Patents by Inventor Maan Zrein

Maan Zrein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOMARKER ANTIBODY AND DIAGNOSIS DEVICE FOR DETECTING CERTAIN AUTOIMMUNE DISEASES
    Publication number: 20120128680
    Abstract: Antibodies which specifically bind to a peptide having the sequence Ala-Ala-Ala-Pro-Ala-Lys-Ala-Ala-Ala-Ala-Pro-Ala-Lys-Thr-Ala-Ala-Ala-Pro-Val (SEQ ID No1), and which are not induced in a host following an infection of the host with T. cruzi.
    Type: Application
    Filed: May 6, 2010
    Publication date: May 24, 2012
    Applicants: INFYNITY BIOMARKERS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON I, HOSPICES CIVILS DE LYON
    Inventors: Maan Zrein, Philippe Vanhems
  • Immunodiagnostic assays using reducing agents
    Patent number: 7935490
    Abstract: The present invention relates to a solid phase immunoassay comprising on said solid phase an antigen in the presence of a reducing agent.
    Type: Grant
    Filed: August 2, 2006
    Date of Patent: May 3, 2011
    Assignee: N.V. Innogenetics
    Inventors: Geert Maertens, Joost Louwagie, Alfons Bosman, Erwin Sablon, Maan Zrein
  • Immunodiagnostic assays using reducing agents
    Publication number: 20060263854
    Abstract: The present invention relates to a solid phase immunoassay comprising on said solid phase an antigen in the presence of a reducing agent.
    Type: Application
    Filed: August 2, 2006
    Publication date: November 23, 2006
    Applicant: N.V. INNOGENETICS
    Inventors: Geert Maertens, Joost Louwagie, Alfons Bosman, Erwin Sablon, Maan Zrein
  • Antigens and immunoassays for diagnosing Chagas' disease
    Publication number: 20030108960
    Abstract: Transfusion of contaminated blood has become the major route of transmission for Chagas' disease. Current screening tests are insensitive and yield conflicting results, while confirmatory assays do not exist. The present invention relates to antigens and their use for serological diagnosis of Chagas' disease. More specifically, the present invention concerns assays which are able to reliably and accurately detect the presence of antibodies to various specific antigens of Trypanosoma cruzi in a highly sensitive and specific manner.
    Type: Application
    Filed: July 16, 2002
    Publication date: June 12, 2003
    Applicant: INNOGENETICS N.V.
    Inventor: Maan Zrein
  • Antigens and immunoassays for diagnosing Chagas' disease
    Patent number: 6458922
    Abstract: Transfusion of contaminated blood has become the major route of transmission for Chagas' disease. Current screening tests are insensitive and yield conflicting results, while confirmatory assays do not exist. The present invention relates to antigens and their use for serological diagnosis of Chagas' disease. More specifically, the present invention concerns assays which are able to reliably and accurately detect the presence of antibodies to various specific antigens of Trypanosoma cruzi in a highly sensitive and specific manner.
    Type: Grant
    Filed: July 16, 1999
    Date of Patent: October 1, 2002
    Assignee: Innogenetics N.V.
    Inventor: Maan Zrein
  • Peptides, analogues and mixtures thereof for detecting and eliciting antibodies to the E1 and E2 protein of rubella virus
    Patent number: 5427792
    Abstract: This invention discloses linear and cyclic peptides of the E1 and E2 glycoproteins of the rubella virus. These peptides and analogues, mixtures and combinations of them are useful in detecting and quantifying antibodies raised against the rubella virus. They are also useful in raising antibodies to the rubella virus for use in the diagnosis of and protection against rubella viral infections.
    Type: Grant
    Filed: August 7, 1992
    Date of Patent: June 27, 1995
    Assignee: BioChem Immunosystems, Inc.
    Inventors: Maan Zrein, Martial Lacroix
  • Peptides and analogues and mixtures thereof for detecting antibodies to HTLV-I and HTLV-II viruses
    Patent number: 5359029
    Abstract: This invention relates to novel linear peptides and mixtures and chemical combinations thereof useful for detecting and quantifying HTLV-I and HTLV-II infections. These peptides are also useful in vaccines against HTLV-I and HTLV-II vital infections.
    Type: Grant
    Filed: March 20, 1991
    Date of Patent: October 25, 1994
    Assignee: Biochem Immunosystems Inc.
    Inventors: Martial Lacroix, Maan Zrein
  • Peptides and analogues and mixtures thereof for detecting and eliciting antibodies to rubella virus
    Patent number: 5298596
    Abstract: Linear and cyclic peptides of the E1 and C protein of the rubella virus are disclosed. These peptides and analogues, are useful in detecting and quantifying antibodies raised against the rubella virus. They are also useful in raising antibodies to the rubella virus for use in the diagnosis of and protection against rubella viral infections.
    Type: Grant
    Filed: March 13, 1992
    Date of Patent: March 29, 1994
    Assignee: Biochem Immunosystems Inc.
    Inventors: Martial Lacroix, Maan Zrein, Gervais Dionne
  • Peptides and analogues and mixtures thereof for detecting and eliciting antibodies to rubella virus
    Patent number: 5164481
    Abstract: Linear and cyclic peptides of the E1 and C protein of the rubella virus are disclosed. These peptides and analogues, mixtures and combinations of them are useful in detecting and quantifying antibodies raised against the rubella virus. They are also useful in raising antibodies to the rubella virus for use in the diagnosis of and protection against rubella viral infections.
    Type: Grant
    Filed: August 23, 1989
    Date of Patent: November 17, 1992
    Assignee: IAF Biochem International Inc.
    Inventors: Martial Lacroix, Maan Zrein, Gervais Dionne