Patents by Inventor Luciano De Petrocellis
Luciano De Petrocellis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180042975Abstract: This invention relates to the use of phytocannabinoids, either in an isolated form or in the form of a botanical drug substance (BDS) in the treatment of cancer. Preferably the cancer to be treated is cancer of the prostate, cancer of the breast or cancer of the colon.Type: ApplicationFiled: June 12, 2017Publication date: February 15, 2018Applicants: GW Pharma Limited, Otsuka Pharmaceutical Co., LimitedInventors: Daniela Parolaro, Paola Massi, Angelo Antonio Izzo, Francesca Borrelli, Gabriella Aviello, Vincenzo Di Marzo, Luciano De Petrocellis, Aniello Schiano Moriello, Alessia Ligresti, Ruth Alexandra Ross, Lesley Ann Ford, Sharon Anavi-Goffer, Manuel Guzman, Guillermo Velasco, Mar Lorente, Sofia Torres, Tetsuro Kikuchi, Geoffrey Guy, Colin Stott, Stephen Wright, Alan Sutton, David Potter, Etienne De Meijer
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Patent number: 9675654Abstract: This invention relates to the use of phytocannabinoids, either in an isolated form or in the form of a botanical drug substance (BDS) in the treatment of cancer. Preferably the cancer to be treated is cancer of the prostate, cancer of the breast or cancer of the colon.Type: GrantFiled: April 24, 2014Date of Patent: June 13, 2017Assignees: GW Pharma Limited, Otsuka Pharmaceutical Co., LimitedInventors: Daniela Parolaro, Paola Massi, Angelo Antonio Izzo, Francesca Borrelli, Gabriella Aviello, Vincenzo Di Marzo, Luciano De Petrocellis, Aniello Schiano Moriello, Alessia Ligresti, Ruth Alexandra Ross, Lesley Ann Ford, Sharon Anavi-Goffer, Manuel Guzman, Guillermo Velasco, Mar Lorente, Sofia Torres, Tetsuro Kikuchi, Geoffrey Guy, Colin Stott, Stephen Wright, Alan Sutton, David Potter, Etienne De Meijer
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Publication number: 20150086653Abstract: This invention relates to the use of phytocannabinoids, either in an isolated form or in the form of a botanical drug substance (BDS) in the treatment of cancer. Preferably the cancer to be treated is cancer of the prostate, cancer of the breast or cancer of the colon.Type: ApplicationFiled: April 24, 2014Publication date: March 26, 2015Applicants: GW Pharma Limited, Otsuka Pharmaceutical Co., LimitedInventors: Daniela Parolaro, Paola Massi, Angelo Antonio Izzo, Francesca Borelli, Gabriella Aviello, Vincenzo Di Marzo, Luciano De Petrocellis, Aniello Schiano Moriello, Alessia Ligresti, Ruth Alexandra Ross, Lesley Ann Ford, Sharon Anavi-Goffer, Manuel Guzman, Guillermo Velasco, Mar Lorente, Sofia Torres, Tetsuro Kikuchi, Geoffrey Guy, Colin Stott, Stephen Wright, Alan Sutton, David Potter, Etienne De Meijer
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Patent number: 8790719Abstract: This invention relates to the use of phytocannabinoids, either in an isolated form or in the form of a botanical drug substance (BDS) in the treatment of cancer. Preferably the cancer to be treated is cancer of the prostate, cancer of the breast or cancer of the colon.Type: GrantFiled: March 11, 2011Date of Patent: July 29, 2014Assignees: GW Pharma Limited, Otsuka Pharmaceutical Co., LimitedInventors: Daniela Parolaro, Paola Massi, Angelo Antonio Izzo, Francesca Borelli, Gabriella Aviello, Vincenzo Di Marzo, Luciano De Petrocellis, Aniello Schiano Moriello, Alessia Ligresti, Ruth Alexandra Ross, Lesley Ann Ford, Sharon Anavi-Goffer, Manuel Guzman, Guillermo Velasco, Mar Lorente, Sofia Torres, Tetsuro Kikuchi, Geoffrey Guy, Colin Stott, Stephen Wright, Alan Sutton, David Potter, Etienne De Meijer
