Patents by Inventor Ludwig Ross
Ludwig Ross has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230401458Abstract: An artificial intelligence (AI) system classifies a document by a document type and determines redlining for the document based on the classified document type. The AI system may use machine learning to classify the document, where the AI system trains a machine-learned model using training documents of respective types. After determining the document type of a target document, the AI system compares the target document against one or more templates of the classified document type to determine edited or unedited portions of the target document. The AI system can modify an unedited portion of the target document using a predetermined edit associated with a template. The modified document target document may be displayed at a client device such that the edits (e.g., the modified unedited portion and existing edits in the target document) are visually distinct from one another.Type: ApplicationFiled: June 8, 2022Publication date: December 14, 2023Inventors: Michael Ludwig Ross, Alexander Dylan Sugar, Gurinder Singh Sangha
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Publication number: 20230072925Abstract: An artificial intelligence (AI) system accesses training text documents and parses the training text documents to extract training edits. The AI system forms a set of training data that includes the training text documents and the training edits. The AI system trains an AI model based on at least the set of training data. The AI system may also use a reference model, a general model, and/or user input to generate the AI model. In some embodiments, the training text documents are associated with a type of transaction and the AI model is specific to the type of transaction. The AI system applies the AI model to a target text document to generate target edits. The AI system further modifies the target text document to include the target edits and transmits the modified target text document to a client device.Type: ApplicationFiled: September 7, 2021Publication date: March 9, 2023Inventors: Michael Ludwig Ross, Alexander Dylan Sugar, Gurinder Singh Sangha
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Patent number: 10961246Abstract: The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein fluorine-18 is covalently linked to the glutamate portion of a folate or derivative thereof, a method of their preparation, as well as their use in diagnosis and monitoring of therapy of cancer and inflammatory and autoimmune diseases.Type: GrantFiled: September 21, 2017Date of Patent: March 30, 2021Assignee: MERCK & CIEInventors: Roger Schibli, Rudolf Moser, Cristina Magdalena Muller, Simon Mensah Ametamey, Tobias Ludwig Ross, Viola Groehn
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Patent number: 10377756Abstract: The present invention is directed towards a new method of synthesis of 18F-folate radiopharmaceuticals, wherein fluorine-18 is attached to a pteroate (or folate) or derivative thereof, through direct radiolabeling with 18[F]fluoride, as well as 18F-folate radiopharmaceuticals obtained by such method of synthesis and their use in diagnosis and monitoring of cancer therapy and therapy of inflammatory and autoimmune diseases.Type: GrantFiled: July 13, 2015Date of Patent: August 13, 2019Assignee: MERCK & CIEInventors: Simon Mensah Ametamey, Rudolf Moser, Tobias Ludwig Ross, Phoebe Lam, Viola Groehn
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Publication number: 20180072734Abstract: The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein fluorine-18 is covalently linked to the glutamate portion of a folate or derivative thereof, a method of their preparation, as well as their use in diagnosis and monitoring of therapy of cancer and inflammatory and autoimmune diseases.Type: ApplicationFiled: September 21, 2017Publication date: March 15, 2018Applicant: MERCK & CIEInventors: Roger SCHIBLI, Rudolf MOSER, Cristina Magdalena MULLER, Simon Mensah AMETAMEY, Tobias Ludwig ROSS, Viola GROEHN
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Patent number: 9771368Abstract: The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein the fluorine-18 is covalently linked to the aminobenzoyl moiety, which connects the condensed pyrimidine heterocycle to the amino acid portion within folate structures, as well as their precursors and their non-radioactive references, a method of their preparation, as well as their use in diagnosis of a cell or population of cells expressing a folate-receptor and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.Type: GrantFiled: February 12, 2016Date of Patent: September 26, 2017Assignee: MERCK & CIEInventors: Simon Mensah Ametamey, Rudolf Moser, Tobias Ludwig Ross, Viola Groehn
