Patents by Inventor Lyubka Kirilova

Lyubka Kirilova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of Taq polymerase mutant enzymes for nucleic acid amplification in the presence of PCR inhibitors
    Patent number: 9796965
    Abstract: The present invention generally relates to detection of a target nucleic acid in standard PCR, real-time PCR, RT PCR, and real-time RT PCR. One aspect of the invention provides mutant DNA polymerase enzymes that are resistant to PCR inhibitors, such as dye, blood, and soil. Another aspect of the invention provides for methods of real-time PCR assays using mutant DNA polymerase enzymes resistant to PCR inhibitors with samples containing dye, blood, and/or soil. Another aspect of the invention provides for methods of standard PCR assays using mutant DNA polymerase enzymes resistant to PCR inhibitors with samples containing blood and/or soil.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: October 24, 2017
    Assignee: DNA Polymerase Technology, Inc.
    Inventors: Milko Kermekchiev, Lyubka Kirilova, Zhian Zhang
  • USE OF TAQ POLYMERASE MUTANT ENZYMES FOR NUCLEIC ACID AMPLIFICATION IN THE PRESENCE OF PCR INHIBITORS
    Publication number: 20150368624
    Abstract: The present invention generally relates to detection of a target nucleic acid in standard PCR, real-time PCR, RT PCR, and real-time RT PCR. One aspect of the invention provides mutant DNA polymerase enzymes that are resistant to PCR inhibitors, such as dye, blood, and soil. Another aspect of the invention provides for methods of real-time PCR assays using mutant DNA polymerase enzymes resistant to PCR inhibitors with samples containing dye, blood, and/or soil. Another aspect of the invention provides for methods of standard PCR assays using mutant DNA polymerase enzymes resistant to PCR inhibitors with samples containing blood and/or soil.
    Type: Application
    Filed: June 23, 2015
    Publication date: December 24, 2015
    Inventors: Milko Kermekchiev, Lyubka Kirilova, Zhian Zhang
  • USE OF TAQ POLYMERASE MUTANT ENZYMES FOR NUCLEIC ACID AMPLIFICATION IN THE PRESENCE OF PCR INHIBITORS
    Publication number: 20110027832
    Abstract: The present invention generally relates to detection of a target nucleic acid in standard PCR, real-time PCR, RT PCR, and real-time RT PCR. One aspect of the invention provides mutant DNA polymerase enzymes that are resistant to PCR inhibitors, such as dye, blood, and soil. Another aspect of the invention provides for methods of real-time PCR assays using mutant DNA polymerase enzymes resistant to PCR inhibitors with samples containing dye, blood, and/or soil. Another aspect of the invention provides for methods of standard PCR assays using mutant DNA polymerase enzymes resistant to PCR inhibitors with samples containing blood and/or soil.
    Type: Application
    Filed: March 16, 2009
    Publication date: February 3, 2011
    Applicant: DNA POLYMERASE TECHNOLOGY INC.
    Inventors: Milko B. Kermekchiev, Lyubka Kirilova, Zhian Zhang