Patents by Inventor Luigi Moro

Luigi Moro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11938141
    Abstract: The present invention refers to a new enzymatic process for obtaining 17?-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17?,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17?-propionate and 9,11-dehydro-cortexolone 17?-butanoate.
    Type: Grant
    Filed: November 18, 2021
    Date of Patent: March 26, 2024
    Assignee: CASSIOPEA S.P.A.
    Inventors: Mauro Ajani, Luigi Moro
  • Publication number: 20230135346
    Abstract: Oral pharmaceutical compositions containing rifamycin SV, or a pharmaceutically salt thereof, characterized in that they are formulated in a higher strength (about 600 mg/tablet) and in such a manner to obtain a modified profile of the rifamycin SV, or a pharmaceutically acceptable salt thereof, in the proximal portion of the intestine, i.e. in the small intestine (duodenum, jejunum and ileum). In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of small intestine bacterial overgrowth (SIBO) and/or irritable bowel syndrome (IBS) and/or in the treatment of cholera. In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of hepatic encephalopathy, hepatic cirrhosis, pouchitis and/or spontaneous bacterial perotinitis.
    Type: Application
    Filed: December 27, 2022
    Publication date: May 4, 2023
    Applicant: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi MORO, Luigi Maria LONGO
  • Publication number: 20230130628
    Abstract: Herein described are solid oral compositions of dyes for use in diagnostic endoscopy, preferably colon endoscopy.
    Type: Application
    Filed: December 20, 2022
    Publication date: April 27, 2023
    Applicant: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi MORO, Alessandro REPICI
  • Publication number: 20230104965
    Abstract: The present invention refers to a new enzymatic process for obtaining 17?-monoesters of cortexolone and/or its 9, 11-dehydroderivatives starting from the corresponding 17?,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17?-propionate and 9,11-dehydro-cortexolone 17?-butanoate.
    Type: Application
    Filed: November 18, 2022
    Publication date: April 6, 2023
    Applicant: CASSIOPEA S.P.A.
    Inventors: Mauro AJANI, Luigi MORO
  • Patent number: 11564883
    Abstract: Oral pharmaceutical compositions containing rifamycin SV, or a pharmaceutically salt thereof, characterized in that they are formulated in a higher strength (about 600 mg/tablet) and in such a manner to obtain a modified profile of the rifamycin SV, or a pharmaceutically acceptable salt thereof, in the proximal portion of the intestine, i.e. in the small intestine (duodenum, jejunum and ileum). In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of small intestine bacterial overgrowth (SIBO) and/or irritable bowel syndrome (IBS) and/or in the treatment of cholera. In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of hepatic encephalopathy, hepatic cirrhosis, pouchitis and/or spontaneous bacterial perotinitis.
    Type: Grant
    Filed: November 7, 2018
    Date of Patent: January 31, 2023
    Assignee: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi Moro, Luigi Maria Longo
  • Publication number: 20220280531
    Abstract: The present invention refers to a new enzymatic process for obtaining 17?-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17?,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17?-propionate and 9,11-dehydro-cortexolone 17?-butanoate.
    Type: Application
    Filed: November 18, 2021
    Publication date: September 8, 2022
    Applicant: CASSIOPEA S.P.A.
    Inventors: Mauro AJANI, Luigi MORO
  • Patent number: 11207332
    Abstract: The present invention refers to a new enzymatic process for obtaining 17?-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17?,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17?-propionate and 9,11-dehydro-cortexolone 17?-butanoate.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: December 28, 2021
    Assignee: Cassiopea S.P.A.
    Inventors: Mauro Ajani, Luigi Moro
  • Patent number: 11123460
    Abstract: The invention provides a pharmaceutical composition in form of emulsion or microemulsion for use in an endoscopic procedure, preferably said endoscopic procedure comprising the administration of said pharmaceutical composition to a human with the aim of improving and facilitating the resection of the lesion by raising the area where the lesion is located. The invention herein disclosed provides a method for performing an endoscopic procedure, said method preferably comprising the administration of a pharmaceutical composition in form of emulsion or microemulsion to a human.
    Type: Grant
    Filed: October 25, 2019
    Date of Patent: September 21, 2021
    Assignee: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi Maria Longo, Luigi Moro, Enrico Frimonti, Alessandro Repici
  • Patent number: 10925978
    Abstract: The present invention provides a novel liquid composition in the form of an emulsion or microemulsion for rectal administration comprising at least one dye, at least one emulsifier, and at least one physiologically acceptable excipient, and its use in a diagnostic endoscopic procedure of sigmoid colon and/or rectum. Preferably, said diagnostic endoscopic procedure of sigmoid colon and/or rectum is an anoscopy, a proctoscopy, a rectoscopy and/or a sigmoidoscopy.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: February 23, 2021
    Assignee: COSMO TECHNOLOGIES LIMITED
    Inventors: Luigi Moro, Enrico Frimonti, Luigi Maria Longo
  • Patent number: 10849979
    Abstract: The present invention relates to a pharmaceutical composition in form of emulsion or microemulsion and the use thereof as aid during endoscopic procedures in which it is injected in a target tissue in order to form a cushion. More in details, the invention relates to a method for performing an endoscopic procedure, which comprises injecting said pharmaceutical composition in form of emulsion or microemulsion in a target tissue of a patient, in order to form a cushion, which cushion is then optionally subjected to an endoscopic surgical procedure, such as a resection.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: December 1, 2020
    Assignee: COSMO TECHNOLOGIES LIMITED
    Inventors: Luigi Moro, Luigi Maria Longo, Enrico Frimonti, Alessandro Repici
  • Publication number: 20200281850
    Abstract: Oral pharmaceutical compositions containing rifamycin SV, or a pharmaceutically salt thereof, characterized in that they are formulated in a higher strength (about 600 mg/tablet) and in such a manner to obtain a modified profile of the rifamycin SV, or a pharmaceutically acceptable salt thereof, in the proximal portion of the intestine, i.e. in the small intestine (duodenum, jejunum and ileum). In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of small intestine bacterial overgrowth (SIBO) and/or irritable bowel syndrome (IBS) and/or in the treatment of cholera. In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of hepatic encephalopathy, hepatic cirrhosis, pouchitis and/or spontaneous bacterial perotinitis.
