Patents by Inventor Madhu Ayyagari

Madhu Ayyagari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240066181
    Abstract: A viscoelastic composition is disclosed which comprises (a) tris(hydroxymethyl)aminomethane or a salt thereof; (b) a phosphate buffer agent; and (c) a viscoelastic agent having an average molecular weight of about 100 to about 5,000,000.
    Type: Application
    Filed: October 10, 2023
    Publication date: February 29, 2024
    Inventors: Kimberly Anne Millard, Madhu Ayyagari, Erning Xia, Bill Reindel
  • Publication number: 20190151500
    Abstract: A viscoelastic composition is disclosed which comprises (a) tris(hydroxymethyl)aminomethane or a salt thereof; (b) a phosphate buffer agent; and (c) a viscoelastic agent having an average molecular weight of about 100 to about 5,000,000.
    Type: Application
    Filed: November 16, 2018
    Publication date: May 23, 2019
    Inventors: Kimberly Anne Millard, Madhu Ayyagari, Erning Xia, Bill Reindel
  • Patent number: 9155615
    Abstract: An intraocular lens (“IOL”) cartridge includes an upper wall and a lower wall, together defining a lumen for receiving an IOL. The proximal end of the cartridge has an open slot cut into and through the entire thickness of the upper wall so to allow the leading haptic of the IOL to extend above the upper wall. The cartridge includes a proximal-end feature to facilitate folding of the leading haptic radially inward relative to the optic as the IOL moves into the lumen.
    Type: Grant
    Filed: November 9, 2012
    Date of Patent: October 13, 2015
    Assignee: Bausch & Lomb Incorporated
    Inventors: Moises Valle, Nathan Belcher, Sushant Muchhala, Will Seo, Madhu Ayyagari
  • Publication number: 20140135782
    Abstract: An IOL injector cartridge, comprising an upper wall, a lower wall, the upper wall and the lower wall combining to define a lumen that extends from a proximal end to a distal end, a slot extending through the entire thickness of the upper wall and extending from the proximal end and having a slot distal end formed by the upper wall, an edge of the upper wall that, at least partially defines the slot, having a convex curvature, the curvature occurring along the thickness of the edge.
    Type: Application
    Filed: November 9, 2012
    Publication date: May 15, 2014
    Applicant: Bausch & Lomb Incorporated
    Inventors: Moises Valle, Nathan Belcher, Sushant Muchhala, Will Seo, Madhu Ayyagari
  • Publication number: 20070052923
    Abstract: A method for limiting a transfer of an additive in a first polymeric article to a second adjacent polymeric article comprises treating at least a portion of the first article under a condition such that the additive is transformed to a substantially stable phase. A polymeric article comprises a compounded polymeric material that comprises an additive in a base polymeric material, wherein the additive exists in a substantially stable phase.
    Type: Application
    Filed: September 6, 2005
    Publication date: March 8, 2007
    Inventors: Madhu Ayyagari, David Vanderbilt, George Diaz, Christopher Wagner
  • Patent number: 7022813
    Abstract: A process for treating biomedical devices, especially contact lenses, involves contacting polymeric devices containing extractables with a solvent that dissolves and thereby removes the extractables from the device, treating the solvent to remove extractables from the solvent, thereby purifying the solvent, and using the purified solvent to remove additional extractables from polymeric devices.
