Patents by Inventor Lynn Margaret Bjerke

Lynn Margaret Bjerke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CDK9 as modifier of the IGF pathway and methods of use
    Patent number: 8758994
    Abstract: Human CDK9 genes are identified as modulators of the IGF pathway, and thus are therapeutic targets for disorders associated with defective IGF function. Methods for identifying modulators of IGF, comprising screening for agents that modulate the activity of CDK9 are provided.
    Type: Grant
    Filed: June 20, 2005
    Date of Patent: June 24, 2014
    Assignee: Exelixis, Inc.
    Inventors: Mark E. Maxwell, Michael Martin Ollmann, Timothy S. Heuer, Lynn Margaret Bjerke
  • EEF2K as modifiers of the PTEN/AKT pathway and methods of use
    Patent number: 8679763
    Abstract: Human EEF2K genes are identified as modulators of the PTEN/AKT pathway and thus are therapeutic targets for disorders associated with defective PTEN/AKT function. Methods for identifying modulators of PTEN/AKT comprising screening for agents that modulate the activity of EEF2K are provided.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: March 25, 2014
    Assignee: Exelixis, Inc.
    Inventors: Arthur Brace, Robert A. Blake, Lori S. Friedman, Lynn Margaret Bjerke, Kevin M. Ward, Susana Nieto-Bergman
  • PLKS as modifiers of the beta catenin pathway and methods of use
    Patent number: 8632962
    Abstract: Human PLK genes are identified as modulators of the beta catenin pathway, and thus are therapeutic targets for disorders associated with defective beta catenin function. Methods for identifying modulators of beta catenin, comprising screening for agents that modulate the activity of PLK are provided.
    Type: Grant
    Filed: November 23, 2004
    Date of Patent: January 21, 2014
    Assignee: Exelixis, Inc.
    Inventors: Helen Francis-Lang, Christopher G. Winter, Richard Benn Abegania Ventura, Lynn Margaret Bjerke, Timothy S. Heuer
  • PIK4CA as modifier of the Rac pathway and methods of use
    Patent number: 8481269
    Abstract: Human PIK4CA genes are identified as modulators of the RAC pathway, and thus are therapeutic targets for disorders associated with defective RAC function. Methods for identifying modulators of RAC, comprising screening for agents that modulate the activity of PIK4CA are provided.
    Type: Grant
    Filed: September 15, 2005
    Date of Patent: July 9, 2013
    Assignee: Exelixis, Inc.
    Inventors: Lisa C. Kadyk, George Ross Francis, Lynn Margaret Bjerke, Timothy S. Heuer
  • PGDS as modifiers of the PTEN pathway and methods of use
    Patent number: 8288119
    Abstract: Human PGD genes are identified as modulators of the PTEN pathway, and thus are therapeutic targets for disorders associated with defective PTEN function. Methods for identifying modulators of PTEN, comprising screening for agents that modulate the activity of PGD are provided.
    Type: Grant
    Filed: June 20, 2005
    Date of Patent: October 16, 2012
    Assignee: Exelixis, Inc.
    Inventors: Chunyan Song, Michael Martin Ollmann, Lynn Margaret Bjerke
  • Mylks as modifiers of branching morphogenesis and methods of use
    Patent number: 8105785
    Abstract: Human MYLK genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of MYLK are provided.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: January 31, 2012
    Assignee: Exelixis, Inc.
    Inventors: Gregory D. Plowman, Felix D. Karim, Candace Swimmer, Hinrich Alexander Habeck, Thomas I. Koblizek, Stefan Schulte-Merker, Ulrike Eisenmann, Gordon Mark Stott, Torsten Trowe, Andreas Michael Vogel, Joerg Heinrich Odenthal, Jochen Konrad Scheel, Torsten Tilmann Will, Yinsheng Jin, Lynn Margaret Bjerke, Timothy S. Heuer
  • C20ORF23 as modifier of the IGFR pathway and methods of use
    Patent number: 7943302
    Abstract: Human C20ORF23 genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of C20ORF23 are provided.
