Patents by Inventor Luis De Lecea

Luis De Lecea has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINED ULTRASONIC STIMULATION AND PHOTOMETRY DEVICE
    Publication number: 20220378360
    Abstract: Devices and methods are disclosed related to combined ultrasonic stimulation and photometry. A device can include an ultrasonic transducer and an optical delivery element integrated with the ultrasonic transducer. The ultrasonic transducer can deliver ultrasound energy at a tip of the optical delivery element. In certain embodiments, the optical delivery element can be an optical fiber. A detector can generate an indication of a cell response associated with the delivered ultrasound energy.
    Type: Application
    Filed: November 12, 2020
    Publication date: December 1, 2022
    Inventors: George Quintin STEDMAN, Kamyar FIROUZI, Butrus T. KHURI-YAKUB, Luis DE LECEA, Keith Richard MURPHY
  • Cortistatin: neuropeptides, compositions and methods
    Publication number: 20060047107
    Abstract: The present invention relates generally to nucleic acids encoding a novel neuropeptide designated cortistatin. The cortistatin nucleic acids, proteins and polypeptides thereof along with anti-cortistatin antibodies are useful in both screening methods, diagnostic methods and therapeutic methods related to modulation of sleep and disorders thereof.
    Type: Application
    Filed: May 10, 2005
    Publication date: March 2, 2006
    Applicant: The Scripps Research Institute
    Inventors: J. Sutcliffe, Luis De Lecea, Steven Henriksen, George Siggins
  • Cortistatin: neuropeptides, compositions and methods
    Publication number: 20050249734
    Abstract: The present invention relates generally to nucleic acids encoding a novel neuropeptide designated cortistatin, anti-cortistatin antibodies and pharmaceutical compositions thereof. The cortistatin nucleic acids, proteins and polypeptides along with anti-cortistatin antibodies are useful in both screening methods, diagnostic methods and therapeutic methods related to modulation of sleep and disorders thereof.
    Type: Application
    Filed: October 14, 2004
    Publication date: November 10, 2005
    Inventors: J. Sutcliffe, Luis De Lecea, Steven Henriksen, George Siggins
  • Antibodies to cortistatin: neuropeptides, compositions and methods
    Patent number: 6814967
    Abstract: The present invention relates generally to nucleic acids encoding a novel neuropeptide designated cortistatin. The cortistatin nucleic acids, proteins and polypeptides thereof along with anti-cortistatin antibodies are useful in both screening methods, diagnostic methods and therapeutic methods related to modulation of sleep and disorders thereof.
    Type: Grant
    Filed: January 18, 2001
    Date of Patent: November 9, 2004
    Assignee: The Scripps Research Institute
    Inventors: J. Gregor Sutcliffe, Luis De Lecea, Steven J. Henriksen, George R. Siggins
  • Hypothalamus-specific polypeptides
    Patent number: 6635479
    Abstract: Disclosed are hypocretin polynucleotides and hypocretin polypeplides, as well as antibodies, oligonucleotides, diagnostic kits and methods, and therapeutic compositions and methods. Hypocretin, one of several novel liypothalamic-specific polypeptides identified isolated and sequenced, is localized to regions of the hypothalamus involved in appetite and feeding behavior. Hypocretin polypeptides are biologically active, producing electrical changes in neurons, lowering body temperature and reducing food intake.
    Type: Grant
    Filed: February 2, 1999
    Date of Patent: October 21, 2003
    Assignee: The Scripps Research Institute
    Inventors: J. Gregor Sutcliffe, Kaare M. Gautvik, Luis De Lecea, Floyd E. Bloom, Patria E. Danielson, Vigdis T. Gautvik, Thomas S. Kilduff, Pamela E. Foye
  • Hypothalamus-specific polypeptides
    Publication number: 20030176666
    Abstract: Peptides and polypeptides found in the hypothalamus region of the mammalian brain are described, particularly hypocretin polypeptides and their uses. Hypocretin polypeptides are biologically active and produce electrical changes in neurons, lower body temperature, and reduce food intake.
    Type: Application
    Filed: December 12, 2000
    Publication date: September 18, 2003
    Applicant: The Scripps Research Institute
    Inventors: J. Gregor Sutcliffe, Kaare M. Gautvik, Luis De Lecea, Floyd E. Bloom, Patria E. Danielson, Vigdis T. Gautvik, Thomas S. Kilduff, Pamela E. Foye
  • Cortistatin: neuropeptides
    Patent number: 6479642
    Abstract: The present invention relates generally to nucleic acids encoding a novel neuropeptide designated cortistatin. The cortistatin nucleic acids, proteins and polypeptides thereof along with anti-cortistatin antibodies are useful in both screening methods, diagnostic methods and therapeutic methods related to modulation of sleep and disorders thereof.
    Type: Grant
    Filed: May 15, 1997
    Date of Patent: November 12, 2002
    Assignee: The Scripps Research Institute
    Inventors: J. Gregor Sutcliffe, Luis De Lecea, Steven J. Henriksen, George R. Siggins
  • Cortistatin: neuropeptides, compositions and methods
    Publication number: 20020133000
    Abstract: The present invention relates generally to nucleic acids encoding a novel neuropeptide designated cortistatin. The cortistatin nucleic acids, proteins and polypeptides thereof along with anti-cortistatin antibodies are useful in both screening methods, diagnostic methods and therapeutic methods related to modulation of sleep and disorders thereof.
    Type: Application
    Filed: January 30, 2002
    Publication date: September 19, 2002
    Inventors: J. Gregor Sutcliffe, Luis De Lecea, Steven J. Henriksen, George R. Siggins
  • Cortistatin: neuropeptides, compositions and methods
    Publication number: 20020013456
    Abstract: The present invention relates generally to nucleic acids encoding a novel neuropeptide designated cortistatin. The cortistatin nucleic acids, proteins and polypeptides thereof along with anti-cortistatin antibodies are useful in both screening methods, diagnostic methods and therapeutic methods related to modulation of sleep and disorders thereof.
    Type: Application
    Filed: January 18, 2001
    Publication date: January 31, 2002
    Applicant: The Scripps Research Institute
    Inventors: J. Gregor Sutcliffe, Luis De Lecea, Steven J. Henriksen, George R. Siggins
  • Cortistatin: nucleic acids that encode these neuropeptides
    Patent number: 6074872
    Abstract: The present invention relates generally to nucleic acids encoding a novel neuropeptide designated cortistatin. The cortistatin nucleic acids, proteins and polypeptides thereof along with anti-cortistatin antibodies are useful in both screening methods, diagnostic methods and therapeutic methods related to modulation of sleep and disorders thereof.
    Type: Grant
    Filed: May 15, 1996
    Date of Patent: June 13, 2000
    Assignee: The Scripps Research Institute
    Inventors: J. Gregor Sutcliffe, Luis de Lecea