Patents by Inventor Luis Maria Mir

Luis Maria Mir has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8705223
    Abstract: The present disclosure relates to a method for producing an insulated electrode comprising a conductive material coated with an electrically insulating material. The method includes at least the following steps of: forming a mold in an electrically insulating material, the mold including at least one channel, the mold being adapted to confine a conductive material, introducing the conductive material in a liquid state into the channel of the mold, the conductive material having a melting point that is lower than the melting point of the electrically insulating material.
    Type: Grant
    Filed: August 20, 2009
    Date of Patent: April 22, 2014
    Assignees: Centre National de la Recherche Scientifique (CNRS), Ecole Normale Superieure de Cachan, Institut Gustave-Roussy
    Inventors: Julien Villemejane, Bruno Le Pioufle, Luis Maria Mir, Olivier Francais, Jean-Pierre Lefevre
  • Publication number: 20110141649
    Abstract: The present disclosure relates to a method for producing an insulated electrode comprising a conductive material coated with an electrically insulating material.
    Type: Application
    Filed: August 20, 2009
    Publication date: June 16, 2011
    Inventors: Julien Villemejane, Bruno Le Pioufle, Luis Maria Mir, Olivier Francais, Jean-Pierre Lefevre
  • Publication number: 20110118811
    Abstract: The present disclosure relates to the delivery of electric pulses any organic or inorganic conductive material and/or any biological material and/or to cells in vivo, ex vivo or in vitro, for example for the electroporation of the cells, for the electrically mediated transfer gene transfer of nucleic acids into tissue cell using a pulsed electric field and/or for the electromanipulation, in general, of the cell membrane or of the cell inside. The electric pulse applicator for the treatment of a conductive material such as biological material allowing an electric field to be applied to said conductive material in such a way as to modify it properties, includes at least one electrode including a conductive main body and an electrically insulating coating intended to be introduced into and/or at the vicinity of the conductive material to be treated, and a pulse generator sending pulses to the electrodes having a slope (dE/dt) greater than 1015 V/m/s.
    Type: Application
    Filed: July 21, 2009
    Publication date: May 19, 2011
    Inventors: Julien VillemeJane, Bruno Le Pioufle, Luis Maria Mir
  • Publication number: 20090163868
    Abstract: Fluid dispensing system comprising a system of interconnected micro chambers (13) communicating with at least a fluid inlet (22) and with at least a suction port (26). Each micro chamber (13) has an output communicating with a needle (15) and has at least one side defined by a deformable membrane (34) subjected to a variable pressure so that a decrease of the pressure with respect to the pressure present at fluid inlet (22) is transferred to the system of micro chambers (13) through the suction port (26) thereby establishing a suction of fluid from the inlet (22) towards the chambers (13) that are filled. An increase of the pressure, causing the deflection of the membrane (34) towards the inner side of each micro chamber, will close each dispensing unit and provoke the ejection of the fluid contained in each chamber (13) of the dispensing unit content through the outlets.
    Type: Application
    Filed: May 2, 2007
    Publication date: June 25, 2009
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Antonin Hoël, Marie-Caroline Jullien, Luis Maria Mir