Patents by Inventor Lu Ang XU

Lu Ang XU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of inhibiting cell proliferation and METTL8 activity
    Patent number: 11642362
    Abstract: The disclosure provides a method of inhibiting proliferation of a cell, inhibiting m3C formation in a cell, inhibiting activity of Mettl8 in a cell, or activating ATM and p53 in a cell, the method comprising contacting the cell with a Mettl8 inhibitor. The disclosure also provides a composition comprising a cell with a reduced expression or activity of Mettl8. In another aspect, the disclosure provides methods of rendering a tumor cell sensitive to a cancer therapy.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: May 9, 2023
    Assignee: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Xin-Yuan Fu, Xinyu Liu, Lu Ang Xu
  • METHODS OF INHIBITING CELL PROLIFERATION AND METTL8 ACTIVITY
    Publication number: 20200222444
    Abstract: The disclosure provides a method of inhibiting proliferation of a cell, inhibiting m3C formation in a cell, inhibiting activity of Mettl8 in a cell, or activating ATM and p53 in a cell, the method comprising contacting the cell with a Mettl8 inhibitor. The disclosure also provides a composition comprising a cell with a reduced expression or activity of Mettl8. In another aspect, the disclosure provides methods of rendering a tumor cell sensitive to a cancer therapy.
    Type: Application
    Filed: July 6, 2018
    Publication date: July 16, 2020
    Applicant: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Xin-Yuan FU, Xinyu LIU, Lu Ang XU