Patents by Inventor Lucie Simonetti
Lucie Simonetti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9316653Abstract: The invention relates to the use of one or more complexed or noncomplexed, soluble peptide form(s) of Desmoglein I, as a marker for evaluating the effectiveness of active agents and/or of treatments, in particular anti-ageing active agents and/or treatments, with regard to an epidermis.Type: GrantFiled: January 14, 2010Date of Patent: April 19, 2016Assignee: L'OREALInventors: Mark Donovan, Lucie Simonetti, Dominique Bernard
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Patent number: 9295711Abstract: The present invention relates to the use, especially the cosmetic and/or therapeutic use, of the protein DJ-1, of polypeptides derived from this protein or of analogs thereof, of a nucleic acid sequence coding for such a polypeptide or of a modulator of the activity, stability or expression of such a polypeptide, especially for preventing and/or treating the signs of skin dryness. The invention also relates to the use of the protein DJ-1, of polypeptides derived from this protein or of analogs thereof or of a nucleic acid sequence coding for such a polypeptide, as a marker for evaluating the state of dryness of an epithelium.Type: GrantFiled: November 19, 2009Date of Patent: March 29, 2016Assignee: L'OREALInventors: Dominique Bernard, Lucie Simonetti, Isabelle Castiel
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Patent number: 8785397Abstract: The subject of the present invention is the use, in particular the cosmetic and/or therapeutic use, of the apolipoprotein D, of polypeptides derived from this protein or of analogues thereof, of a nucleic sequence encoding such a polypeptide or of an agent modulating the activity or of the expression of such a polypeptide, in particular for stimulating terminal epithelial differentiation. The invention also relates to the use of the protein apolipoprotein D, of polypeptides derived from this protein or of analogues thereof, or of a nucleic sequence encoding such a polypeptide as a marker for evaluating the state of the epidermis.Type: GrantFiled: June 20, 2008Date of Patent: July 22, 2014Assignee: L'OrealInventors: Dominique Bernard, Isabelle Castiel, Lucie Simonetti
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Patent number: 8609117Abstract: Cosmetic or pharmaceutical compositions comprising compounds of formula (I) and the corresponding salts thereof: wherein: R1 is a radical chosen from —COOR?, —CONR?R?, —CH2OR?, —COR?, —CH2R?, —SO2OR?, —PO3R?R? and —NHR?, wherein R? and R?, which may be identical or different, are defined herein; —R2 is chosen from saturated and unsaturated, linear, branched and cyclic hydrocarbon radicals comprising from 1 to 18 carbon atoms which are optionally substituted by from 1 to 5 identical or different entities chosen from —OR??, —OCOR??, —SR??, —SCOR??, NR??R??, —NHCOR??, halogen, —CN, —COOR?? and —COR??, wherein R?? and R??, which may be identical or different, are defined herein; as well as the use of these compounds, for example, to promote skin desquamation, to stimulate epidermal renewal and/or to combat the signs of skin ageing.Type: GrantFiled: March 22, 2010Date of Patent: December 17, 2013Assignee: L'Oreal S.A.Inventors: Christophe Boulle, Maria Dalko, Jean-Luc Leveque, Lucie Simonetti
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Patent number: 8603502Abstract: Cosmetic or pharmaceutical compositions comprising compounds of formula (I) and the corresponding salts thereof: wherein: R1 is a radical chosen from —COOR?, —CONR?R?, —CH2OR?, —COR?, —CH2R?, —SO2OR?, —PO3R?R? and —NHR?, wherein R? and R?, which may be identical or different, are defined herein; R2 is chosen from saturated and unsaturated, linear, branched and cyclic hydrocarbon radicals comprising from 1 to 18 carbon atoms which are optionally substituted by from 1 to 5 identical or different entities chosen from —OR??, —OCOR??, —SR??, —SCOR??, NR??R??, —NHCOR??, halogen, —CN, —COOR?? and —COR??, wherein R?? and R??, which may be identical or different, are defined herein, as well as the use of these compounds, for example, to promote skin desquamation, to stimulate epidermal renewal and/or to combat the signs of skin ageing.Type: GrantFiled: February 3, 2003Date of Patent: December 10, 2013Assignee: L'Oreal S.A.Inventors: Christophe Boulle, Maria Dalko, Jean-Luc Leveque, Lucie Simonetti
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Patent number: 8481594Abstract: Cosmetic or pharmaceutical compositions comprising compounds of formula (I) and the corresponding salts thereof: wherein: R1 is a radical chosen from —COOR?, —CONR?R?, —CH2OR?, —COR?, —CH2R?, —SO2OR?, —PO3R?R? and —NHR?, wherein R? and R?, which may be identical or different, are defined herein; R2 is chosen from saturated and unsaturated, linear, branched and cyclic hydrocarbon radicals comprising from 1 to 18 carbon atoms which are optionally substituted by from 1 to 5 identical or different entities chosen from —OR??, —OCOR??, —SCOR??, NR??R??, —NHCOR??, halogen, —CN, —COOR?? and —COR??, wherein R?? and R??, which may be identical or different, are defined herein; as well as the use of these compounds, for example, to promote skin desquamation, to stimulate epidermal renewal and/or to combat the signs of skin ageing.Type: GrantFiled: March 18, 2009Date of Patent: July 9, 2013Assignee: L'Oreal S. A.Inventors: Christophe Boulle, Maria Dalko, Jean-Luc Leveque, Lucie Simonetti