    Type: Grant
    Filed: May 13, 2002
    Date of Patent: April 4, 2006
    Assignee: Bausch & Lomb Incorporated
    Inventors: Madhu Ayyagari, Erik M. Indra, Mahendra P. Nandu
  • Patent number: 6998073
    Abstract: A method of extracting residual materials from a polymeric, ophthalmic biomedical device, such as a contact lens, by using a mixture comprised of a primary solvent, such as carbon dioxide, and a polar co-solvent, such as isopropanol. By exposing the device to the co-solvent, the device expands. By pulsing or varying the concentration of the polar co-solvent in the mixture, the lens dimensions vary accordingly. When the lens is extracted while retained in a mold, the changes in lens dimensions causes the lens to be released from the mold.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: February 14, 2006
    Assignee: Bausch & Lomb Incorporated
    Inventors: Madhu Ayyagari, Mahendra P. Nandu, Erik M. Indra, Alan J. Braun
  • Publication number: 20050285288
    Abstract: A method of extracting residual materials from a polymeric, ophthalmic biomedical device, such as a contact lens, by using a mixture comprised of a primary solvent, such as carbon dioxide, and a polar co-solvent, such as isopropanol: By exposing the device to the co-solvent, the device expands. By pulsing or varying the concentration of the polar co-solvent in the mixture, the lens dimensions vary accordingly. When the lens is extracted while retained in a mold, the changes in lens dimensions causes the lens to be released from the mold.
    Type: Application
    Filed: August 24, 2005
    Publication date: December 29, 2005
    Inventors: Madhu Ayyagari, Mahendra Nandu, Erik Indra, Alan Braun
  • Publication number: 20030222362
    Abstract: A process for treating biomedical devices, especially contact lenses, involves contacting polymeric devices containing extractables with a solvent that dissolves and removes the extractables from the devices. The devices are subjected to at least two treatments with fresh solvent to remove extractables in the devices.
    Type: Application
    Filed: March 19, 2003
    Publication date: December 4, 2003
    Applicant: Bausch & Lomb Incorporated
    Inventors: Erik M. Indra, Madhu Ayyagari, Mahendra P. Nandu
  • Patent number: 6634931
    Abstract: A process of dry polishing molded or lathe cut intraocular lenses to removing flash, sharp edges and/or surface irregularities therefrom. The process includes rotational tumbling of partially protected intraocular lenses in a dry polishing media. The process is suitable for single piece and multipiece intraocular lenses of varying composition.
    Type: Grant
    Filed: December 11, 2000
    Date of Patent: October 21, 2003
    Assignee: Bausch & Lomb Surgical, Inc.
    Inventors: Madhu Ayyagari, Mahendra P. Nandu
  • Patent number: 6612907
    Abstract: A process of dry polishing molded or lathe cut intraocular lenses or like medical devices to removing flash, sharp edges and/or surface irregularities therefrom. The process includes gas and/or rotational tumbling of the intraocular lenses or like medical devices in a dry polishing media. The process is suitable for single piece and multipiece intraocular lenses of varying composition.
    Type: Grant
    Filed: August 9, 2002
    Date of Patent: September 2, 2003
    Assignee: Bausch & Lomb Incorporated
    Inventors: Madhu Ayyagari, Mahendra P. Nandu
  • Publication number: 20030116873
    Abstract: A method of extracting residual materials from a polymeric, ophthalmic biomedical device, such as a contact lens, by using a mixture comprised of a primary solvent, such as carbon dioxide, and a polar co-solvent, such as isopropanol. By exposing the device to the co-solvent, the device expands. By pulsing or varying the concentration of the polar co-solvent in the mixture, the lens dimensions vary accordingly. When the lens is extracted while retained in a mold, the changes in lens dimensions causes the lens to be released from the mold.
    Type: Application
    Filed: December 17, 2002
    Publication date: June 26, 2003
    Applicant: Bausch & Lomb Incorporated
    Inventors: Madhu Ayyagari, Mahendra P. Nandu, Erik M. Indra, Alan J. Braun
  • Patent number: 6581761
    Abstract: A tray assembly for holding small devices such as polymeric ophthalmic lenses includes a mesh insert having a plurality of wells for containing individual lenses. The assembly may also include a support tray having a perimeter substantially conforming in shape to the outer edge of the mesh insert. Contact is maintained between the support tray and the mesh insert to confine the lenses within the assembly. A stack assembly includes a plurality of multiwell circular mesh trays and corresponding mesh tray covers stacked and secured on a center shaft and provides substantially enhanced efficiency and productivity in processes such as extraction or hydration. Additionally, portions of the mesh insert and support tray may be used with such processes such as lens coating and surface treatment.