    Type: Grant
    Filed: March 10, 2005
    Date of Patent: May 17, 2011
    Assignee: Exelixis, Inc.
    Inventors: Lori Friedman, Helen Francis-Lang, Annette L. Parks, Kenneth James Shaw, Lynn Margaret Bjerke, Timothy S. Heuer
  • KIFS as Modifiers of the RHO Pathway and Methods of Use
    Publication number: 20110111402
    Abstract: Human KIF23 genes are identified as modulators of the RHO pathway, and thus are therapeutic targets for disorders associated with defective RHO function. Methods for identifying modulators of RHO, comprising screening for agents that modulate the activity of KIF23 are provided.
    Type: Application
    Filed: September 24, 2010
    Publication date: May 12, 2011
    Applicant: EXELIXIS INC.
    Inventors: Joanne ADAMKEWICZ, Craig D. AMUNDSEN, Lynn Margaret BJERKE, George Ross FRANCIS, Timothy S. HEUER, Kim LICKTEIG, Monique NICOLL
  • P4HAS as modifiers of the IGFR pathway and methods of use
    Patent number: 7888048
    Abstract: Human P4HA genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of P4HA are provided.
    Type: Grant
    Filed: June 20, 2005
    Date of Patent: February 15, 2011
    Assignee: Exelixis, Inc.
    Inventors: Lori S. Friedman, Helen Francis-Lang, Annette L. Parks, Kenneth James Shaw, Timothy S. Heuer, Lynn Margaret Bjerke
  • PDEs as modifiers of the IGFR pathways and methods of use
    Patent number: 7888047
    Abstract: Human PDE genes are identified as modulators of the IGFR pathway and thus are therapeutic targets for disorders associated with defective IGFR function Methods for identifying modulators of IGFR comprising screening for agents that modulate the activity of PDE are provided.
    Type: Grant
    Filed: March 10, 2005
    Date of Patent: February 15, 2011
    Assignee: Exelixis, Inc.
    Inventors: Lori Friedman, Helen Francis-Lang, Annette L. Parks, Kenneth James Shaw, Lynn Margaret Bjerke, Timothy S. Heuer
  • CSNKS As Modifiers of the RAC Pathway and Methods of Use
    Publication number: 20110033853
    Abstract: Human CSNK genes are identified as modulators of the RAC pathway, and thus are therapeutic targets for disorders associated with defective RAC function. Methods for identifying modulators of RAC, comprising screening for agents that modulate the activity of CSNK are provided.
    Type: Application
    Filed: May 5, 2010
    Publication date: February 10, 2011
    Applicant: EXELIXIS, INC.
    Inventors: LISA C. KADYK, GEORGE ROSS FRANCIS, LYNN MARGARET BJERKE
  • C20ORF23 as modifier of the IGFR pathway and methods of use
    Publication number: 20090202563
    Abstract: Human C20ORF23 genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of C20ORF23 are provided.
    Type: Application
    Filed: March 10, 2005
    Publication date: August 13, 2009
    Applicant: EXELIXIS, INC.
    Inventors: Lori Friedman, Helen Francis-Lang, Annette L. Parks, Kenneth James Shaw, Lynn Margaret Bjerke, Timothy S. Heuer
  • Pfks as modifiers of the igfr pathway and methods of use
    Publication number: 20090142272
    Abstract: Human PFK genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of PFK are provided.
    Type: Application
    Filed: June 20, 2005
    Publication date: June 4, 2009
    Applicant: Exelixis, Inc.
    Inventors: Lori S. Friedman, Helen Francis-Lang, Annette L. Parks, Kenneth James Shaw, Lynn Margaret Bjerke, Timothy S. Heuer
  • ACACS As Modifiers of the IGF Pathway and Methods of Use
    Publication number: 20090053239
    Abstract: Human MPTEN genes are identified as modulators of the PTEN pathway, and thus are therapeutic targets for disorders associated with defective PTEN function. Methods for identifying modulators of PTEN, comprising screening for agents that modulate the activity of MPTEN are provided.
