Patents by Inventor Lucian Mihailescu
Lucian Mihailescu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240148346Abstract: Improved imaging devices and methods. A portable SPECT imaging device may co-register with imaging modalities such as ultrasound. Gamma camera panels including gamma camera sensors may be connected to a mechanical arm. A coded aperture mask may be placed in front of a gamma-ray photon sensor and used to construct a high-resolution three-dimensional map of radioisotope distributions inside a patient, which can be generated by scanning the patient from a reduced range of directions around the patient and with radiation sensors placed in close proximity to this patient. Increased imaging sensitivity and resolution is provided. The SPECT imaging device can be used to guide medical interventions, such as biopsies and ablation therapies, and can also be used to guide surgeries.Type: ApplicationFiled: December 15, 2023Publication date: May 9, 2024Inventors: Michael Quinlan, Lucian Mihailescu, Andrei Claudiu Cosma
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Patent number: 11883214Abstract: Improved imaging devices and methods. A portable SPECT imaging device may co-register with imaging modalities such as ultrasound. Gamma camera panels including gamma camera sensors may be connected to a mechanical arm. A coded aperture mask may be placed in front of a gamma-ray photon sensor and used to construct a high-resolution three-dimensional map of radioisotope distributions inside a patient, which can be generated by scanning the patient from a reduced range of directions around the patient and with radiation sensors placed in close proximity to this patient. Increased imaging sensitivity and resolution is provided. The SPECT imaging device can be used to guide medical interventions, such as biopsies and ablation therapies, and can also be used to guide surgeries.Type: GrantFiled: July 28, 2022Date of Patent: January 30, 2024Assignee: Ziteo, Inc.Inventors: Michael Quinlan, Lucian Mihailescu, Andrei Claudiu Cosma
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Publication number: 20230389801Abstract: A shared-housing ultrasound transducer and machine-vision camera system is disclosed for registering the transducer's x, y, z position in space and pitch, yaw, and roll orientation with respect to an object, such as a patient's body. The position and orientation are correlated with transducer scan data, and scans of the same region of the object are compared in order to reduce ultrasound artifacts and speckles. The system can be extended to interoperative gamma probes or other non-contact sensor probes and medical instruments. Methods are disclosed for computer or remote guiding of a sensor probe or instrument with respect to saved positions and orientations of the sensor probe.Type: ApplicationFiled: April 28, 2023Publication date: December 7, 2023Inventors: Lucian Mihailescu, Victor Arie Negut
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Patent number: 11678804Abstract: A shared-housing ultrasound transducer and machine-vision camera system is disclosed for registering the transducer's x, y, z position in space and pitch, yaw, and roll orientation with respect to an object, such as a patient's body. The position and orientation are correlated with transducer scan data, and scans of the same region of the object are compared in order to reduce ultrasound artifacts and speckles. The system can be extended to interoperative gamma probes or other non-contact sensor probes and medical instruments. Methods are disclosed for computer or remote guiding of a sensor probe or instrument with respect to saved positions and orientations of the sensor probe.Type: GrantFiled: July 16, 2019Date of Patent: June 20, 2023Assignee: Ziteo, Inc.Inventors: Lucian Mihailescu, Victor Arie Negut
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Publication number: 20230030008Abstract: Improved imaging devices and methods. A portable SPECT imaging device may co-register with imaging modalities such as ultrasound. Gamma camera panels including gamma camera sensors may be connected to a mechanical arm. A coded aperture mask may be placed in front of a gamma-ray photon sensor and used to construct a high-resolution three-dimensional map of radioisotope distributions inside a patient, which can be generated by scanning the patient from a reduced range of directions around the patient and with radiation sensors placed in close proximity to this patient. Increased imaging sensitivity and resolution is provided. The SPECT imaging device can be used to guide medical interventions, such as biopsies and ablation therapies, and can also be used to guide surgeries.Type: ApplicationFiled: July 28, 2022Publication date: February 2, 2023Inventors: Michael Quinlan, Lucian Mihailescu, Andrei Claudiu Cosma
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Publication number: 20230028501Abstract: The present disclosure relates, in part, to a scanning sufficiency apparatus that computes whether a handheld scanning device has scanned a volume for a sufficiently long time for there to be detections and then indicate to the user that the time is sufficient in 3-D rendered voxels. Also described is a hand held medical navigation apparatus with system and methods to map targets inside a patient's body.Type: ApplicationFiled: September 8, 2022Publication date: January 26, 2023Inventors: Lucian Mihailescu, Michael J. Quinlan, Victor Arie Negut
