Patents by Inventor Mads Gurtler

Mads Gurtler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SERUM-FREE IN VITRO DIRECTED DIFFERENTIATION PROTOCOL FOR GENERATING STEM CELL-DERIVED BETA CELLS AND USES THEREOF
    Publication number: 20240158753
    Abstract: Disclosed herein are methods for generating SC-? cells using chemically defined, completely serum free media, and isolated populations of SC-? cells for use in various applications, such as cell therapy.
    Type: Application
    Filed: October 19, 2023
    Publication date: May 16, 2024
    Inventors: Douglas A. Melton, Mads Gurtler
  • SC-BETA CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME
    Publication number: 20240124847
    Abstract: Disclosed herein are methods, compositions, kits, and agents useful for inducing ? cell maturation, and isolated populations of SC-? cells for use in various applications, such as cell therapy.
    Type: Application
    Filed: December 22, 2023
    Publication date: April 18, 2024
    Inventors: Quinn P. Peterson, Felicia J. Pagliuca, Douglas A. Melton, Jeffrey Robert Millman, Michael Saris Segel, Mads Gurtler
  • SC-BETA CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME
    Publication number: 20240101963
    Abstract: Disclosed herein are methods, compositions, kits, and agents useful for inducing ? cell maturation, and isolated populations of SC-? cells for use in various applications, such as cell therapy.
    Type: Application
    Filed: August 7, 2023
    Publication date: March 28, 2024
    Inventors: Quinn P. Peterson, Felicia J. Pagliuca, Douglas A. Melton, Jeffrey Robert Millman, Michael Saris Segel, Mads Gurtler, Alireza Rezania, Benjamin Fryer
  • SC-beta cells and compositions and methods for generating the same
    Patent number: 11827905
    Abstract: Disclosed herein are methods, compositions, kits, and agents useful for inducing ? cell maturation, and isolated populations of SC-? cells for use in various applications, such as cell therapy.
    Type: Grant
    Filed: November 1, 2022
    Date of Patent: November 28, 2023
    Assignee: President and Fellows of Harvard College
    Inventors: Quinn P. Peterson, Felicia J. Pagliuca, Douglas A. Melton, Jeffrey Robert Millman, Michael Saris Segel, Mads Gurtler
  • METHODS OF ENHANCING STEM CELL DIFFERENTIATION INTO BETA CELLS
    Publication number: 20230146780
    Abstract: Disclosed herein are compositions and methods of enhancing stem cell differentiation into beta cells with use of one or more epigenetic modification compounds. The present disclosure also relates to compositions and methods of sorting and enriching the differentiated beta cells. The present disclosure also relates to compositions and methods of irradiating cell population for reducing proliferation.
    Type: Application
    Filed: November 11, 2022
    Publication date: May 11, 2023
    Inventors: Felicia PAGLIUCA, George HARB, Mads GURTLER, Austin THIEL, Jihad YASIN, Evrett THOMPSON
  • METHODS OF ENHANCING STEM CELL DIFFERENTIATION INTO BETA CELLS
    Publication number: 20230137854
    Abstract: Disclosed herein are compositions and methods of enhancing stem cell differentiation into beta cells with use of one or more epigenetic modification compounds. The present disclosure also relates to compositions and methods of sorting and enriching the differentiated beta cells. The present disclosure also relates to compositions and methods of irradiating cell population for reducing proliferation.
    Type: Application
    Filed: November 11, 2022
    Publication date: May 4, 2023
    Inventors: Felicia PAGLIUCA, George HARB, Mads GURTLER, Austin THIEL, Jihad YASIN, Evrett THOMPSON
  • SC-BETA CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME
    Publication number: 20230076529
    Abstract: Disclosed herein are methods, compositions, kits, and agents useful for inducing ? cell maturation, and isolated populations of SC-? cells for use in various applications, such as cell therapy.
    Type: Application
    Filed: November 1, 2022
    Publication date: March 9, 2023
    Inventors: Quinn P. Peterson, Felicia J. Pagliuca, Douglas A. Melton, Jeffrey Robert Millman, Michael Saris Segel, Mads Gurtler
  • SC-BETA CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME
    Publication number: 20220396775
    Abstract: Disclosed herein are methods, compositions, kits, and agents useful for inducing ? cell maturation, and isolated populations of SC-? cells for use in various applications, such as cell therapy.
    Type: Application
    Filed: February 11, 2022
    Publication date: December 15, 2022
    Inventors: Quinn P. Peterson, Felicia J. Pagliuca, Douglas A. Melton, Jeffrey Robert Millman, Michael Saris Segel, Mads Gurtler
  • METHODS FOR GENERATING STEM CELL-DERIVED BETA CELLS AND METHODS OF USE THEREOF
    Publication number: 20220177850
    Abstract: Disclosed herein are methods for generating SC-? cells, and isolated populations of SC-? cells for use in various applications, such as cell therapy.
    Type: Application
    Filed: October 15, 2021
    Publication date: June 9, 2022
    Inventors: Douglas A. Melton, Mads Gurtler
  • SC-BETA CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME
    Publication number: 20220162562
    Abstract: Disclosed herein are methods, compositions, kits, and agents useful for inducing ? cell maturation, and isolated populations of SC-? cells for use in various applications, such as cell therapy.
