Patents by Inventor Maarten Matthijs Sharif Van Lohuizen

Maarten Matthijs Sharif Van Lohuizen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EZH2- FGFR INHIBITION IN CANCER
    Publication number: 20220023293
    Abstract: The invention relates to a combination of a FGFR inhibitor and an EZH2 inhibitor for use in a method of treating a patient suffering from a BRCA1-associated protein 1 (BAP1) negative cancer. The invention further relates to a pharmaceutical preparation, comprising a FGFR inhibitor and an EZH2 inhibitor, to the use of said pharmaceutical preparation in a method of treating BAP1-negative cancer, to methods of identifying a patient with cancer, who is eligible for treatment with a combination of a FGFR inhibitor and an EZH2 inhibitor, and to a mouse model for mesothelioma.
    Type: Application
    Filed: December 3, 2019
    Publication date: January 27, 2022
    Inventors: Antonius Jozef Maria BERNS, Jitendra BADHAI, Maarten Matthijs Sharif VAN LOHUIZEN
  • Use of genes identified to be involved in tumor development for the development of anti-cancer drugs
    Publication number: 20040033974
    Abstract: The invention relates to the use of inhibitors of the expressed proteins of the murine genes and/or their human homologues listed in Table 1 for the preparation of a therapeutical composition for the treatment of cancer, in particular for the treatment of solid tumors of lung, colon, breast, prostate, ovarian, pancreas and leukemia. The invention also relates to the therapeutical compositions comprising the inhibitors and to methods for development of the inhibitor compounds.
    Type: Application
    Filed: August 19, 2002
    Publication date: February 19, 2004
    Applicant: Kylix B.V.
    Inventors: Anders Henrik Lund, Antonius Jozef Maria Berns, Maarten Matthijs Sharif Van Lohuizen, Carla Pedro Martins, Henricus Martinus Maria Mikkers, Jack Richard Lenz