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Publication number: 20120114628Abstract: The present invention relates to the use, especially the cosmetic and/or therapeutic use, of the protein DJ-1, of polypeptides derived from this protein or of analogues thereof, of a nucleic acid sequence coding for such a polypeptide or of a modulator of the activity, stability or expression of such a polypeptide, especially for preventing and/or treating the signs of skin dryness. The invention also relates to the use of the protein DJ-1, of polypeptides derived from this protein or of analogues thereof or of a nucleic acid sequence coding for such a polypeptide, as a marker for evaluating the state of dryness of an epithelium.Type: ApplicationFiled: November 19, 2009Publication date: May 10, 2012Applicant: L'OREALInventors: Dominique Bernard, Lucie Simonetti, Isabelle Castiel
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Patent number: 8173144Abstract: Signs of aging of the skin and/or mucous membranes are prevented and/or reduced, and the activity of the proteolytic enzymes of the stratum corneum are stimulated as well, by administering to an individual in need of such treatment, a cosmetic/pharmaceutical composition which comprises a thus effective amount of at least one hydroxylated urea compound having the following formula (I): in which: the radicals R1, R2, R3 and R4, which may be identical or different, are each a hydrogen atom, a C1-C4 alkyl radical or a C2-C6 hydroxyalkyl radical which can contain from 1 to 5 hydroxyl groups, wherein at least one of the R1 to R4 radicals represents a hydroxyalkyl radical, or salt, solvate or isomer thereof, formulated into a physiologically acceptable medium therefor.Type: GrantFiled: October 28, 2005Date of Patent: May 8, 2012Assignee: L'OrealInventors: Dominique Bernard, Lucie Simonetti
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Patent number: 7999008Abstract: The invention relates to the use of at least one urea derivative of the following formula (I) in a composition containing a physiologically acceptable medium, as agent intended for stimulating desquamation of the skin and/or the mucous membranes. It also relates to a method of cosmetic treatment and cosmetic agents containing it.Type: GrantFiled: July 13, 2006Date of Patent: August 16, 2011Assignee: L'OrealInventors: Dominique Bernard, Lucie Simonetti, Pascale Pelletier
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Publication number: 20110098230Abstract: The present invention relates to the use, in particular cosmetic and/or therapeutic use, of annexin II, of polypeptides derived from this protein or of analogues thereof, of a nucleic sequence encoding such a polypeptide or of a modulator of the activity, the stability or the expression of such a polypeptide, in particular for preventing and/or treating the signs of skin dryness. The invention also relates to the use of annexin II, of polypeptides derived from this protein or of analogues thereof, or of a nucleic sequence encoding such a polypeptide, as a marker for evaluating a state of dryness of an epithelium.Type: ApplicationFiled: April 2, 2009Publication date: April 28, 2011Applicant: L'OrealInventors: Dominique Bernard, Lucie Simonetti, Isabelle Castiel
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Publication number: 20110091439Abstract: A method for preventing and/or treating the signs of skin aging comprises administering as an agent into an individual in need thereof an effective amount of acid ceramidase, polypeptides derived from this protein or analogues thereof, a nucleic sequence encoding such a polypeptide, or an agent for modulating the expression or the biological or biochemical activity of such a polypeptide. A methods for characterizing a state of an epithelium comprises determining a content of acid ceramidase, polypeptides derived from this protein or analogues thereof, or a nucleic sequence encoding such a polypeptide in an epidermis sample.Type: ApplicationFiled: December 18, 2008Publication date: April 21, 2011Applicant: L'OREALInventors: Dominique Bernard, Lucie Simonetti, Isabelle Castiel
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Publication number: 20110038830Abstract: The present invention relates to the use, in particular cosmetic and/or therapeutic use, of plakoglobin, of polypeptides derived from this protein or of analogs thereof, of a nucleic sequence encoding such a polypeptide or of an agent for modulating the activity, the stability or the expression of such a polypeptide, in particular for stimulating terminal epithelial differentiation. The invention also relates to the use of plakoglobin, of polypeptides derived from this protein or of analogs thereof, or of a nucleic sequence encoding such a polypeptide, as a marker for evaluating a state of an epithelium.Type: ApplicationFiled: December 19, 2008Publication date: February 17, 2011Applicant: L'OREALInventors: Dominique Bernard, Lucie Simonetti, Isabelle Castel
