Patents by Inventor Lun H. Lam

Lun H. Lam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sulfated polysaccharides as inhibitors of smooth muscle cell proliferation
    Patent number: 5380716
    Abstract: Highly sulfated oligosaccharides in the form of hexasaccharide and octasaccharide compounds which have antiproliferative activity with respect to smooth muscle cells are useful in treatment of conditions characterized by unwanted smooth muscle cell proliferation such as a result of trauma or disease states such as asthma, congestive heart failure and hypertension. The oligosaccharides have increased ability to inhibit the proliferation of smooth muscle cells and decreased ability to act as an anticoagulant as compared with commercial heparin and/or unseparated fragments of heparin.
    Type: Grant
    Filed: December 28, 1992
    Date of Patent: January 10, 1995
    Assignee: Glycomed, Inc.
    Inventors: H. Edward Conrad, Peter Fugedi, Brian K. Brandley, Lun H. Lam, Roger A. Laine
  • Method for separation of anionic oligosaccharides
    Patent number: 5145956
    Abstract: Separation of anionic oligosaccharides on a preparative scale with high resolution can be achieved by anionic exchange chromatography using PEI-derivatized supports.
    Type: Grant
    Filed: December 11, 1991
    Date of Patent: September 8, 1992
    Assignee: Glycomed Incorporated
    Inventors: Lun H. Lam, David Tyrrell
  • Heparin fragments as inhibitors of smooth muscle cell proliferation
    Patent number: 5032679
    Abstract: A glycosaminoglycoside (GAG) composition predominantly of tetrasacchardie units derived from heparin/heparan sulfate has enchanced activity in preventing the proliferation of smooth muscle cells. This GAG preparation is useful in the treatment of diseases characterized by unwanted smooth muscle cell proliferation and activity.
    Type: Grant
    Filed: August 31, 1989
    Date of Patent: July 16, 1991
    Assignee: Glycomed, Inc.
    Inventors: Brian K. Brandley, Lun H. Lam, Roger A. Laine