazopyridine compounds, synthesis thereof, and methods of using same. Disclosed herein are various imidazo[1,2-a]pyhdine compounds and methods of using the novel compounds to treat or prevent tuberculosis in a subject or to inhibit fungal growth on plant species. Other embodiments include methods of synthesizing imidazo [1,2-a]pyridine compounds, such as the disclosed imidazo[1,2-a]pyridine compounds.Type: ApplicationFiled: February 5, 2018Publication date: December 13, 2018Applicant: UNIVERSITY OF NOTRE DAME DU LACInventors: Marvin J. MILLER, Garrett C. MORASKI, Lowell D. MARKLEY, George E. DAVIS
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Patent number: 9908876Abstract: Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to imidazopyridine compounds, synthesis thereof, and methods of using same. Disclosed herein are various imidazo[1,2-a]pyhdine compounds and methods of using the novel compounds to treat or prevent tuberculosis in a subject or to inhibit fungal growth on plant species. Other embodiments include methods of synthesizing imidazo[1,2-a]pyridine compounds, such as the disclosed imidazo[1,2-a]pyridine compounds.Type: GrantFiled: February 29, 2016Date of Patent: March 6, 2018Assignee: UNIVERSITY OF NOTRE DAME DU LACInventors: Marvin J. Miller, Garrett C. Moraski, Lowell D. Markley, George E. Davis
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Publication number: 20160318925Abstract: Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to imidazopyridine compounds, synthesis thereof, and methods of using same. Disclosed herein are various imidazo[1,2-a]pyhdine compounds and methods of using the novel compounds to treat or prevent tuberculosis in a subject or to inhibit fungal growth on plant species. Other embodiments include methods of synthesizing imidazo[1,2-a]pyridine compounds, such as the disclosed imidazo[1,2-a]pyridine compounds.Type: ApplicationFiled: February 29, 2016Publication date: November 3, 2016Applicant: UNIVERSITY OF NOTRE DAME DU LACInventors: Marvin J. MILLER, Garrett C. MORASKI, Lowell D. MARKLEY, George E. DAVIS
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Patent number: 9309238Abstract: Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to imidazopyridine compounds, synthesis thereof, and methods of using same. Disclosed herein are various imidazo[1,2-a]pyhdine compounds and methods of using the novel compounds to treat or prevent tuberculosis in a subject or to inhibit fungal growth on plant species. Other embodiments include methods of synthesizing imidazo[1,2-a]pyridine compounds, such as the disclosed imidazo[1,2-a]pyridine compounds.Type: GrantFiled: November 5, 2010Date of Patent: April 12, 2016Assignee: UNIVERSITY OF NOTRE DAME DU LACInventors: Marvin J. Miller, Garrett C. Moraski, Lowell D. Markley, George E. Davis
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Publication number: 20120220457Abstract: Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to imidazopyridine compounds, synthesis thereof, and methods of using same. Disclosed herein are various imidazo[1,2-a]pyhdine compounds and methods of using the novel compounds to treat or prevent tuberculosis in a subject or to inhibit fungal growth on plant species. Other embodiments include methods of synthesizing imidazo [1,2- a]pyridine compounds, such as the disclosed imidazo[1,2-a]pyridine compounds.Type: ApplicationFiled: November 5, 2010Publication date: August 30, 2012Applicants: Dow AgroSciences LLC, University of Notre Dame du LacInventors: Marvin J. Miller, Garrett C. Moraski, Lowell D. Markley, George E. Davis
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Patent number: 5780465Abstract: 4-Substituted 5-polycyclylpyrimidine compounds in which the 5-substituent is polycyclic and is attached to the pyrimidine moiety through an aliphatic carbon atom, such as 5-(2,2-dimethylindan-1-yl)-4-methylthiopyrimidine, were prepared and found to possess excellent herbicidal activity. The compounds are especially useful for the control of undesirable vegetation in paddy rice.Type: GrantFiled: April 3, 1997Date of Patent: July 14, 1998Assignee: Dow AgroSciences LLCInventors: Lowell D. Markley, Kim E. Arndt, Patricia G. Ray, Terry W. Balko, Erik N. K. Cressman, David G. Ouse, Johnny L. Jackson, Jacob Secor