    Type: Grant
    Filed: October 10, 2000
    Date of Patent: June 24, 2003
    Assignee: Bausch & Lomb Incorporated
    Inventors: Ulick Stafford, Larry C. Hovey, Madhu Ayyagari
  • Patent number: 6575814
    Abstract: A process of dry polishing molded or lathe cut intraocular lenses or like medical devices to removing flash, sharp edges and/or surface irregularities therefrom. The process includes gas and/or rotational tumbling of the intraocular lenses or like medical devices in a dry polishing media. The process is suitable for single piece and multipiece intraocular lenses of varying composition.
    Type: Grant
    Filed: August 21, 2000
    Date of Patent: June 10, 2003
    Assignee: Bausch & Lomb Incorporated
    Inventors: Madhu Ayyagari, Mahendra P. Nandu
  • Publication number: 20030054733
    Abstract: A process of dry polishing molded or lathe cut intraocular lenses or like medical devices to removing flash, sharp edges and/or surface irregularities therefrom. The process includes gas and/or rotational tumbling of the intraocular lenses or like medical devices in a dry polishing media. The process is suitable for single piece and multipiece intraocular lenses of varying composition.
    Type: Application
    Filed: August 9, 2002
    Publication date: March 20, 2003
    Inventors: Madhu Ayyagari, Mahendra P. Nandu
  • Patent number: 6514438
    Abstract: A method of extracting residual materials from a polymeric, ophthalmic biomedical device, such as a contact lens, by using a mixture comprised of a primary solvent, such as carbon dioxide, and a polar co-solvent, such as isopropanol. By exposing the device to the co-solvent, the device expands. By pulsing or varying the concentration of the polar co-solvent in the mixture, the lens dimensions vary accordingly. When the lens is extracted while retained in a mold, the changes in lens dimensions causes the lens to be released from the mold.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: February 4, 2003
    Assignee: Bausch & Lomb Incorporated
    Inventors: Madhu Ayyagari, Mahendra P. Nandu, Erik M. Indra, Alan J. Braun
  • Publication number: 20020193052
    Abstract: A process of dry polishing molded or lathe cut intraocular lenses or like medical devices to removing flash, sharp edges and/or surface irregularities therefrom. The process includes gas and/or rotational tumbling of the intraocular lenses or like medical devices in a dry polishing media. The process is suitable for single piece and multipiece intraocular lenses of varying composition.
    Type: Application
    Filed: August 9, 2002
    Publication date: December 19, 2002
    Inventors: Madhu Ayyagari, Mahendra P. Nandu
  • Publication number: 20020132971
    Abstract: A process for treating biomedical devices, especially contact lenses, involves contacting polymeric devices containing extractables with a solvent that dissolves and thereby removes the extractables from the device, treating the solvent to remove extractables from the solvent, thereby purifying the solvent, and using the purified solvent to remove additional extractables from polymeric devices.
    Type: Application
    Filed: May 13, 2002
    Publication date: September 19, 2002
    Inventors: Madhu Ayyagari, Erik M. Indra, Mahendra P. Nandu
  • Patent number: 6423820
    Abstract: A process for treating biomedical devices, especially contact lenses, involves contacting polymeric devices containing extractables with a solvent that dissolves and thereby removes the extractables from the device, treating the solvent to remove extractables from the solvent, thereby purifying the solvent, and using the purified solvent to remove additional extractables from polymeric devices.
    Type: Grant
    Filed: September 22, 2000
    Date of Patent: July 23, 2002
    Assignee: Bausch & Lomb Incorporated
    Inventors: Madhu Ayyagari, Erik M. Indra, Mahendra P. Nandu
  • Publication number: 20020072305
    Abstract: A process of dry polishing molded or lathe cut intraocular lenses to removing flash, sharp edges and/or surface irregularities therefrom. The process includes rotational tumbling of partially protected intraocular lenses in a dry polishing media. The process is suitable for single piece and multipiece intraocular lenses of varying composition.
    Type: Application
    Filed: December 11, 2000
    Publication date: June 13, 2002
    Inventors: Madhu Ayyagari, Mahendra P. Nandu