Patents by Inventor Lucio Martinelli
Lucio Martinelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220381692Abstract: A biochip device includes a waveguide, chromophore elements, a diffusing structure, and a sloping surface. The chromophore elements are disposed on a portion of the waveguide and are configured to emit fluorescence in response to excitation by guided light waves transmitted by the waveguide. The diffusing structure is configured to generate guided light waves in the waveguide when illuminated. The sloping surface is sloped relative to a plane of the waveguide and is configured to direct excitation light into the waveguide, and the sloping surface and the waveguide are configured to deflect the excitation light to the diffusing structure to generate guided light waves within the waveguide. The sloping surface may be a face of a prism attached to or integrated with the waveguide, or the sloping surface may be a chamfer formed at an edge of the waveguide.Type: ApplicationFiled: August 9, 2022Publication date: December 1, 2022Applicant: GENEWAVEInventors: Claude WEISBUCH, Lucio MARTINELLI, Henri BENISTY, Christof SCHAFAUER, Gabriel SAGARZAZU, Thierry GACOIN, Mélanie BEDU
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Publication number: 20220381691Abstract: A biochip device includes a stratified structure, a light coupler, and an optofluidic portion. The stratified structure includes a top layer having a refractive index n1, a bottom layer having a refractive index n3, and an intermediate layer between the top and bottom layers having a refractive index n2. The light coupler optically couples a light source and the top layer to generate waves that are guided in a plurality of directions inside the top layer. The optofluidic portion is supported on a surface of the top layer and includes a hybridizing chamber containing a hybridizing solution and pads supported on the surface of the top layer and situated within the hybridizing chamber. Probe molecules are deposited on the pads. The refractive index n2 of the intermediate layer is greater than or equal to a highest index of refraction of the hybridizing chamber and the hybridizing solution.Type: ApplicationFiled: August 9, 2022Publication date: December 1, 2022Applicant: GENEWAVEInventors: Claude WEISBUCH, Lucio MARTINELLI, Henri BENISTY, Christof SCHAFAUER, Gabriel SAGARZAZU, Thierry GACOIN, Mélanie BEDU
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Patent number: 11415514Abstract: A biochip device comprising a substrate constituted by at least one plate of material forming a multimode planar waveguide and carrying chromophore elements suitable for emitting fluorescence in response to excitation by guided waves having an evanescent portion, the device being characterized in that it includes coupling means for coupling excitation light with the waveguide in the form of guided waves, the coupling means being substantially non-directional.Type: GrantFiled: November 30, 2018Date of Patent: August 16, 2022Assignee: Genewave SASInventors: Claude Weisbuch, Lucio Martinelli, Henri Benisty, Christof Schafauer, Gabriel Sagarzazu, Thierry Gacoin, Mélanie Bedu
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Publication number: 20190257756Abstract: A biochip device comprising a substrate constituted by at least one plate of material forming a multimode planar waveguide and carrying chromophore elements suitable for emitting fluorescence in response to excitation by guided waves having an evanescent portion, the device being characterized in that it includes coupling means for coupling excitation light with the waveguide in the form of guided waves, the coupling means being substantially non-directional.Type: ApplicationFiled: April 30, 2019Publication date: August 22, 2019Inventors: Claude WEISBUCH, Lucio MARTINELLI, Henri BENISTY, Christof SCHAFAUER, Gabriel SAGARZAZU, Thierry GACOIN, Mélanie BEDU
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Publication number: 20190178799Abstract: A biochip device comprising a substrate constituted by at least one plate of material forming a multimode planar waveguide and carrying chromophore elements suitable for emitting fluorescence in response to excitation by guided waves having an evanescent portion, the device being characterized in that it includes coupling means for coupling excitation light with the waveguide in the form of guided waves, the coupling means being substantially non-directional.Type: ApplicationFiled: November 30, 2018Publication date: June 13, 2019Inventors: Claude WEISBUCH, Lucio MARTINELLI, Henri BENISTY, Christof SCHAFAUER, Gabriel SAGARZAZU, Thierry GACOIN, Mélanie BEDU
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Patent number: 10184891Abstract: A biochip device comprising a substrate constituted by at least one plate of material forming a multimode planar waveguide and carrying chromophore elements suitable for emitting fluorescence in response to excitation by guided waves having an evanescent portion, the device being characterized in that it includes coupling means for coupling excitation light with the waveguide in the form of guided waves, the coupling means being substantially non-directional.Type: GrantFiled: December 28, 2011Date of Patent: January 22, 2019Assignee: GENEWAVEInventors: Claude Weisbuch, Lucio Martinelli, Henri Benisty, Christof Schafauer, Gabriel Sagarzazu, Thierry Gacoin, Mélanie Bedu
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Publication number: 20140017128Abstract: A biochip device comprising a substrate constituted by at least one plate of material forming a multimode planar waveguide and carrying chromophore elements suitable for emitting fluorescence in response to excitation by guided waves having an evanescent portion, the device being characterized in that it includes coupling means for coupling excitation light with the waveguide in the form of guided waves, the coupling means being substantially non-directional.Type: ApplicationFiled: December 28, 2011Publication date: January 16, 2014Inventors: Claude Weisbuch, Lucio Martinelli, Henri Benisty, Thierry Gacoin, Christof Schafauer, Gabriel Sagarzazu, Mélanie Bedu
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Publication number: 20130230906Abstract: A cartridge for carrying out a method of analyzing the nucleic acids contained in a sample, includes a main body (1) produced in a substrate, in which there are formed at least one reaction chamber (6) and one detection chamber (10) for at least one nucleic acid likely to be contained in the sample, a microfluid circuit including a sample-injection member (7), elements (4 and 13) for respectively injecting fluids into and removing fluids from the cartridge, cavities, fluidic passages (2) and valves capable of closing them. The cartridge further includes (a) a first face known as the actuation face (16), from which the valves of the cartridge are actuated, and (b) a second face, opposite to the actuating face, including the detection chamber (10) for at least one nucleic acid likely to be contained in the sample, this face being known as the detection face (15).Type: ApplicationFiled: November 16, 2011Publication date: September 5, 2013Applicant: GenewaveInventors: Lucio Martinelli, Marc Artigue, Yann Marcy, Christof Schafauer
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Patent number: 8440985Abstract: An imaging method and a device for detecting the fluorescence of a biochip by illuminating chromophores associated with probes (14) of a substrate (12) placed on a sensor (10) having photodetectors, e.g. of the CCD or CMOS type, a stop filter that rejects the excitation light of the chromophores being provided between the probes (14) and the sensor, the substrate (12) being separable from the sensor (10) after use so as to enable the sensor to be reused.Type: GrantFiled: June 23, 2009Date of Patent: May 14, 2013Assignee: GenewaveInventors: Lucio Martinelli, Yann Marcy, Henri Benisty
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Publication number: 20110266460Abstract: An imaging method and a device for detecting the fluorescence of a biochip by illuminating chromophores associated with probes (14) of a substrate (12) placed on a sensor (10) having photodetectors, e.g. of the CCD or CMOS type, a stop filter that rejects the excitation light of the chromophores being provided between the probes (14) and the sensor, the substrate (12) being separable from the sensor (10) after use so as to enable the sensor to be reused.Type: ApplicationFiled: June 23, 2009Publication date: November 3, 2011Inventors: Lucio Martinelli, Yann Marcy, Henri Benisty