Patents by Inventor Luca Carcone

Luca Carcone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of ferric organic compounds
    Patent number: 11926586
    Abstract: A highly pure form of ferric citrate and an industrially viable and advantageous process for its preparation are described.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: March 12, 2024
    Assignee: QUÍMICA SINTÉTICA, S.A.
    Inventors: Giuseppe Barreca, Luca Carcone, Norberto Masciocchi
  • SOLID FORMS OF TEZACAFTOR AND PROCESSES FOR THE PREPARATION THEREOF
    Publication number: 20230092495
    Abstract: A crystalline form of tezacaftor, an industrially viable and advantageous process for its preparation and a method for the preparation of amorphous form of tezacaftor are described.
    Type: Application
    Filed: March 5, 2021
    Publication date: March 23, 2023
    Inventors: Giuseppe BARRECA, Luca CARCONE, Marianna COPPOLA, Cristina PESENTI, Massimo ZAMPIERI, Davide BORDONE, Silvano RONZONI, Piero PARAVIDINO
  • PROCESS FOR THE PREPARATION OF FERRIC ORGANIC COMPOUNDS
    Publication number: 20220396542
    Abstract: A highly pure form of ferric citrate and an industrially viable and advantageous process for its preparation are described.
    Type: Application
    Filed: November 6, 2020
    Publication date: December 15, 2022
    Inventors: Giuseppe BARRECA, Luca CARCONE, Norberto MASCIOCCHI
  • Process for the preparation of sphingosine-1-phosphate receptor agonist
    Patent number: 11465977
    Abstract: Industrially viable and advantageous processes for the preparation of Ozanimod are described. The invention also discloses the intermediates obtained in the process.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: October 11, 2022
    Assignee: QUÍMICA SINTÉTICA, S.A.
    Inventors: Giuseppe Barreca, Luca Carcone, Maurizio Taddei, Damian Mark Grainger, Samantha Louise Staniland, Claudio Cianferotti, Giovanni Marras
  • PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST
    Publication number: 20220033365
    Abstract: Industrially viable and advantageous processes for the preparation of Ozanimod are described. The invention also discloses the intermediates obtained in the process.
    Type: Application
    Filed: September 25, 2019
    Publication date: February 3, 2022
    Applicant: QUÍMICA SINTÉTICA, S.A.
    Inventors: Giuseppe BARRECA, Luca CARCONE, Maurizio TADDEI, Damian Mark GRAINGER, Samantha Louise STANILAND, Claudio CIANFEROTTI, Giovanni MARRAS
  • Processes for the preparation of diastereomerically and enantiomerically enriched oxazolines
    Patent number: 10597353
    Abstract: The invention relates to an industrially viable and advantageous process for the preparation of (2S,3 R)-2-amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid, having the following formula (I) generally known as Droxidopa, or of intermediates useful in the synthesis thereof.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: March 24, 2020
    Assignee: QUÍMICA SINTÉTICA, S.A.
    Inventors: Giuseppe Barreca, Marcello Rasparini, Luca Carcone, Fabio Morana
  • Nucleoside phosphoramidates useful for the treatment of viral infections and preparation thereof
    Patent number: 10407456
    Abstract: Two processes are described for preparing, in different diastereomeric purity degrees, the compound (S)-isopropyl-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)-phosphoryl)amino) propanoate, having the formula given below, known as Sofosbuvir and used for the treatment of hepatitis C.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: September 10, 2019
    Assignee: QUIMICA SINTETICA, S.A.
    Inventors: Giuseppe Barreca, Marcello Rasparini, Andrea Poggiali, Luca Carcone, Roberto Rocco Tufaro, Giovanni Marras, Maurizio Taddei, Elena Cini
  • PROCESSES FOR THE PREPARATION OF DIASTEREOMERICALLY AND ENANTIOMERICALLY ENRICHED OXAZOLINES
    Publication number: 20180327349
    Abstract: The invention relates to an industrially viable and advantageous process for the preparation of (2S,3R)-2-amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid, having the following formula (I) generally known as Droxidopa, or of intermediates useful in the synthesis thereof.
    Type: Application
    Filed: November 10, 2016
    Publication date: November 15, 2018
    Inventors: Giuseppe BARRECA, Marcello RASPARINI, Luca CARCONE, Fabio MORANA
  • NUCLEOSIDE PHOSPHORAMIDATES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS AND PREPARATION THEREOF
    Publication number: 20180118776
    Abstract: Two processes are described for preparing, in different diastereomeric purity degrees, the compound (S)-isopropyl-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)-phosphoryl)amino) propanoate, having the formula given below, known as Sofosbuvir and used for the treatment of hepatitis C.
    Type: Application
    Filed: March 25, 2016
    Publication date: May 3, 2018
    Inventors: Giuseppe BARRECA, Marcello RASPARINI, Andrea POGGIALI, Luca CARCONE, Roberto Rocco TUFARO, Giovanni MARRAS, Maurizio TADDEI, Elena CINI
  • Process for producing Aliskiren
    Patent number: 9346745
    Abstract: A new route of synthesis of the compound Aliskiren of formula (I), used in the treatment of hypertension, is described.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: May 24, 2016
    Assignee: CHEMO IBERICA, S.A.
    Inventors: Maurizio Taddei, Adele Russo, Elena Cini, Renata Riva, Marcello Rasparini, Luca Carcone, Luca Banfi, Romina Vitale, Stephen Roseblade, Antonio Carlo Zanotti-Gerosa
  • Chemical process for opening ring compounds
    Patent number: 9067868
    Abstract: It is described a process for the opening of lactone or lactam rings useful in the synthesis of pharmaceutically active compounds and the intermediates thereof, particularly Aliskiren. It has found that by selecting a type of solvent it is possible to obtain excellent yields and high optical and chemical purity of the isolated products.
    Type: Grant
    Filed: July 25, 2012
    Date of Patent: June 30, 2015
    Assignee: Chemo Iberica, S.A.
    Inventors: Luca Carcone, Domenico Magrone, Giuseppe Barreca, Marcello Rasparini, Huang Liming
  • CHEMICAL PROCESS FOR OPENING RING COMPOUNDS
    Publication number: 20140213821
    Abstract: It is described a process for the opening of lactone or lactam rings useful in the synthesis of pharmaceutically active compounds and the intermediates thereof, particularly Aliskiren. It has found that by selecting a type of solvent it is possible to obtain excellent yields and high optical and chemical purity of the isolated products.
    Type: Application
    Filed: July 25, 2012
    Publication date: July 31, 2014
    Applicant: CHEMO IBERICA, S. A.
    Inventors: Luca Carcone, Domenico Magrone, Giuseppe Barreca, Marcello Rasparini, Huang Liming
  • Process for Producing Aliskiren
    Publication number: 20130071899
    Abstract: A new route of synthesis of the compound Aliskiren of formula (I), used in the treatment of hypertension, is described.
    Type: Application
    Filed: June 3, 2011
    Publication date: March 21, 2013
    Applicant: Chemo Iberica, S.A.
    Inventors: Maurizio Taddei, Adele Russo, Elena Cini, Renata Riva, Marcello Rasparini, Luca Carcone, Luca Banfi, Romina Vitale, Stephen Roseblade, Antonio Carlo Zanotti-Gerosa