Patents by Inventor Lynn N. Truong

Lynn N. Truong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIMERIC ANTIGEN RECEPTOR MEDIATED CELL TARGETING
    Publication number: 20190048060
    Abstract: Disclosed herein are methods and compositions for engineering cells to express a CAR where the cells also have inactivated TCR, HPRT, PD1, CISH and/or HLA genes, using engineered nucleases comprising at least one DNA binding domain and a cleavage domain or cleavage half-domain in conditions able to preserve cell viability. Polynucleotides encoding nucleases, vectors comprising polynucleotides encoding nucleases and cells comprising polynucleotides encoding nucleases and/or cells comprising nucleases are also provided.
    Type: Application
    Filed: August 8, 2018
    Publication date: February 14, 2019
    Inventors: Anthony Conway, Sumiti Jain, Gary K. Lee, Andreas Reik, Lynn N. Truong