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Patent number: 5399542Abstract: The present disclosure is directed to substituted cyclohexanedione compounds, the preparation of said compounds, compositions containing said compounds and the use of said compositions in the selective pre- and postemergent kill and control of grassy weeds in the presence of various broad-leafed and grassy crop plants.Type: GrantFiled: December 20, 1993Date of Patent: March 21, 1995Assignee: DowElancoInventors: Christopher T. Hamilton, Lowell D. Markley, Todd C. Geselius
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Patent number: 5013352Abstract: The present disclosure is directed to substituted cyclohexanedione compounds, the preparation of said compounds, compositions containing said compounds and the use of said compositions in the selective pre- and postemergent kill and control of grassy weeds in the presence of various crop plants.Type: GrantFiled: March 30, 1990Date of Patent: May 7, 1991Assignee: DowElancoInventors: Lowell D. Markley, Christopher T. Hamilton, Beth A. Swisher, Jacob Secor
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Patent number: 5006159Abstract: The present disclosure is directed to substituted cyclohexanedione compounds, the preparation of said compounds, compositions containing said compounds and the use of said compositions in the selective pre- and postemergent kill and control of grassy weeds in the presence of various crop plants.Type: GrantFiled: March 30, 1990Date of Patent: April 9, 1991Assignee: DowElancoInventors: Lowell D. Markley, Christopher T. Hamilton, Beth A. Swisher, Jacob Secor
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Patent number: 4983211Abstract: The present disclosure is directed to substituted cyclohexanedione compounds, the preparation of said compounds, compositions containing said compounds and the use of said compositions in the selective pre- and postemergent kill and control of grassy weeds in the presence of various crop plants.Type: GrantFiled: March 30, 1990Date of Patent: January 8, 1991Assignee: DowElancoInventors: Lowell D. Markley, Christopher T. Hamilton, Beth A. Swisher, Jacob Secor
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Patent number: 4935436Abstract: Substituted triazole compounds, their preparation, compositions containing said compounds and the use of said compositions to control fungal infections in plants are disclosed.Type: GrantFiled: January 23, 1989Date of Patent: June 19, 1990Assignee: The Dow Chemical CompanyInventors: Lowell D. Markley, Richard B. Rogers, Neil V. Kirby, John W. Liebeschuetz, Peter F. S. Street
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Patent number: 4927833Abstract: Substituted azole compounds especially substituted imidazole and triazole compounds, their preparation, compositions containing said compounds and the use of said compositions to control fungal infections in plants are disclosed.Type: GrantFiled: January 23, 1989Date of Patent: May 22, 1990Assignee: The Dow Chemical CompanyInventors: Neil V. Kirby, Peter F. S. Street, Lowell D. Markley
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Patent number: 4824475Abstract: The herbicidal action of a herbicidal triazine upon weeds is enchanced upon also applying to the weeds a second herbicidal component, a butyl or pentyl glycol sulfonate or glycol sulfamate having 3, 5 or 3 substituted phenyl in the 2-position of the butyl or pentyl chain. The glycol sulfonate or sulfamate also adds its own herbicidal action to increase effectiveness.Both components are applied simultaneously as a novel composition which may also contain crop oil or crop oil concentrate. Application is made post-emergently before weeds reach about the 8 leaf stage. Advantageously, in an additional step, triazine alone or in combination with at least some of the sulfonate or sulfamate is also applied at planting or very early postemergently prior to the treatment described.Type: GrantFiled: September 16, 1985Date of Patent: April 25, 1989Assignee: The Dow Chemical CompanyInventors: Lowell D. Markley, Paul S. Zorner