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Publication number: 20140066399Abstract: The present invention relates to topical preparations containing N-palmitoyl-vanillamide having hyperalgesic activity. In particular, the invention relates to N-palmitoyl-vanillamide for use in the treatment of pathologies selected from: post-herpetic neuralgia, neuralgia of trigeminus, occipital neuralgia, dental neuralgia, glottopharyngeal neuralgia, uremic neuralgia, diabetic neuralgia, headache of different origin, neuropathic itch, neurogenic itch, uremic itch, vulvodinia, vulvar vestibulitis, ano-rectal pain and itch, balano-preputial pain and itch, painful urogenital disorders of dogs and cats, psoriasis-associated pruritus and pain, itching skin diseases (e.g. atopic dermatitis) in the human and veterinary field, muscular pain, pain of the tendon, osteoarthritis associated pain in humans, dogs and cats; painful eye diseases in the human and veterinary field, inflammatory pathologies of the oral cavity in the human and veterinary field.Type: ApplicationFiled: August 28, 2013Publication date: March 6, 2014Applicant: EPITECH GROUP S.R.L.Inventors: Francesco Della Valle, Luciano De Petrocellis, Sabatino Maione, Vincenzo Di Marzo, Maria Federica Della Valle
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Patent number: 8546352Abstract: The present invention relates to topical preparations containing N-palmitoyl-vanillamide having hyperalgesic activity. In particular, the invention relates to N-palmitoyl-vanillamide for use in the treatment of pathologies selected from: post-herpetic neuralgia, neuralgia of trigeminus, occipital neuralgia, dental neuralgia, glottopharyngeal neuralgia, uremic neuralgia, diabetic neuralgia, headache of different origin, neuropathic itch, neurogenic itch, uremic itch, vulvodinia, vulvar vestibulitis, ano-rectal pain and itch, balano-preputial pain and itch, painful urogenital disorders of dogs and cats, psoriasis-associated pruritus and pain, itching skin diseases (e.g. atopic dermatitis) in the human and veterinary field, muscular pain, pain of the tendon, osteoarthritis associated pain in humans, dogs and cats; painful eye diseases in the human and veterinary field, inflammatory pathologies of the oral cavity in the human and veterinary field.Type: GrantFiled: November 8, 2011Date of Patent: October 1, 2013Assignee: Epitech Group S.r.l.Inventors: Francesco Della Valle, Luciano De Petrocellis, Sabatino Maione, Vincenzo Di Marzo, Maria Federica Della Valle
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Publication number: 20130059018Abstract: This invention relates to the use of phytocannabinoids, either in an isolated form or in the form of a botanical drug substance (BDS) in the treatment of cancer. Preferably the cancer to be treated is cancer of the prostate, cancer of the breast or cancer of the colon.Type: ApplicationFiled: March 11, 2011Publication date: March 7, 2013Applicants: OTSUKA PHARMACEUTICAL CO., LIMITED, GW PHARMA LIMITEDInventors: Daniela Parolaro, Paola Massi, Angelo Antonio Izzo, Francesca Borelli, Gabriella Aviello, Vincenzo Di Marzo, Luciano De Petrocellis, Aniello Schiano Moriello, Alessia Ligresti, Ruth Alexandra Ross, Lesley Ann Ford, Sharon Anavi-Goffer, Manuel Guzman, Guillermo Velasco, Mar Lorente, Sofia Torres, Tetsuro Kikuchi, Geoffrey Guy, Colin Stott, Stephen Wright, Alan Sutton, David Potter, Etienne De Meijer
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Publication number: 20120115808Abstract: The present invention relates to topical preparations containing N-palmitoyl-vanillamide having hyperalgesic activity. In particular, the invention relates to N-palmitoyl-vanillamide for use in the treatment of pathologies selected from: post-herpetic neuralgia, neuralgia of trigeminus, occipital neuralgia, dental neuralgia, glottopharyngeal neuralgia, uremic neuralgia, diabetic neuralgia, headache of different origin, neuropathic itch, neurogenic itch, uremic itch, vulvodinia, vulvar vestibulitis, ano-rectal pain and itch, balano-preputial pain and itch, painful urogenital disorders of dogs and cats, psoriasis-associated pruritus and pain, itching skin diseases (e.g. atopic dermatitis) in the human and veterinary field, muscular pain, pain of the tendon, osteoarthritis associated pain in humans, dogs and cats; painful eye diseases in the human and veterinary field, inflammatory pathologies of the oral cavity in the human and veterinary field.Type: ApplicationFiled: November 8, 2011Publication date: May 10, 2012Inventors: Francesco DELLA VALLE, Luciano De Petrocellis, Sabatino Maione, Vincenzo Di Marzo, Maria Federica Della Valle