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Patent number: 11464503Abstract: The present disclosure relates, in part, to a scanning sufficiency apparatus that computes whether a handheld scanning device has scanned a volume for a sufficiently long time for there to be detections and then indicate to the user that the time is sufficient in 3-D rendered voxels. Also described is a hand held medical navigation apparatus with system and methods to map targets inside a patient's body.Type: GrantFiled: February 25, 2020Date of Patent: October 11, 2022Assignee: ZITEO, INC.Inventors: Lucian Mihailescu, Michael J. Quinlan, Victor Arie Negut
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Patent number: 11439358Abstract: Improved imaging devices and methods. A portable SPECT imaging device may co-register with imaging modalities such as ultrasound. Gamma camera panels including gamma camera sensors may be connected to a mechanical arm. A coded aperture mask may be placed in front of a gamma-ray photon sensor and used to construct a high-resolution three-dimensional map of radioisotope distributions inside a patient, which can be generated by scanning the patient from a reduced range of directions around the patient and with radiation sensors placed in close proximity to this patient. Increased imaging sensitivity and resolution is provided. The SPECT imaging device can be used to guide medical interventions, such as biopsies and ablation therapies, and can also be used to guide surgeries.Type: GrantFiled: April 9, 2020Date of Patent: September 13, 2022Assignee: Ziteo, Inc.Inventors: Michael Quinlan, Lucian Mihailescu, Andrei Claudiu Cosma
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Publication number: 20220087624Abstract: Improved imaging devices and methods. A portable SPECT imaging device may co-register with imaging modalities such as ultrasound. Gamma camera panels including gamma camera sensors may be connected to a mechanical arm. A coded aperture mask may be placed in front of a gamma-ray photon sensor and used to construct a high-resolution three-dimensional map of radioisotope distributions inside a patient, which can be generated by scanning the patient from a reduced range of directions around the patient and with radiation sensors placed in close proximity to this patient. Increased imaging sensitivity and resolution is provided. The SPECT imaging device can be used to guide medical interventions, such as biopsies and ablation therapies, and can also be used to guide surgeries.Type: ApplicationFiled: April 9, 2020Publication date: March 24, 2022Inventors: Michael Quinlan, Lucian Mihailescu, Andrei Claudiu Cosma
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Publication number: 20200187925Abstract: The present disclosure relates, in part, to a scanning sufficiency apparatus that computes whether a handheld scanning device has scanned a volume for a sufficiently long time for there to be detections and then indicate to the user that the time is sufficient in 3-D rendered voxels. Also described is a hand held medical navigation apparatus with system and methods to map targets inside a patient's body.Type: ApplicationFiled: February 25, 2020Publication date: June 18, 2020Inventors: Lucian Mihailescu, Michael J. Quinlan, Victor Arie Negut
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Patent number: 10617401Abstract: The present disclosure relates, in part, to a scanning sufficiency apparatus that computes whether a handheld scanning device has scanned a volume for a sufficiently long time for there to be detections and then indicate to the user that the time is sufficient in 3-D rendered voxels. Also described is a hand held medical navigation apparatus with system and methods to map targets inside a patient's body.Type: GrantFiled: November 12, 2015Date of Patent: April 14, 2020Assignee: ZITEO, INC.Inventors: Lucian Mihailescu, Michael J. Quinlan, Victor Arie Negut
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Publication number: 20190336004Abstract: A shared-housing ultrasound transducer and machine-vision camera system is disclosed for registering the transducer's x, y, z position in space and pitch, yaw, and roll orientation with respect to an object, such as a patient's body. The position and orientation are correlated with transducer scan data, and scans of the same region of the object are compared in order to reduce ultrasound artifacts and speckles. The system can be extended to interoperative gamma probes or other non-contact sensor probes and medical instruments. Methods are disclosed for computer or remote guiding of a sensor probe or instrument with respect to saved positions and orientations of the sensor probe.Type: ApplicationFiled: July 16, 2019Publication date: November 7, 2019Applicant: Ziteo, Inc.Inventors: Lucian Mihailescu, Victor Arie Negut
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Patent number: 10426350Abstract: A shared-housing ultrasound transducer and machine-vision camera system is disclosed for registering the transducer's x, y, z position in space and pitch, yaw, and roll orientation with respect to an object, such as a patient's body. The position and orientation are correlated with transducer scan data, and scans of the same region of the object are compared in order to reduce ultrasound artifacts and speckles. The system can be extended to interoperative gamma probes or other non-contact sensor probes and medical instruments. Methods are disclosed for computer or remote guiding of a sensor probe or instrument with respect to saved positions and orientations of the sensor probe.Type: GrantFiled: April 29, 2016Date of Patent: October 1, 2019Assignee: ZITEO, INC.Inventors: Lucian Mihailescu, Victor Arie Negut
