Patents by Inventor Lucas Chase
Lucas Chase has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11973460Abstract: A mounting bracket assembly comprising may include an upper region with flat portions on either end that interface with a photovoltaic (PV) module and a lower portion in between the flat portions, and a central portion at least partially surrounding a hole shaped to accommodate a torsion beam. The mounting bracket assembly may also include side portions extending from the ends of the upper region to below the hole shaped to accommodate the torsion beam, and a first outer lining along a periphery of the mounting bracket assembly. The mounting bracket assembly may also include a second outer lining along the hole shaped to accommodate the torsion beam, and multiple ribs extending between the first outer lining and the second outer lining.Type: GrantFiled: May 8, 2021Date of Patent: April 30, 2024Assignee: ARRAY TECHNOLOGIES, INC.Inventors: Nathan Schuknecht, Lucas Creasy, Jason Addink, Andrew Chase
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Publication number: 20240108501Abstract: Provided for herein is a method of cell transplantation using an injection attachment having a hub containing a plurality of cells and a cannula extending from a distal end of the hub. The method includes orienting the injection attachment such that the cannula points downwardly until the plurality of cells settle together proximate the distal end, inserting the cannula into a tissue of a subject, and injecting the volume of cells into the tissue of the subject using the injection attachment.Type: ApplicationFiled: September 30, 2023Publication date: April 4, 2024Applicant: FUJIFILM Cellular Dynamics, Inc.Inventors: Tianran LIU, Randy LEARISH, Cayla THOMPSON, Matthew STERNFELD, Michael PHILLIPS, Virginia MATTIS, Lucas CHASE, Erik BROWN
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Publication number: 20230212509Abstract: Provided herein are methods of producing a distinct bilayer culture of retinal epithelial cells (RPE) with photoreceptor cells and/or photoreceptor precursor cells (PR/PRP). Further provided herein is a therapy comprising transplantation of the RPE and PR/PRP bilayer as well as methods for testing candidate drugs using the bilayer.Type: ApplicationFiled: May 28, 2021Publication date: July 6, 2023Applicants: FUJIFILM Cellular Dynamics, Inc., The United States of America, as represented by the Secretary, Department of Health and Human ServicInventors: Andrew DIAS, Erich BERNDT, Lucas CHASE, Juan AMARAL, Arvydas MAMINISHKIS, Kapil BHARTI
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Publication number: 20230201267Abstract: Provided herein is a dual cell aggregate culture of retinal epithelial cells and photoreceptors for use as a research tool, such as the screening of compounds or model for study of retinal diseases, as well as a therapeutic for treating ocular diseases.Type: ApplicationFiled: May 28, 2021Publication date: June 29, 2023Applicant: FUJIFILM Cellular Dynamics, Inc.Inventors: Andrew DIAS, Erich BERNDT, Lucas CHASE
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Publication number: 20220033770Abstract: Provided herein are methods of enriching a retinal pigment epithelium (RPE) cell population derived from stem cells. Such a method may comprise removing contaminating cells through the depletion of CD24 positive cells, CD56 positive cells, and/or CD90 positive cells from a starting population of RPE cells.Type: ApplicationFiled: October 4, 2021Publication date: February 3, 2022Applicant: FUJIFILM Cellular Dynamics, Inc.Inventors: Nathan MEYER, Lucas CHASE, Casey STANKEWICZ
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Patent number: 11162070Abstract: Provided herein are methods of enriching a retinal pigment epithelium (RPE) cell population derived from stem cells. Such a method may comprise removing contaminating cells through the depletion of CD24 positive cells, CD56 positive cells, and/or CD90 positive cells from a starting population of RPE cells.Type: GrantFiled: September 7, 2016Date of Patent: November 2, 2021Assignee: FUJIFILM Cellular Dynamics, Inc.Inventors: Nathan Meyer, Lucas Chase, Casey Stankewicz
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Publication number: 20210238546Abstract: Provided herein are methods of producing a photoreceptor precursor (PRP) cell population derived from stem cells. Further provided herein are methods of using the PRP cell populations, such as for therapeutics.Type: ApplicationFiled: April 22, 2019Publication date: August 5, 2021Applicant: FUJIFILM Cellular Dynamics, Inc.Inventors: Lucas CHASE, Kyle WALLACE, Benjamin MELINE, Andrew DIAS, Brandon SHELLEY, Marisa FENN, Debjani PHILLIPS, Matthew STERNFELD, Nathan MEYER
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Publication number: 20210139847Abstract: Provided herein are methods of producing an RPE cell population from a starting cell suspension, such as a single cell suspension, of pluripotent stem cells (PSCs). Such a method may comprise culturing the starting single cell suspension of PSCs in differentiation media to produce human RPE cells.Type: ApplicationFiled: July 16, 2020Publication date: May 13, 2021Applicants: The United States of America,as represented by the Secretary,Department of Health and Human Services, FUJIFILM Cellular Dynamics, Inc.Inventors: Kapil Bharti, Lucas Chase, Feng Xuezhu, Balendu Shekhar Jha
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Patent number: 10828335Abstract: Methods are provided for efficient production of midbrain dopaminergic (DA) neurons. In some aspects, methods involve differentiation and selection of DA neurons for a transgenic pluripotent cell population (e.g., cells comprising a selectable marker gene). Cell populations produced by the instant methods and methods of their use are likewise provided.Type: GrantFiled: June 6, 2017Date of Patent: November 10, 2020Assignee: FUJIFILM Cellular Dynamics, Inc.Inventors: Matt George, Carrie Chavez, Chris McMahon, Wen Bo Wang, Lucas Chase, Brad Swanson