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Patent number: 7902251Abstract: The present invention provides pharmaceutical compositions useful in a method for treating neuropathic pain, said method comprising administration of a pain-ameliorating effective amount of the compound according to formula I wherein R is an alk(en)yl group, R1 is an alkylen(yl) group, n is 0 or 1 and Ar is a carbocyclic aryl group.Type: GrantFiled: October 13, 2006Date of Patent: March 8, 2011Assignee: Allergan, Inc.Inventors: Vincenzo Di Marzo, Luciano De Petrocellis, Sabatino Malone, Vito De Novellis
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Publication number: 20100249223Abstract: The present invention relates to the use of cannabinoid-containing plant extracts in the prevention or treatment of diseases or conditions that are alleviated by blockade of one or more types of TRP channel. Preferably the subset of TRP channel that is blockaded is the TRPA channel. More preferably the TRPA channel is the TRPA1 channel. Preferably the diseases or conditions to be prevented or treated include: neuropathic pain, inflammation or vasoconstriction. Alternatively the TRP channel that is blockaded is the TRPM channel. More preferably the TRPM channel is the TRPM8 channel. Preferably the diseases or conditions to be prevented or treated are cancer. More preferably the cancers to be treated include: cancer of the prostate, cancer of the breast, cancer of the colon, cancer of the lung or cancer of the skin. Alternatively the TRP channel that is blockaded is the TRPV channel. More preferably the TRPV channel is the TRPV1 channel.Type: ApplicationFiled: April 17, 2008Publication date: September 30, 2010Applicant: GW Pharma LimitedInventors: Vincenzo Di Marzo, Luciano De Petrocellis, Aniello Schiano Moriello
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Publication number: 20070259945Abstract: The present invention provides pharmaceutical compositions useful in a method for treating neuropathic pain, said method comprising administration of a pain-ameliorating effective amount of the compound according to formula I wherein X may be Y may be wherein R is H or (CH2)mH, alternatively the bond between X and Y may be a double or triple bond, e.g. X?Y or X?Y; wherein n is an integer of from 1 to 10, m is an integer of from 1 to 4 and the total carbon atoms in the alkenyl amide chain is from about 11 to about 20 as an active ingredient together with one or more pharmaceutically-acceptable additives, excipients or diluents.Type: ApplicationFiled: October 13, 2006Publication date: November 8, 2007Applicant: ALLERGAN, INC.Inventors: Luciano De Petrocellis, Sabatino Malone, Vito De Novellis, Vincenzo Di Marzo
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Patent number: 7244767Abstract: The present invention relates to the use of N-acylvanillinamide derivatives capable of activating the peripheral receptor CB1 of cannabinoids. In particular, the present invention relates to the use of compounds of general formula (I) in which the meanings of R, R1, R3 and Y are as defined in the description, for the preparation of a medicinal product which is capable of activating the peripheral receptor CB1 of cannabinoids.Type: GrantFiled: September 27, 2004Date of Patent: July 17, 2007Assignees: Innovet Italia S.R.L., Consiglio Nazionale Delle RichercheInventors: Tiziana Bisogno, Francesco Della Valle, Luciano De Petrocellis, Vincenzo Di Marzo, Gabriele Marcolongo, Dominique Melck
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Publication number: 20070129424Abstract: The present invention provides pharmaceutical compositions useful in a method for treating neuropathic pain, said method comprising administration of a pain-ameliorating effective amount of the compound according to formula I wherein R is an alk(en)yl group, R1 is an alkylen(yl) group, n is 0 or 1 and Ar is a carbocyclic aryl group.Type: ApplicationFiled: February 6, 2007Publication date: June 7, 2007Inventors: Vicenzo Di Marzo, Luciano De Petrocellis, Sabatino Malone, Vito De Novellis, David Woodward