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Patent number: 9849307Abstract: This disclosure provides systems, methods, and apparatus related to ion beam therapy. In one aspect, a system includes a position sensitive detector and a collimator. The position sensitive detector configured to detect gamma rays generated by an ion beam interacting with a target. The collimator is positioned between the target and the position sensitive detector. The collimator includes a plurality of knife-edge slits, with a first knife-edge slit intersecting with a second knife-edge slit.Type: GrantFiled: October 19, 2015Date of Patent: December 26, 2017Assignee: The Regents of the University of CaliforniaInventor: Lucian Mihailescu
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Patent number: 9561019Abstract: A shared-housing ultrasound transducer and machine-vision camera system is disclosed for registering the transducer's x, y, z position in space and pitch, yaw, and roll orientation with respect to an object, such as a patient's body. The position and orientation are correlated with transducer scan data, and scans of the same region of the object are compared in order to reduce ultrasound artifacts and speckles. The system can be extended to interoperative gamma probes or other non-contact sensor probes and medical instruments. Methods are disclosed for computer or remote guiding of a sensor probe or instrument with respect to saved positions and orientations of the sensor probe.Type: GrantFiled: March 7, 2013Date of Patent: February 7, 2017Assignee: ZITEO, INC.Inventors: Lucian Mihailescu, Victor Arie Negut
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Publication number: 20160242744Abstract: A shared-housing ultrasound transducer and machine-vision camera system is disclosed for registering the transducer's x, y, z position in space and pitch, yaw, and roll orientation with respect to an object, such as a patient's body. The position and orientation are correlated with transducer scan data, and scans of the same region of the object are compared in order to reduce ultrasound artifacts and speckles. The system can be extended to interoperative gamma probes or other non-contact sensor probes and medical instruments. Methods are disclosed for computer or remote guiding of a sensor probe or instrument with respect to saved positions and orientations of the sensor probe.Type: ApplicationFiled: April 29, 2016Publication date: August 25, 2016Applicant: Ziteo, Inc.Inventors: Lucian Mihailescu, Victor Arie Negut
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Publication number: 20160135762Abstract: The present disclosure relates, in part, to a scanning sufficiency apparatus that computes whether a handheld scanning device has scanned a volume for a sufficiently long time for there to be detections and then indicate to the user that the time is sufficient in 3-D rendered voxels. Also described is a hand held medical navigation apparatus with system and methods to map targets inside a patient's body.Type: ApplicationFiled: November 12, 2015Publication date: May 19, 2016Applicant: Ziteo, Inc.Inventors: Lucian Mihailescu, Michael J. Quinlan, Victor Arie Negut
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Publication number: 20160114189Abstract: This disclosure provides systems, methods, and apparatus related to ion beam therapy. In one aspect, a system includes a position sensitive detector and a collimator. The position sensitive detector configured to detect gamma rays generated by an ion beam interacting with a target. The collimator is positioned between the target and the position sensitive detector. The collimator includes a plurality of knife-edge slits, with a first knife-edge slit intersecting with a second knife-edge slit.Type: ApplicationFiled: October 19, 2015Publication date: April 28, 2016Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventor: Lucian Mihailescu
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Publication number: 20130237811Abstract: A shared-housing ultrasound transducer and machine-vision camera system is disclosed for registering the transducer's x, y, z position in space and pitch, yaw, and roll orientation with respect to an object, such as a patient's body. The position and orientation are correlated with transducer scan data, and scans of the same region of the object are compared in order to reduce ultrasound artifacts and speckles. The system can be extended to interoperative gamma probes or other non-contact sensor probes and medical instruments. Methods are disclosed for computer or remote guiding of a sensor probe or instrument with respect to saved positions and orientations of the sensor probe.Type: ApplicationFiled: March 7, 2013Publication date: September 12, 2013Applicant: Speir Technologies Inc.Inventors: Lucian Mihailescu, Victor Arie Negut
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Patent number: 8519343Abstract: Apparatus for detecting and locating a source of gamma rays of energies ranging from 10-20 keV to several MeV's includes plural gamma ray detectors arranged in a generally closed extended array so as to provide Compton scattering imaging and coded aperture imaging simultaneously. First detectors are arranged in a spaced manner about a surface defining the closed extended array which may be in the form a circle, a sphere, a square, a pentagon or higher order polygon. Some of the gamma rays are absorbed by the first detectors closest to the gamma source in Compton scattering, while the photons that go unabsorbed by passing through gaps disposed between adjacent first detectors are incident upon second detectors disposed on the side farthest from the gamma ray source, where the first spaced detectors form a coded aperture array for two or three dimensional gamma ray source detection.Type: GrantFiled: April 25, 2011Date of Patent: August 27, 2013Assignee: U.S. Department of EnergyInventors: Lucian Mihailescu, Kai M. Vetter