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Publication number: 20190169569Abstract: Provided herein are methods of producing an RPE cell population from a starting cell suspension, such as a single cell suspension, of pluripotent stem cells (PSCs). Such a method may comprise culturing the starting single cell suspension of PSCs in differentiation media to produce human RPE cells.Type: ApplicationFiled: September 7, 2016Publication date: June 6, 2019Applicants: The United States of America, as represented by the Secretary, Department of Health and Human Serv, Cellular Dynamics International, Inc.Inventors: Kapil Bharti, Lucas Chase, Feng Xuezhu, Balendu Shekhar Jha
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Publication number: 20180021383Abstract: Methods are provided for efficient production of midbrain dopaminergic (DA) neurons. In some aspects, methods involve differentiation and selection of DA neurons for a transgenic pluripotent cell population (e.g., cells comprising a selectable marker gene). Cell populations produced by the instant methods and methods of their use are likewise provided.Type: ApplicationFiled: June 6, 2017Publication date: January 25, 2018Applicant: Cellular Dynamics International, Inc.Inventors: Matt GEORGE, Carrie CHAVEZ, Chris McMAHON, Wen Bo WANG, Lucas CHASE, Brad SWANSON
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Patent number: 9694036Abstract: Methods are provided for efficient production of midbrain dopaminergic (DA) neurons. In some aspects, methods involve differentiation and selection of DA neurons for a transgenic pluripotent cell population (e.g., cells comprising a selectable marker gene). Cell populations produced by the instant methods and methods of their use are likewise provided.Type: GrantFiled: March 20, 2015Date of Patent: July 4, 2017Assignee: Cellular Dynamics International, Inc.Inventors: Matt George, Carrie Chavez, Chris McMahon, Wen Bo Wang, Lucas Chase, Brad Swanson
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Publication number: 20170067017Abstract: Provided herein are methods of enriching a retinal pigment epithelium (RPE) cell population derived from stem cells. Such a method may comprise removing contaminating cells through the depletion of CD24 positive cells, CD56 positive cells, and/or CD90 positive cells from a starting population of RPE cells.Type: ApplicationFiled: September 7, 2016Publication date: March 9, 2017Applicant: Cellular Dynamics International, Inc.Inventors: Nathan MEYER, Lucas CHASE, Casey STANKEWICZ
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Publication number: 20160010113Abstract: The disclosure relates generally to genetic manipulation of stem and primary cells and to reprogramming of somatic cells, more specifically, human cells. In particular, compositions and methods are disclosed for the generation and maintenance of such engineered cells.Type: ApplicationFiled: July 16, 2015Publication date: January 14, 2016Inventors: Uma LAKSHMIPATHY, Bhaskar Thyagarajan, Jonathan Chesnut, Vasiliki Anest, Robert Bennett, Pauline Lieu, George Hanson, David Thompson, Lucas Chase, Gary Shipley, Elizabeth Wilson
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Publication number: 20150265652Abstract: Methods are provided for efficient production of midbrain dopaminergic (DA) neurons. In some aspects, methods involve differentiation and selection of DA neurons for a transgenic pluripotent cell population (e.g., cells comprising a selectable marker gene). Cell populations produced by the instant methods and methods of their use are likewise provided.Type: ApplicationFiled: March 20, 2015Publication date: September 24, 2015Inventors: Matt GEORGE, Carrie CHAVEZ, Chris MCMAHON, Wen Bo WANG, Lucas CHASE, Brad SWANSON
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Patent number: 9005964Abstract: The present invention relates to endodermal progenitor cells and methods of isolation, culture, differentiation and use thereof.Type: GrantFiled: November 26, 2007Date of Patent: April 14, 2015Assignee: Regents of the University of MinnesotaInventors: Catherine Verfaillie, Lucas Chase
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Publication number: 20130164269Abstract: The present invention relates to growing stem cells, for e.g., MSCs, in large-scale under GMP-compliance, using media and reagents that satisfy GMP requirements, while maintaining stemness, for effective downstream therapeutic use, which include but are not limited to, stem cell therapy, production of products, such as beneficial factors, recombinant proteins, etc. obtained from such stem cells.Type: ApplicationFiled: September 2, 2011Publication date: June 27, 2013Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Andrew Mark Campbell, Lucas Chase, Mohanachari Vemuri
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Publication number: 20130040304Abstract: The disclosure relates generally to genetic manipulation of stem and primary cells and to reprogramming of somatic cells, more specifically, human cells. In particular, compositions and methods are disclosed for the generation and maintenance of such engineered cells.Type: ApplicationFiled: August 9, 2012Publication date: February 14, 2013Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: UMA LAKSHMIPATHY, BHASKAR THYAGARAJAN, JONATHAN CHESNUT, VASILIKI ANEST, ROBERT BENNETT, PAULINE LIEU, GEORGE HANSON, DAVID THOMPSON, LUCAS CHASE, GARY SHIPLEY, ELIZABETH WILSON
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Publication number: 20110263001Abstract: The disclosure relates generally to genetic manipulation of stem and primary cells and to reprogramming of somatic cells, more specifically, human cells. In particular, compositions and methods are disclosed for the generation and maintenance of such engineered cells.Type: ApplicationFiled: November 13, 2009Publication date: October 27, 2011Applicant: Life Technologies CorporationInventors: Uma Lakshmipathy, Bhaskar Thyagarajan, Jonathan Chesnut, Vasiliki Anest, Robert Bennett, Pauline Lieu, George Hanson, David Thompson, Lucas Chase, Gary Shipley, Elizabeth Wilson
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Publication number: 20100150876Abstract: The present invention relates to endodermal progenitor cells and methods of isolation, culture, differentiation and use thereof.Type: ApplicationFiled: November 26, 2007Publication date: June 17, 2010Applicant: Regents of the Univeristy of MinnesotaInventors: Catherine Verfaillie, Lucas Chase