Patents by Inventor Luis Richardo Simoes da Silva Graca

Luis Richardo Simoes da Silva Graca has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic antibodies
    Patent number: 10800850
    Abstract: A pharmaceutical comprising a therapeutic protein that binds to a therapeutic target, the protein being modified with a compound that inhibits binding of the protein to the therapeutic target, the modified protein being effective for reducing an immune response against the protein and for producing a therapeutic effect by binding to the therapeutic target. The therapeutic protein may be an antibody that includes an antibody combining site that binds to the therapeutic target.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: October 13, 2020
    Assignee: CytomX Therapeutics, Inc.
    Inventors: Herman Waldmann, Mark Raymond Frewin, Lisa Kim Gilliland, Luis Richardo Simoes Da Silva Graca
  • Therapeutic Antibodies
    Publication number: 20170137529
    Abstract: A pharmaceutical comprising a therapeutic protein that binds to a therapeutic target, the protein being modified with a compound that inhibits binding of the protein to the therapeutic target, the modified protein being effective for reducing an immune response against the protein and for producing a therapeutic effect by binding to the therapeutic target. The therapeutic protein may be an antibody that includes an antibody combining site that binds to the therapeutic target.
    Type: Application
    Filed: December 18, 2015
    Publication date: May 18, 2017
    Inventors: Herman Waldmann, Mark Raymond Frewin, Lisa Kim Gilliland, Luis Richardo Simoes Da Silva Graca
  • Therapeutic Antibodies
    Publication number: 20140212418
    Abstract: A pharmaceutical comprising a therapeutic protein that hinds to a therapeutic target, the protein being modified with a compound that inhibits binding of the protein to the therapeutic target, the modified protein being effective for reducing an immune response against the protein and for producing a therapeutic effect by binding to the therapeutic target. The therapeutic protein may be an antibody that includes an antibody combining site that binds to the therapeutic target.
    Type: Application
    Filed: July 31, 2013
    Publication date: July 31, 2014
    Inventors: Herman Waldmann, Mark Raymond Frewin, Lisa Kim Gilliland, Luis Richardo Simoes Da Silva Graca
  • Therapeutic antibodies
    Patent number: 8623357
    Abstract: A pharmaceutical comprising a therapeutic protein that hinds to a therapeutic target, the protein being modified with a compound that inhibits binding of the protein to the therapeutic target, the modified protein being effective for reducing an immune response against the protein and for producing a therapeutic effect by binding to the therapeutic target. The therapeutic protein may be an antibody that includes an antibody combining site that binds to the therapeutic target.
    Type: Grant
    Filed: December 15, 2008
    Date of Patent: January 7, 2014
    Assignee: Isis Innovation, Ltd.
    Inventors: Hermann Waldmann, Mark Raymond Frewin, Lisa Kim Gilliland, Luis Richardo Simoes da Silva Graca
  • Therapeutic antibodies
    Publication number: 20100015166
    Abstract: A pharmaceutical comprising a therapeutic protein that hinds to a therapeutic target, the protein being modified with a compound that inhibits binding of the protein to the therapeutic target, the modified protein being effective for reducing an immune response against the protein and for producing a therapeutic effect by binding to the therapeutic target. The therapeutic protein may be an antibody that includes an antibody combining site that binds to the therapeutic target.
    Type: Application
    Filed: December 15, 2008
    Publication date: January 21, 2010
    Inventors: Herman Waldmann, Mark Raymond Frewin, Lisa Kim Gilliland, Luis Richardo Simoes da Silva Graca
  • Therapeutic antibodies
    Patent number: 7465790
    Abstract: A pharmaceutical comprising a therapeutic protein that binds to a therapeutic target, the protein being modified with a compound that inhibits binding of the protein to the therapeutic target, the modified protein being effective for reducing an immune response against the protein and for producing a therapeutic effect by binding to the therapeutic target. The therapeutic protein may be an antibody that includes an antibody combining site that binds to the therapeutic target.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: December 16, 2008
    Assignee: ISIS INNOVATION, Inc.
    Inventors: Herman Waldmann, Mark Raymond Frewin, Lisa Kim Gilliland, Luis Richardo Simoes da Silva Graca
  • Therapeutic antibodies
    Publication number: 20040258677
    Abstract: A pharmaceutical comprising a therapeutic protein that binds to a therapeutic target, the protein being modified with a compound that inhibits binding of the protein to the therapeutic target, the modified protein being effective for reducing an immune response against the protein and for producing a therapeutic effect by binding to the therapeutic target. The therapeutic protein may be an antibody that includes an antibody combining site that binds to the therapeutic target.
    Type: Application
    Filed: July 29, 2002
    Publication date: December 23, 2004
    Inventors: Herman Waldmann, Mark Raymond Frewin, Lisa Kim Gilliland, Luis Richardo Simoes da Silva Graca