Patents by Inventor M. Michele Manos

M. Michele Manos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection of human papillomavirus by the polymerase chain reaction using specific L1, and E6 probes
    Patent number: 5705627
    Abstract: The presence of human papillomavirus (HPV) in a sample can be detected and the HPV typed by a method that involves the amplification of HPV DNA sequences by the polymerase chain reaction (PCR). The primers used in the method are consensus primers that can be used to amplify a particular region of the genome of any HPV. The presence of HPV in a sample is indicated by the formation of amplified DNA. The HPV nucleic acid is detected by consensus probes that may be short oligonucleotide probes or long generic probes. The HPV is typed by the use of type-specific DNA probes specific for the amplified region of DNA.
    Type: Grant
    Filed: May 26, 1995
    Date of Patent: January 6, 1998
    Assignee: Roche Molecular Systems, Inc.
    Inventors: M. Michele Manos, Heidi M. Bauer, Catherine E. Greer, Robert M. Resnick, Yi Ting
  • Detection of human papillomavirus by the polymerase chain reaction
    Patent number: 5639871
    Abstract: The presence of human papillomavirus (HPV) in a sample can be detected and the HPV typed by a method that involves the amplification of HPV DNA sequences by the polymerase chain reaction (PCR). The primers used in the method are consensus primers that can be used to amplify a particular region of the genome of any HPV. The presence of HPV in a sample is indicated by the formation of amplified DNA. The HPV nucleic acid is detected by consensus probes that may be short oligonucleotide probes or long generic probes. The HPV is typed by the use of type-specific DNA probes specific for the amplified region of DNA.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: June 17, 1997
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Heidi M. Bauer, Patti E. Gravitt, Catherine E. Greer, Chaka C. Impraim, M. Michele Manos, Robert M. Resnick, Tracy Yi Zhang
  • Detection of human papillomavirus by the polymerase chain reaction
    Patent number: 5527898
    Abstract: The presence of human papillomavirus (HPV) in a sample can be detected and the HPV typed by a method that involves the amplification of HPV DNA sequences by the polymerase chain reaction (PCR). The primers used in the method are consensus primers that can be used to amplify a particular region of the genome of any HPV. The presence of HPV in a sample is indicated by the formation of amplified DNA. The HPV nucleic acid is detected by consensus probes that may be short oligonucleotide probes or long generic probes. The HPV is typed by the use of type-specific DNA probes specific for the amplified region of DNA.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 18, 1996
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Heidi M. Bauer, Patti E. Gravitt, Catherine E. Greer, M. Michele Manos, Robert M. Resnick, Tracy Y. Zhang
  • Detection of human papillomavirus by the polymerase chain reaction
    Patent number: 5447839
    Abstract: The presence of human papillomavirus (HPV) in a sample can be detected and the HPV typed by a method that involves the amplification of HPV DNA sequences by the polymerase chain reaction (PCR). The primers used in the method are consensus primers that can be used to amplify a particular region of the genome of any HPV. The presence of HPV in a sample is indicated by the formation of amplified DNA. The HPV nucleic acid is detected by consensus probes that may be short oligonucleotide probes or long genetic probes. The HPV is typed by the use of type-specific DNA probes specific for the amplified region of DNA.
    Type: Grant
    Filed: April 20, 1993
    Date of Patent: September 5, 1995
    Assignee: Hoffmann-La Roche Inc.
    Inventors: M. Michele Manos, Heidi M. Bauer, Catherine E. Greer, Robert M. Resnick, Yi Ting
  • Compositions for and detection of human papillomavirus by specific oligonucleotide polymerase primers using the polymerase chain reaction
    Patent number: 5283171
    Abstract: The presence of human papillomavirus (HPV) in a sample can be detected and the HPV typed by a method that involves the amplification of HPV DNA sequences by the polymerase chain reaction (PCR). The primers used in the method are consensus primers that can be used to amplify a particular region of the genome of any HPV. The presence of HPV in a sample is indicated by the formation of amplified DNA. The HPV is typed by the use of type-specific DNA probes specific for the amplified region of DNA.
    Type: Grant
    Filed: February 15, 1991
    Date of Patent: February 1, 1994
    Assignees: Hoffmann-La Roche Inc., The University of Rochester, New York
    Inventors: M. Michele Manos, Deann K. Wright, Yi Ting, Thomas R. Broker, Steven M. Wolinsky
  • Probes for detection of human papillomavirus
    Patent number: 5182377
    Abstract: The presence of human papillomavirus (HPV) in a sample can be detected and the HPV typed by a method that involves the amplification of HPV DNA sequences by the polymerase chain reaction (PCR). The primers used in the method are consensus primers that can be used to amplify a particular region of the genome of any HPV. The presence of HPV in a sample is indicated by the formation of amplified DNA. The HPV is typed by the use of type-specific DNA probes specific for the amplified region of DNA.
    Type: Grant
    Filed: March 10, 1989
    Date of Patent: January 26, 1993
    Assignee: Hoffmann-La Roche Inc.
    Inventors: M. Michele Manos, Deann K. Wright, Yi Ting