Patents by Inventor Luke F. Vistain

Luke F. Vistain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MRI contrast agents
    Patent number: 9585975
    Abstract: The present invention relates to MRI based imaging. In particular, the present invention provides MRI contrast agents targeted to a HaloTag protein with tunable relaxation properties thereby providing optimal relaxivity for low field strength imaging and the other optimal relaxivity for high field strength imaging. Moreover, the MRI contrast agents are used to detect gene expression (of a gene of interest) in real time in vivo, to detect changes in gene expression (of a gene of interest) over time in, for example, an individual organism, to detect gene expression changes (of a gene of interest) in response to therapeutics, in cell labeling for MR imaging, in clinical diagnostics, and in theranostics.
    Type: Grant
    Filed: March 29, 2013
    Date of Patent: March 7, 2017
    Assignee: Northwestern University
    Inventors: Thomas J. Meade, Renee C. Strauch, Luke F. Vistain
  • MRI CONTRAST AGENTS
    Publication number: 20130302258
    Abstract: The present invention relates to MRI based imaging. In particular, the present invention provides MRI contrast agents targeted to a HaloTag protein with tunable relaxation properties thereby providing optimal relaxivity for low field strength imaging and the other optimal relaxivity for high field strength imaging. Moreover, the MRI contrast agents are used to detect gene expression (of a gene of interest) in real time in vivo, to detect changes in gene expression (of a gene of interest) over time in, for example, an individual organism, to detect gene expression changes (of a gene of interest) in response to therapeutics, in cell labeling for MR imaging, in clinical diagnostics, and in theranostics.
    Type: Application
    Filed: March 29, 2013
    Publication date: November 14, 2013
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Thomas J. Meade, Renee C. Strauch, Luke F. Vistain