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Patent number: 4505929Abstract: Novel compounds exhibiting antiviral activity are disclosed, such compounds are represented by the formula: ##STR1## wherein m represents the integer 0, 1 or 2; R represents trihalomethyl, alkyl or phenyl; R.sub.1 represents hydrogen, bromo, chloro, fluoro, cyano, nitro, amino, alkyl, alkoxy or trifluoromethyl; R.sub.2 represents hydroxyl, bromo, chloro, fluoro, cyano, acetyl, benzoyl, substituted benzoyl, alkyl, alkoxy, substituted alkoxy, benzyl, substituted benzyl, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylaminosulfonyl, dialkylaminosulfonyl, or the radical --O(CH.sub.2).sub.n R.sub.4 wherein n represents the integer 1, 2 or 3 and R.sub.4 represents cyano or dialkylamino; R.sub.3 represents hydrogen, hydroxyl, bromo, chloro, fluoro, cyano, acetyl, benzoyl, substituted benzoyl, alkyl, alkoxy, substituted alkoxy, benzyl, substituted benzyl, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylaminosulfonyl, dialkylaminosulfonyl, or the radical --O(CH.sub.2).sub.n R.sub.Type: GrantFiled: August 16, 1982Date of Patent: March 19, 1985Assignee: The Dow Chemical CompanyInventors: Lowell D. Markley, Yulan C. Tong, Steven G. Wood
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Patent number: 4474602Abstract: Substituted pyridyl compounds, e.g. 2,6-dichloro-4(2-(2,2,2-trichloroethyl)oxiranyl) pyridine; herbicidal compositions containing such compounds and method for the control of undesired vegetation using these compositions.Type: GrantFiled: January 19, 1982Date of Patent: October 2, 1984Assignee: The Dow Chemical CompanyInventors: Lowell D. Markley, John M. Soper
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Patent number: 4371537Abstract: Sulfur-substituted phenoxypyridines having antiviral activity are disclosed. Methods of using the sulfur-substituted phenoxypyridines to employ their antiviral activity are also disclosed as well as pharmaceutically-acceptable compositions thereof.Type: GrantFiled: August 13, 1981Date of Patent: February 1, 1983Assignee: The Dow Chemical CompanyInventors: Lowell D. Markley, Yulan C. Tong, Steven G. Wood
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Patent number: 4349568Abstract: Novel compounds exhibiting antiviral activity are disclosed, such compounds are represented by the formula: ##STR1## wherein m represents the integer 0, 1 or 2; R represents trihalomethyl, alkyl or phenyl; R.sub.1 represents hydrogen, bromo, chloro, fluoro, cyano, nitro, amino, alkyl, alkoxy or trifluoromethyl; R.sub.2 represents hydroxyl, bromo, chloro, fluoro, cyano, acetyl, benzoyl, substituted benzoyl, alkyl, alkoxy, substituted alkoxy, benzyl, substituted benzyl, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylaminosulfonyl, dialkylaminosulfonyl, or the radical --O(CH.sub.2).sub.n R.sub.4 wherein n represents the integer 1, 2 or 3 and R.sub.4 represents cyano or dialkylamino; R.sub.3 represents hydrogen, hydroxyl, bromo, chloro, fluoro, cyano, acetyl, benzoyl, substituted benzoyl, alkyl, alkoxy, substituted alkoxy, benzyl, substituted benzyl, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylaminosulfonyl, dialkylaminosulfonyl, or the radical --O(CH.sub.2).sub.n R.sub.Type: GrantFiled: June 12, 1980Date of Patent: September 14, 1982Assignee: The Dow Chemical CompanyInventors: Lowell D. Markley, Yulan C. Tong, Steven G. Wood
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Patent number: 4332820Abstract: Substituted benzonitriles having antiviral activity are disclosed. Methods of use based on the antiviral activity of the compounds are also disclosed, as well as compositions which comprise a carrier in combination with a suitable antiviral active compound.Type: GrantFiled: December 29, 1980Date of Patent: June 1, 1982Assignee: The Dow Chemical CompanyInventor: Lowell D. Markley
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Patent number: 4254144Abstract: Substituted benzonitriles are disclosed having the formula ##STR1## wherein X represents O or S; R.sub.1 represents bromo, chloro, fluoro, phenoxy, loweralkylthio, loweralkylsulfinyl, loweralkylsulfonyl, loweralkylaminosulfonyl, diloweralkylaminosulfonyl or benzoyl; and R.sub.2 represents hydrogen, bromo, chloro or fluoro with the proviso that R.sub.2 is hydrogen when R.sub.1 is a substituent other than bromo, chloro or fluoro. The compounds of the invention exhibit antiviral activity. Methods of use based on the antiviral activity of the compounds are also disclosed, as well as compositions which comprise a carrier in combination with a suitable antiviral active compound.Type: GrantFiled: January 25, 1980Date of Patent: March 3, 1981Assignee: The Dow Chemical CompanyInventor: Lowell D. Markley