Patents by Inventor Ludwig Lehle

Ludwig Lehle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Yeast host strains with defects in N-glycosylation
    Patent number: 5798226
    Abstract: Saccharomyces mutants with defects in N-glycosylation which are obtainable by ?.sup.3 H!-mannose suicide selection, introduction of one or several selective markers, selection of those strains which, after transformation with the plasmid YEpL/glucose oxidase, secrete 10 mg/l glucose oxidase or more into the culture medium after culture under standard conditions, are allelic to the ngd mutations in Saccharomyces cerevisiae, DSM 7042, DSM 7338, DSM 7160 and/or 7340 and express proteins with a uniform carbohydrate structure.
    Type: Grant
    Filed: May 31, 1996
    Date of Patent: August 25, 1998
    Assignee: Boehringer Mannheim GmbH
    Inventors: Ludwig Lehle, Klaus Lehnert, Erhard Kopetzki
  • Proteins from yeast host strains with defects in N-glycosylation
    Patent number: 5705616
    Abstract: Saccharomyces mutants with defects in N-glycosylation which are obtainable by ?.sup.3 H!-mannose suicide selection, introduction of one or several selective markers, selection of those strains which, after transformation with the plasmid YEpL/glucose oxidase, secrete 10 mg/l GOD or more into the culture medium after culture under standard conditions, are allelic to the ngd mutations in Saccharomyces cerevisiae, DSM 7042, DSM 7338, DSM 7160 and/or 7340 and express proteins with a uniform carbohydrate structure.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: January 6, 1998
    Assignee: Boehringer Mannheim GmbH
    Inventors: Ludwig Lehle, Klaus Lehnert, Erhard Kopetzki