    Type: Application
    Filed: October 29, 2021
    Publication date: May 26, 2022
    Inventors: Quinn P. Peterson, Felicia J. Pagliuca, Douglas A. Melton, Jeffrey R. Millman, Michael Saris Segel, Mads Gurtler
  • SC-beta cells and compositions and methods for generating the same
    Patent number: 11162078
    Abstract: Disclosed herein are methods, compositions, kits, and agents useful for inducing ? cell maturation, and isolated populations of SC-? cells for use in various applications, such as cell therapy.
    Type: Grant
    Filed: July 21, 2020
    Date of Patent: November 2, 2021
    Assignee: President and Fellows of Harvard College
    Inventors: Quinn P. Peterson, Felicia J. Pagliuca, Douglas A. Melton, Jeffrey R. Millman, Michael Saris Segel, Mads Gurtler
  • Methods for generating stem cell-derived beta cells and methods of use thereof
    Patent number: 11155787
    Abstract: Disclosed herein are methods for generating SC-? cells, and isolated populations of SC-? cells for use in various applications, such as cell therapy.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: October 26, 2021
    Assignee: President and Fellows of Harvard College
    Inventors: Douglas A. Melton, Mads Gurtler
  • SC-beta cells and compositions and methods for generating the same
    Patent number: 11104883
    Abstract: Disclosed herein are methods, compositions, kits, and agents useful for inducing ? cell maturation, and isolated populations of SC-? cells for use in various applications, such as cell therapy.
    Type: Grant
    Filed: July 21, 2020
    Date of Patent: August 31, 2021
    Assignee: President and Fellows of Harvard College
    Inventors: Quinn P. Peterson, Felicia J. Pagliuca, Douglas A. Melton, Jeffrey R. Millman, Michael Saris Segel, Mads Gurtler
  • Serum-free in vitro directed differentiation protocol for generating stem cell-derived beta cells and uses thereof
    Patent number: 11085026
    Abstract: Disclosed herein are methods for generating SC-? cells using chemically defined, completely serum free media, and isolated populations of SC-? cells for use in various applications, such as cell therapy.
    Type: Grant
    Filed: July 21, 2020
    Date of Patent: August 10, 2021
    Assignee: President and Fellows of Harvard College
    Inventors: Douglas A. Melton, Mads Gurtler
  • Serum-free in vitro directed differentiation protocol for generating stem cell-derived beta cells and uses thereof
    Patent number: 11085025
    Abstract: Disclosed herein are methods for generating SC-? cells using chemically defined, completely serum free media, and isolated populations of SC-? cells for use in various applications, such as cell therapy.
    Type: Grant
    Filed: July 21, 2020
    Date of Patent: August 10, 2021
    Assignee: President and Fellows of Harvard College
    Inventors: Douglas A. Melton, Mads Gurtler
  • Serum-free in vitro directed differentiation protocol for generating stem cell-derived beta cells and uses thereof
    Patent number: 11085027
    Abstract: Disclosed herein are methods for generating SC-? cells using chemically defined, completely serum free media, and isolated populations of SC-? cells for use in various applications, such as cell therapy.
    Type: Grant
    Filed: July 21, 2020
    Date of Patent: August 10, 2021
    Assignee: President and Fellows of Harvard College
    Inventors: Douglas A. Melton, Mads Gurtler
  • SC-beta cells and compositions and methods for generating the same
    Patent number: 11078463
    Abstract: Disclosed herein are methods, compositions, kits, and agents useful for inducing ? cell maturation, and isolated populations of SC-? cells for use in various applications, such as cell therapy.
    Type: Grant
    Filed: July 21, 2020
    Date of Patent: August 3, 2021
    Assignee: President and Fellows of Harvard College
    Inventors: Quinn P. Peterson, Felicia J. Pagliuca, Douglas A. Melton, Jeffrey R. Millman, Michael Saris Segel, Mads Gurtler
  • METHODS OF ENHANCING STEM CELL DIFFERENTIATION INTO BETA CELLS
    Publication number: 20210198632
    Abstract: Disclosed herein are compositions and methods of enhancing stem cell differentiation into beta cells with use of one or more epigenetic modification compounds. The present disclosure also relates to compositions and methods of sorting and enriching the differentiated beta cells. The present disclosure also relates to compositions and methods of irradiating cell population for reducing proliferation.
    Type: Application
    Filed: September 2, 2020
    Publication date: July 1, 2021
    Inventors: Felicia Pagliuca, George Harb, Mads Gurtler, Jason Gaglia, Yeh-Chuin Poh, Lillian Ye, Austin Thiel, Jihad Yasin, Evrett Thompson
  • SC-BETA CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME
    Publication number: 20210079355
    Abstract: Disclosed herein are methods, compositions, kits, and agents useful for inducing ? cell maturation, and isolated populations of SC-? cells for use in various applications, such as cell therapy.
    Type: Application
    Filed: July 21, 2020
    Publication date: March 18, 2021
    Inventors: Quinn P. Peterson, Felicia J. Pagliuca, Douglas A. Melton, Jeffrey R. Millman, Michael Saris Segel, Mads Gurtler
  • SC-BETA CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME
    Publication number: 20200385681
    Abstract: Disclosed herein are methods, compositions, kits, and agents useful for inducing ? cell maturation, and isolated populations of SC-? cells for use in various applications, such as cell therapy.
    Type: Application
    Filed: July 21, 2020
    Publication date: December 10, 2020
    Applicant: President and Fellows of Harvard College
    Inventors: Quinn P. Peterson, Felicia J. Pagliuca, Douglas A. Melton, Jeffrey R. Millman, Michael Saris Segel, Mads Gurtler