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Publication number: 20100216707Abstract: The subject of the present invention is the use, in particular the cosmetic and/or therapeutic use, of the apolipoprotein D, of polypeptides derived from this protein or of analogues thereof, of a nucleic sequence encoding such a polypeptide or of an agent modulating the activity or of the expression of such a polypeptide, in particular for stimulating terminal epithelial differentiation. The invention also relates to the use of the protein apolipoprotein D, of polypeptides derived from this protein or of analogues thereof, or of a nucleic sequence encoding such a polypeptide as a marker for evaluating the state of the epidermis.Type: ApplicationFiled: June 20, 2008Publication date: August 26, 2010Applicant: L'OREALInventors: Dominique Bernard, Isabelle Castiel, Lucie Simonetti
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Publication number: 20100216165Abstract: The invention relates to the use of one or more complexed or noncomplexed, soluble peptide form(s) of Desmoglein I, as a marker for evaluating the effectiveness of active agents and/or of treatments, in particular anti-ageing active agents and/or treatments, with regard to an epidermis.Type: ApplicationFiled: January 14, 2010Publication date: August 26, 2010Applicant: L'OREALInventors: MARK DONOVAN, LUCIE SIMONETTI, DOMINIQUE BERNARD
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Publication number: 20100179200Abstract: 2-oxothiazolidine-4-carboxylic acid compounds having the structural formula (I): are suited for promoting desquamation of the skin and/or stimulating epidermal renewal and/or combating aging of the skin.Type: ApplicationFiled: January 6, 2010Publication date: July 15, 2010Applicant: SOCIETE L'OREAL, S.A.Inventors: Jean-Baptiste GALEY, Dominique Bernard, Lucie Simonetti
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Publication number: 20100179222Abstract: Cosmetic or pharmaceutical compositions comprising compounds of formula (I) and the corresponding salts thereof: wherein: R1 is a radical chosen from —COOR?, —CONR?R?, —CH2OR?, —COR?, —CH2R?, —SO2OR?, —PO3R?R? and —NHR?, wherein R? and R?, which may be identical or different, are defined herein; R2 is chosen from saturated and unsaturated, linear, branched and cyclic hydrocarbon radicals comprising from 1 to 18 carbon atoms which are optionally substituted by from 1 to 5 identical or different entities chosen from —OR??, —OCOR??, —SR??, —SCOR??, NR??R??, —NHCOR??, halogen, —CN, —COOR?? and —COR??, wherein R?? and R??, which may be identical or different, are defined herein; as well as the use of these compounds, for example, to promote skin desquamation, to stimulate epidermal renewal and/or to combat the signs of skin ageing.Type: ApplicationFiled: March 22, 2010Publication date: July 15, 2010Inventors: Christophe Boulle, Maria Dalko, Jean-Luc Leveque, Lucie Simonetti
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Publication number: 20100069497Abstract: Cosmetic or pharmaceutical compositions comprising compounds of formula (I) and the corresponding salts thereof: wherein: —R1 is a radical chosen from —COOR?, —CONR?R?, —CH2OR?, —COR?, —CH2R?, —SO2OR?, —PO3R?R? and —NHR?, wherein R? and R?, which may be identical or different, are defined herein; —R2 is chosen from saturated and unsaturated, linear, branched and cyclic hydrocarbon radicals comprising from 1 to 18 carbon atoms which are optionally substituted by from 1 to 5 identical or different entities chosen from —OR??, —OCOR??, —SR??, —SCOR??, NR??R??, —NHCOR??, halogen, —CN, —COOR?? and —COR??, wherein R?? and R??, which may be identical or different, are defined herein; as well as the use of these compounds, for example, to promote skin desquamation, to stimulate epidermal renewal and/or to combat the signs of skin ageing.Type: ApplicationFiled: March 18, 2009Publication date: March 18, 2010Inventors: Christophe BOULLE, Maria Dalko, Jean-Luc Leveque, Lucie Simonetti
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Publication number: 20070232574Abstract: 2-oxothiazolidine-4-carboxylic acid compounds having the structural formula (I): are suited for promoting desquamation of the skin and/or stimulating epidermal renewal and/or combating aging of the skin.Type: ApplicationFiled: May 30, 2007Publication date: October 4, 2007Applicant: SOCIETE L'OREAL, S.A.Inventors: Jean-Baptiste Galey, Dominique Bernard, Lucie Simonetti
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Publication number: 20070134183Abstract: Aminosulfonic acid compounds having the structural formula (I): are suited for promoting desquamation of the skin and/or stimulating epidermal renewal and/or combating aging of the skin.Type: ApplicationFiled: February 5, 2007Publication date: June 14, 2007Applicant: L'OREALInventors: Jean-Baptiste Galey, Dominique Bernard, Lucie Simonetti
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Publication number: 20070014748Abstract: The invention relates to the use of at least one urea derivative of the following formula (I) in a composition containing a physiologically acceptable medium, as agent intended for stimulating desquamation of the skin and/or the mucous membranes. It also relates to a method of cosmetic treatment and cosmetic agents containing it.Type: ApplicationFiled: July 13, 2006Publication date: January 18, 2007Applicant: L'OREALInventors: Dominique Bernard, Lucie Simonetti, Pascale Pelletier