Abstract: The present disclosure relates to a hydrogel fibre comprising an ionic hydrogel and a second component in a plurality of compartments, wherein the second component is selected from a second hydrogel, a hydrophilic solution, or a mixture thereof. It is also disclosed the method to obtain the aforesaid hydrogel fibres. This disclosure also relates to a composition comprising the hydrogel fibres and a suitable carrier, and an article/kit, a bundle, a mesh or a membrane comprising the hydrogel fibre. A composition comprising an ionic hydrogel and a second component for use in medicine administered in a hydrogel fibre comprising a plurality of compartments is also disclosed.

Abstract: The present disclosure relates to a composition for the use in the fields of cancer, immunotherapy and biotechnology. Particularly it relates to the field of gellan gum hydrogel-like particles for artificial antigen presentation in immunotherapy.

Abstract: The present application discloses a method to produce fibers with different segments along the major axis. The different segments can be constituted of the same materials that entrap different objects (molecules, particles) or can be made of different materials. The different segments are made thanks to a junction and by alternating the dispensing of such materials using different inlet channels. This method allows the production of fibers that can be used as processed or after being further manipulated by other processes, as single devices or as building blocks to construct devices that are more complex. Fibers with different segments along the axis can be exploited for a wide range of applications as medical devices and/or as drug delivery system and/or as matrices to be used for acellular tissue regeneration and cellular tissue engineering/regenerative medicine strategies and/or as supports for imaging in high throughput screening.

Abstract: A structure of calorimeter provides a calorimetric head (1) comprising a calorimetric cell (10) suitable for receiving a sample holding container (20) containing a sample (25) to examine. The cell (10) is arranged according to a first shield (3), or active shield. Outside the active shield (3) a second shield (4), or dynamical shield is present, which comprises a cylindrical hollow body arranged around the active shield (3) for all its length in order to provide a space (5) of determined size. Outside the active shield a thermal bath is present (not shown) at a temperature lower than the first and the second shield (3,4). The dynamic shield (4) allows an effective adjustment of the heat flux through the active shield (3) during calorimetric measures by limiting the heat flux same. In fact, in operative conditions the dynamic shield acts as thermal flywheel and keeps constant the heat flux coming from the active shield (3).

Abstract: A structure of calorimeter provides a calorimetric head (1) comprising a calorimetric cell (10) suitable for receiving a sample holding container (20) containing a sample (25) to examine. The cell (10) is arranged according to a first shield (3), or active shield. Outside the active shield (3) a second shield (4), or dynamical shield is present, which comprises a cylindrical hollow body arranged around the active shield (3) for all its length in order to provide a space (5) of determined size. Outside the active shield a thermal bath is present (not shown) at a temperature lower than the first and the second shield (3,4). The dynamic shield (4) allows an effective adjustment of the heat flux through the active shield (3) during calorimetric measures by limiting the heat flux same. In fact, in operative conditions the dynamic shield acts as thermal flywheel and keeps constant the heat flux coming from the active shield (3).