Abstract: A system for measuring synchrony between two or more regions, or within a single region, of a subject's brain. The system can include a signal conditioning module in communication with a phase extraction module. The signal conditioning module can receive an oscillating signal, bandpass filter the signal, and convert the signal to its real and imaginary components. The phase extraction module can receive the real and imaginary components, determine the quadrant of the oscillating signal on the complex plane based on the real and imaginary components, and determine the phase of the oscillating signal using a linear arctangent approximation based on the determined quadrant. The system can calculate synchrony metrics based on the determined phase.

Abstract: A method for controlling connectivity between two or more brain regions of a subject includes receiving signals corresponding to a connectivity between two or more regions of a subject's brain, measuring a connectivity level from the signals, and delivering at least one stimulation pulse to at least one target region of the subject's brain if the measured connectivity level is outside of a predetermined range.

Abstract: Methods, systems, and devices are disclosed for an efficient hardware architecture to implement gradient boosted trees for detecting biological conditions. For example, a method of detecting a biological condition includes receiving, by a device, a plurality of physiological signals from a plurality of input channels of the device, selecting, based on a trained prediction model, one or more input channels from the plurality of input channels, converting the one or more physiological signals received from the one or more input channels to one or more digital physiological signals, identifying, by using the plurality of gradient boosted decision trees, the selected characteristic in the one or more digital physiological signals, and determining a presence of a physiological condition based on an addition of the output values obtained from the plurality of gradient boosted decision trees.

Abstract: Methods, systems, and devices are disclosed for an efficient hardware architecture to implement gradient boosted trees for detecting biological conditions. For example, a method of detecting a biological condition includes receiving, by a device, a plurality of physiological signals from a plurality of input channels of the device, selecting, based on a trained prediction model, one or more input channels from the plurality of input channels, converting the one or more physiological signals received from the one or more input channels to one or more digital physiological signals, identifying, by using the plurality of gradient boosted decision trees, the selected characteristic in the one or more digital physiological signals, and determining a presence of a physiological condition based on an addition of the output values obtained from the plurality of gradient boosted decision trees.

Abstract: Disclosed are low power electronic devices configured to exploit the sub-threshold swing, unidirectional tunneling, and low-voltage operation of steep slope-tunnel tunnel field-effect transistors (TFET) to improve power-conversion efficiency and power-efficiency of electrical systems incorporating the TFET as an electrical component to perform energy harvesting, signal processing, and related operations. The devices include a HTFET-based rectifier having various topologies, a HTFET-based DC-DC charge pump converter, a HTFET-based amplifier having an amplifier circuit including a telescopic operational transconductance amplifier, and a HTFET-based SAR A/D converter having a HTFET-based transmission gate DFF. Any one of the devices may be used to generate a RF-powered system with improved power conversion efficiencies of power harvesters and power efficiencies of processing components within the system.

Abstract: The present invention relates to a method for compressing signal data of a plurality of biological signals captured by a plurality of implanted measurement devices. The present invention further relates to an implantable sensor configured to carry out said method of compression. The present invention also concerns a method for recovering the plurality of biological signals from the compressed data as well as a system including a plurality of implantable sensors, a transmitter, a receiver and a processor configured to recover the plurality of biological signals from the compressed data.

Abstract: Disclosed are low power electronic devices configured to exploit the sub-threshold swing, unidirectional tunneling, and low-voltage operation of steep slope-tunnel tunnel field-effect transistors (TFET) to improve power-conversion efficiency and power-efficiency of electrical systems incorporating the TFET as an electrical component to perform energy harvesting, signal processing, and related operations. The devices include a HTFET-based rectifier having various topologies, a HTFET-based DC-DC charge pump converter, a HTFET-based amplifier having an amplifier circuit including a telescopic operational transconductance amplifier, and a HTFET-based SAR A/D converter having a HTFET-based transmission gate DFF. Any one of the devices may be used to generate a RF-powered system with improved power conversion efficiencies of power harvesters and power efficiencies of processing components within the system.