    Type: Application
    Filed: November 7, 2018
    Publication date: September 10, 2020
    Applicant: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi MORO, Luigi Maria LONGO
  • Publication number: 20200268909
    Abstract: The present application discloses solid compositions for the oral administration of dyes, and diagnostic use thereof. Preferably, such diagnostic use is aimed at the diagnostic evaluation of the gastrointestinal tract.
    Type: Application
    Filed: September 27, 2019
    Publication date: August 27, 2020
    Applicant: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi MORO, Mauro Severino AJANI, Roberto VILA, Giuseppe CELASCO, Alessandro REPICI
  • Patent number: 10716796
    Abstract: The present invention refers to a new enzymatic process for obtaining 17?-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17?,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17?-propionate and 9,11-dehydro-cortexolone 17?-butanoate.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: July 21, 2020
    Assignee: CASSIOPEA S.P.A.
    Inventors: Mauro Ajani, Luigi Moro
  • Publication number: 20200163888
    Abstract: The present disclosure relates to methods for treating intestinal diseases presenting at least one inflammatory component such as inflammatory bowel disease or diverticular disease and/or maintaining remission of intestinal diseases presenting at least one inflammatory component such as inflammatory bowel disease (IBD) or diverticular disease using budesonide MMX compositions.
    Type: Application
    Filed: August 6, 2019
    Publication date: May 28, 2020
    Applicants: COSMO TECHNOLOGIES LIMITED, SANTARUS, INC.
    Inventors: Gerald Thomas PROEHL, Wendell WIERENGA, Michael Fangching HUANG, Emerson David BALLARD, II, Luigi MORO
  • Publication number: 20200155572
    Abstract: The present invention refers to a new enzymatic process for obtaining 17?-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17?,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17?-propionate and 9,11-dehydro-cortexolone 17?-butanoate.
    Type: Application
    Filed: November 18, 2019
    Publication date: May 21, 2020
    Applicant: Cassiopea S.P.A.
    Inventors: Mauro AJANI, Luigi MORO
  • Publication number: 20200129643
    Abstract: Herein described are solid oral compositions of dyes for use in diagnostic endoscopy, preferably colon endoscopy.
    Type: Application
    Filed: June 12, 2019
    Publication date: April 30, 2020
    Applicant: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi Moro, Alessandro Repici
  • Publication number: 20200061212
    Abstract: The present invention relates to methods for improving the detection of pathologies in the colon and method of flagging the mucosal lesions in the colon.
    Type: Application
    Filed: November 28, 2017
    Publication date: February 27, 2020
    Applicant: COSMO TECHNOLOGIES LTD.
    Inventor: Luigi MORO
  • Publication number: 20200054797
    Abstract: The invention provides a pharmaceutical composition in form of emulsion or microemulsion for use in an endoscopic procedure, preferably said endoscopic procedure comprising the administration of said pharmaceutical composition to a human with the aim of improving and facilitating the resection of the lesion by raising the area where the lesion is located. The invention herein disclosed provides a method for performing an endoscopic procedure, said method preferably comprising the administration of a pharmaceutical composition in form of emulsion or microemulsion to a human.
    Type: Application
    Filed: October 25, 2019
    Publication date: February 20, 2020
    Applicant: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi Maria LONGO, Luigi MORO, Enrico FRIMONTI, Alessandro REPICI
  • Publication number: 20200000926
    Abstract: The present invention relates to a pharmaceutical composition in form of emulsion or microemulsion and the use thereof as aid during endoscopic procedures in which it is injected in a target tissue in order to form a cushion. More in details, the invention relates to a method for performing an endoscopic procedure, which comprises injecting said pharmaceutical composition in form of emulsion or microemulsion in a target tissue of a patient, in order to form a cushion, which cushion is then optionally subjected to an endoscopic surgical procedure, such as a resection.
    Type: Application
    Filed: August 9, 2019
    Publication date: January 2, 2020
    Applicant: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi MORO, Luigi Maria LONGO, Enrico FRIMONTI, Alessandro REPICI
  • Patent number: 10413611
    Abstract: The present invention relates to a pharmaceutical composition in form of emulsion or microemulsion and the use thereof as aid during endoscopic procedures in which it is injected in a target tissue in order to form a cushion. More in details, the invention relates to a method for performing an endoscopic procedure, which comprises injecting said pharmaceutical composition in form of emulsion or microemulsion in a target tissue of a patient, in order to form a cushion, which cushion is then optionally subjected to an endoscopic surgical procedure, such as a resection.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: September 17, 2019
    Assignee: COSMO TECHNOLOGIES LIMITED
    Inventors: Luigi Moro, Luigi Maria Longo, Enrico Frimonti, Alessandro Repici