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Publication number: 20160159802Abstract: The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein the fluorine-18 is covalently linked to the aminobenzoyl moiety, which connects the condensed pyrimidine heterocycle to the amino acid portion within folate structures, as well as their precursors and their non-radioactive references, a method of their preparation, as well as their use in diagnosis of a cell or population of cells expressing a folate-receptor and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.Type: ApplicationFiled: February 12, 2016Publication date: June 9, 2016Applicant: MERCK & CIEInventors: Simon Mensah AMETAMEY, Rudolf MOSER, Tobais Ludwig ROSS, Viola GROEHN
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Patent number: 9315506Abstract: The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein the fluorine-18 is covalently linked to the aminobenzoyl moiety, which connects the condensed pyrimidine heterocycle to the amino acid portion within folate structures, as well as their precursors and their non-radioactive references, a method of their preparation, as well as their use in diagnosis of a cell or population of cells expressing a folate-receptor and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.Type: GrantFiled: April 11, 2008Date of Patent: April 19, 2016Assignee: MERCK & CIEInventors: Simon Mensah Ametamey, Rudolf Moser, Tobias Ludwig Ross, Viola Groehn
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Publication number: 20150315189Abstract: The present invention is directed towards a new method of synthesis of 18F-folate radiopharmaceuticals, wherein fluorine-18 is attached to a pteroate (or folate) or derivative thereof, through direct radiolabeling with 18[F]fluoride, as well as 18F-folate radiopharmaceuticals obtained by such method of synthesis and their use in diagnosis and monitoring of cancer therapy and therapy of inflammatory and autoimmune diseases.Type: ApplicationFiled: July 13, 2015Publication date: November 5, 2015Applicant: MERCK & CIEInventors: Simon Mensah AMETAMEY, Rudolf MOSER, Tobias Ludwig ROSS, Phoebe LAM, Viola GROEHN
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Patent number: 9069134Abstract: An optical assembly, which is in particular in the form of a splitter component with a so-called splitter forming a passive optical component, is produced particularly inexpensively. In a first step a plurality of splitters are produced on a common wafer by forming a corresponding conductor track pattern. In a second step optical fibers are coupled simultaneously to the connection sides of the individual splitters with the aid of a connection carrier. Then, in a third step the individual splitters with the connection carriers connected thereto are separated form one another. Only one common coupling operation for a large number of splitters is required. The splitters may then be connected to form a splitter cascade.Type: GrantFiled: May 16, 2012Date of Patent: June 30, 2015Assignee: Leoni Kabel Holding GmbHInventors: Ludwig Ross, Stefan Kufner, Maria Kufner, Wolfgang Foss, Marco Bock, Frank Baetz
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Patent number: 8344140Abstract: The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein fluorine-18 is covalently linked through a triazole- or tetrazole linker to a folate or derivative thereof, a method of their preparation, as well as their use in diagnosis and monitoring of therapy of cancer and inflammatory and autoimmune diseases.Type: GrantFiled: April 11, 2008Date of Patent: January 1, 2013Assignee: Merck Eprova AGInventors: Simon Mensah Ametamey, Rudolf Moser, Tobias Ludwig Ross, Thomas Leighton Mindt, Viola Groehn
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Publication number: 20120237161Abstract: An optical assembly, which is in particular in the form of a splitter component with a so-called splitter forming a passive optical component, is produced particularly inexpensively. In a first step a plurality of splitters are produced on a common wafer by forming a corresponding conductor track pattern. In a second step optical fibers are coupled simultaneously to the connection sides of the individual splitters with the aid of a connection carrier. Then, in a third step the individual splitters with the connection carriers connected thereto are separated form one another. Only one common coupling operation for a large number of splitters is required. The splitters may then be connected to form a splitter cascade.Type: ApplicationFiled: May 16, 2012Publication date: September 20, 2012Applicant: LEONI KABEL HOLDING GMBHInventors: LUDWIG ROSS, STEFAN KUFNER, MARIA KUFNER, WOLFGANG FOSS, MARCO BOCK, FRANK BAETZ
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Publication number: 20110286921Abstract: The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein fluorine-18 is covalently linked to the glutamate portion of a folate or derivative thereof, a method of their preparation, as well as their use in diagnosis and monitoring of therapy of cancer and inflammatory and autoimmune diseases.Type: ApplicationFiled: October 12, 2009Publication date: November 24, 2011Applicant: MERCK & CIEInventors: Roger Schibli, Rudolf Moser, Cristina Magdalena Muller, Simon Mensah Ametamey, Tobias Ludwig Ross, Viola Groehn
