Abstract: A holder and disposal device for hypodermic needles safely detaches a needle from a syringe, permits use of multiple needles in sequence, and allows for the re-capping of needles without accidental puncture. The device includes a container having an interior space configured for receiving needles and needle covers. A top edge of the container defines an opening into the interior space. A lid is couplable to the container and is positionable in a closed position to cover the opening and in an open position to expose the opening. A gap is positioned in the lid. A clamp is couplable to the lid proximate the gap wherein pivoting the clamp opens and closes a pair of jaws above the gap such that the needles and needle covers positioned over the needles extend through the gap when the jaws are clamped onto the needle cover.