    Type: Application
    Filed: June 20, 2005
    Publication date: February 26, 2009
    Applicant: EXELIXIS, INC.
    Inventors: Mark E. Maxwell, Michael Martin Ollmann, Timothy S. Heuer, Lynn Margaret Bjerke
  • GALNTS AS MODIFIERS OF THE IGFR PATHWAY AND METHODS OF USE
    Publication number: 20090028844
    Abstract: Human MIGFR genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of MIGFR are provided.
    Type: Application
    Filed: June 20, 2005
    Publication date: January 29, 2009
    Applicant: EXELIXIS, INC.
    Inventors: Lori S. Friedman, Helen Francis-Lang, Annette L. Parks, Kenneth James Shaw, Timothy S. Heuer, Lynn Margaret Bjerke
  • P4HAS AS MODIFIERS OF THE IGFR PATHWAY AND METHODS OF USE
    Publication number: 20090025096
    Abstract: Human P4HA genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of P4HA are provided.
    Type: Application
    Filed: June 20, 2005
    Publication date: January 22, 2009
    Applicant: EXELIXIS, INC.
    Inventors: Lori S. Friedman, Helen Francis-Lang, Annette L. Parks, Kenneth James Shaw, Timothy S. Heuer, Lynn Margaret Bjerke
  • PGDS AS MODIFIERS OF THE PTEN PATHWAY AND METHODS OF USE
    Publication number: 20090019558
    Abstract: Human PGD genes are identified as modulators of the PTEN pathway, and thus are therapeutic targets for disorders associated with defective PTEN function. Methods for identifying modulators of PTEN, comprising screening for agents that modulate the activity of PGD are provided.
    Type: Application
    Filed: June 20, 2005
    Publication date: January 15, 2009
    Applicant: EXELIXIS, INC.
    Inventors: Chunyan Song, Michael Martin Ollmann, Lynn Margaret Bjerke
  • PDES AS MODIFIERS OF THE IGFR PATHWAYS AND METHODS OF USE
    Publication number: 20090013416
    Abstract: Human PDE genes are identified as modulators of the IGFR pathway and thus are therapeutic targets for disorders associated with defective IGFR function Methods for identifying modulators of IGFR comprising screening for agents that modulate the activity of PDE are provided
    Type: Application
    Filed: March 10, 2005
    Publication date: January 8, 2009
    Applicant: EXELIXIS, INC.
    Inventors: Lori Friedman, Helen Francis-Lang, Annette L. Parks, Kenneth James Shaw, Lynn Margaret Bjerke, Timothy S. Heuer
  • Kifs as Modifiers of the Rho Pathway and Methods of Use
    Publication number: 20090004180
    Abstract: Human KIF23 genes are identified as modulators of the RHO pathway, and thus are therapeutic targets for disorders associated with defective RHO function. Methods for identifying modulators of RHO, comprising screening for agents that modulate the activity of KIF23 are provided.
    Type: Application
    Filed: November 9, 2006
    Publication date: January 1, 2009
    Applicant: Exelixis Inc.
    Inventors: Joanne Adamkewicz, Craig D. Amundsen, Lynn Margaret Bjerke, George Ross Francis, Timothy S. Heuer, Kim Lickteig, Monique Nicoll
  • Mylks as Modifiers of Branching Morphogenesis and Methods of Use
    Publication number: 20080317738
    Abstract: Human MYLK genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of MYLK are provided.
    Type: Application
    Filed: June 18, 2004
    Publication date: December 25, 2008
    Applicant: Exelixis, Inc.
    Inventors: Gregory D. Plowman, Felix D. Karim, Candace Swimmer, Hinrich Alexander Habeck, Thomas I. Koblizek, Stefan Schulte-Merker, Ulrike Eisenmann, Gordon Mark Stott, Torsten Trowe, Andreas Michael Vogel, Joerg Heinrich Odenthal, Jochen Konrad Scheel, Torsten Tilmann Will, Yinsheng Jin, Lynn Margaret Bjerke, Timothy S. Heuer