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Publication number: 20100111863Abstract: The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein fluorine-18 is covalently linked through a triazole- or tetrazole linker to a folate or derivative thereof, a method of their preparation, as well as their use in diagnosis and monitoring of therapy of cancer and inflammatory and autoimmune diseases.Type: ApplicationFiled: April 11, 2008Publication date: May 6, 2010Applicant: Merck Eprova AGInventors: Simon Mensah Ametamey, Rudolf Moser, Tobias Ludwig Ross, Thomas Leighton Mindt, Viola Groehn
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Publication number: 20100111864Abstract: The present invention is directed towards a new method of synthesis of 18F-folate radiopharmaceuticals, wherein fluorine-18 is attached to a pteroate (or folate) or derivative thereof, through direct radiolabeling with 18[F]fluoride, as well as 18F-folate radiopharmaceuticals obtained by such method of synthesis and their use in diagnosis and monitoring of cancer therapy and therapy of inflammatory and autoimmune diseases.Type: ApplicationFiled: April 11, 2008Publication date: May 6, 2010Applicant: MERCK EPROVA AGInventors: Simon Mensah Ametamey, Rudolf Moser, Tobias Ludwig Ross, Phoebe Lam, Viola Groehn
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Publication number: 20100056533Abstract: The present invention is directed towards new 18F-folate radio-pharmaceuticals, wherein the fluorine-18 is covalently linked to the aminobenzoyl moiety, which connects the condensed pyrimidine heterocycle to the amino acid portion within folate structures, as well as their precursors and their non-radioactive references, a method of their preparation, as well as their use in diagnosis of a cell or population of cells expressing a folate-receptor and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.Type: ApplicationFiled: April 11, 2008Publication date: March 4, 2010Applicant: Merck Eprova AGInventors: Simon Mensah Ametamey, Rudolf Moser, Tobias Ludwig Ross, Viola Groehn
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Patent number: 5114453Abstract: A method of production of mono- or multimodal lightwave guides from special substrate glasses of the glass system SiO.sub.2 -B.sub.2 O.sub.3 -Al.sub.2 O.sub.3 - K.sub.2 O-F.sup.-, with partial exchange of the Li.sup.+, Na.sup.+, and/or K.sup.+ ions present in the glass against Cs.sup.+ ions, the substrate glasses having the following compositions (in mol.-%): SiO.sub.2 45-72, B.sub.2 O.sub.3 8-25, Al.sub.2 O.sub.3 1-25, Li.sub.2 O 0-1, Na.sub.2 O 0-2, K.sub.2 O 6-18, MO 0-1 (MO= MgO, CaO, SrO, BaO, ZnO, PbO), in which a portion of the O.sup.- ions present in the glass are replaced by 1-15 mol % F.sup.- ions.Type: GrantFiled: November 27, 1990Date of Patent: May 19, 1992Assignee: Schott GlaswerkeInventors: Ludwig Ross, Werner Schumann
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Patent number: 5004707Abstract: Production of mono- or multimodal lightwave guides from special substrate glasses of the glass system SiO.sub.2 --B.sub.2 O.sub.3 --Al.sub.2 O.sub.3 -- K.sub.2 O--F.sup.-, with partial exchange of the Li.sup.+, Na.sup.+, and/or K.sup.+ ions present in the glass against Cs.sup.+ ions, the substrate glasses having the following compositions (in mol.-%): SiO.sub.2 45-72, B.sub.2 O.sub.3 8-25, Al.sub.2 O.sub.3 1-25, Li.sub.2 O 0-1, Na.sub.2 O 0-2, K.sub.2 O 6-18, MO 0-1 (MO=MgO, CaO, SrO, BaO, ZnO, PbO), in which a portion of the O.sup.- ions present in the glass are replaced by 1-15 mol % F.sup.- ions.Type: GrantFiled: November 16, 1989Date of Patent: April 2, 1991Assignee: Schott GlaswerkeInventors: Ludwig Ross, Werener Schumann
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Patent number: 4824809Abstract: A new, CdO-and ThO.sub.2 -free optical glass with refractive indices of 1.73-1.78 and Abbe numbers of 30-34 and with particularly good devitrification stability comprises (in weight %):______________________________________ SiO.sub.2 12-20, B.sub.2 O.sub.3 10-18, PbO 50-60 Al.sub.2 O.sub.3 2-7, ZnO 0-4, ZrO.sub.2 0.5-3 La.sub.2 O.sub.3 2-10, Cs.sub.2 O 0-5, M.sub.2 O 0-1 (M.sub.2 O.dbd. Na.sub.2 O, K.sub.2 O, Li.sub.2 O) TiO.sub.2 0-5 with the SiO.sub.2 /B.sub.2 O.sub.3 -ratio being about 1.0 to ______________________________________ 1.5.Type: GrantFiled: December 28, 1987Date of Patent: April 25, 1989Assignee: Schott GlaswerkeInventors: Danuta Grabowski, Ludwig Ross
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Patent number: 4814299Abstract: An optical glass, n.sub.d .gtoreq.1.60 and v.sub.d .gtoreq.58, having a high chemical stability as well as resistance to phase separation and crystallization, comprises in percent by weight:______________________________________ SiO.sub.2 21.5-27.0; B.sub.2 O.sub.3 23.5-30.0 SrO 16.0-24.0; La.sub.2 O.sub.3 10.0-20; Al.sub.2 O.sub.3 1.5-5.0; BaO 5.0-14.0; ZrO.sub.2 0-4.0; Li.sub.2 O 0.5-5.0; Na.sub.2 O 0.8-2.5; K.sub.2 O 0-2.0.Type: GrantFiled: July 2, 1987Date of Patent: March 21, 1989Assignee: Schott GlaswerkeInventors: Ludwig Ross, Volkmar Geiler