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Publication number: 20070129423Abstract: The present invention provides pharmaceutical compositions useful in a method for treating neuropathic pain, said method comprising administration of a pain-ameliorating effective amount of the compound according to formula I wherein R is an alk(en)yl group, R1 is an alkylen(yl) group, n is 0 or 1 and Ar is a carbocyclic aryl group; wherein X is Y is O, S, or NR wherein R is H or (CH2)mH and m is an integer of from 1 to 5 or the bond between X and Y may be a double or triple bond, e.g. as in X?Y or X?Y.Type: ApplicationFiled: February 6, 2007Publication date: June 7, 2007Inventors: Vincenzo Di Marzo, Luciano De Petrocellis, Sabatino Malone, Vito De Novellis, David Woodward
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Publication number: 20070105940Abstract: The present invention provides pharmaceutical compositions useful in a method for treating neuropathic pain, said method comprising administration of a pain-ameliorating effective amount of the compound according to formula I wherein n is an integer of from 1 to 10, m is an integer of from 1 to 4 and the total carbon atoms in the alkenyl amide chain is from about 11 to about 20 as an active ingredient together with one or more pharmaceutically-acceptable additives, excipients or diluents.Type: ApplicationFiled: October 13, 2006Publication date: May 10, 2007Applicant: ALLERGAN, INC.Inventors: Vincenzo Di Marzo, Luciano De Petrocellis, Sabatino Malone, Vito De Novellis
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Publication number: 20070088073Abstract: The present invention provides pharmaceutical compositions useful in a method for treating neuropathic pain, said method comprising administration of a pain-ameliorating effective amount of the compound according to formula I wherein R is an alk(en)yl group, R1 is an alkylen(yl) group, n is 0 or 1 and Ar is a carbocyclic aryl group; wherein X is —CH2—, —CH—, or O, S, or NR wherein R is H or (CH2)mH and m is an integer of from 1 to 5 or the bond between X and Y may be a double or triple bond, e.g. as in X?Y or X?Y.Type: ApplicationFiled: October 13, 2006Publication date: April 19, 2007Applicant: ALLERGAN, INC.Inventors: Vincenzo Di Marzo, Luciano De Petrocellis, Sabatino Malone, Vito De Novellis
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Publication number: 20070088072Abstract: The present invention provides pharmaceutical compositions useful in a method for treating neuropathic pain, said method comprising administration of a pain-ameliorating effective amount of the compound according to formula I wherein R is an alk(en)yl group, R1 is an alkylen(yl) group, n is 0 or 1 and Ar is a carbocyclic aryl group.Type: ApplicationFiled: October 13, 2006Publication date: April 19, 2007Applicant: ALLERGAN, INC.Inventors: Vincenzo Di Marzo, Luciano De Petrocellis, Sabatino Malone, Vito De Novellis
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Publication number: 20050065216Abstract: The present invention relates to the use of N-acylvanillinamide derivatives capable of activating the peripheral receptor CB1 of cannabinoids. In particular, the present invention relates to the use of compounds of general formula (I) in which the meanings of R, R1, R3 and Y are as defined in the description, for the preparation of a medicinal product which is capable of activating the peripheral receptor CB1 of cannabinoids.Type: ApplicationFiled: September 27, 2004Publication date: March 24, 2005Applicants: Innovet Italia S.R.L., Consiglio Nazionale Delle RicercheInventors: Tiziana Bisogno, Francesco Della Valle, Luciano De Petrocellis, Vincenzo Di Marzo, Gabriele Marcolongo, Dominique Melck