Abstract: An objective of the present invention is to provide a steel sheet having a high strength which can provide excellent appearance quality. The steel sheet has a chemical composition including, in mass %, C: more than 0.030% to 0.145%, Si: 0% to 0.500%, Mn: 0.50% to 2.50%, P: 0% to 0.100%, S: 0% to 0.020%, Al: 0% to 1.000% or less, N: 0% to 0.0100%, and the like, wherein a metal micro-structures consisting of 70 to 95% of ferrite in volume fraction and 5 to 30% of hard phases in volume fraction, and a value X1 obtained by dividing a standard deviation of average Mn concentrations in a rolling direction at ¼ sheet-thickness positions in a sheet thickness direction by an average Mn concentration at the ¼ sheet-thickness positions is 0.025 or less.

Abstract: A tire vulcanization mold includes a molding surface for molding a tire during vulcanization molding. The molding surface can include a first region in which a plurality of recesses for forming a plurality of projections on a surface of the tire can be provided. In the first region, at least two of the recesses can be arranged per mm2. Each of the recesses can include a side wall surface, a bottom surface, and a virtual recess central axis extending in a depth direction of the recess. In a cross-sectional view of the recess including the recess central axis, the bottom surface can include a bottom projection projecting outward in the depth direction, and the side wall surface can include an arc-shaped surface smoothly connected to the bottom surface.

Abstract: A tire vulcanization mold includes a molding surface for molding a tire during vulcanization molding. The molding surface can include a first region in which a plurality of recesses for forming a plurality of projections on a surface of the tire can be provided. In the first region, at least two of the recesses can be arranged per mm2. Each of the recesses can include a side wall surface, a bottom surface, and a virtual recess central axis extending in a depth direction of the recess. In a cross-sectional view of the recess including the recess central axis, the bottom surface can include a bottom projection projecting outward in the depth direction, and the side wall surface can include an arc-shaped surface smoothly connected to the bottom surface.

Abstract: Disclosed is a compound represented by formula (1): wherein A1 represents N(O)p or CH; A2 represents N(O)q; R1 represents a trifluoromethyl group, a halogen atom or a hydrogen atom; R2 represents a C1-C3 perfluoroalkyl group, p represents 0 or 1; q represents 0 or 1; n represents 0, 1 or 2; and m represents 0, 1 or 2, having an excellent controlling effect on pests.

Abstract: A fused heterocyclic compound represented by formula (1) or an N-oxide thereof has an excellent control effect on pests: wherein A1 represents N or the like, A2 represents NR6 or the like, A3 represents CR12 or the like, R1 represents a C1 to C6 chain hydrocarbon group or the like, R2, R4 and R5 are the same or different and represent a C1 to C3 alkyl group optionally having one or more halogen atoms or the like, R3 represents a C1 to C6 chain hydrocarbon group or the like, R6 represents a C1 to C6 chain hydrocarbon group or the like, any one set of R9 and R10, R10 and R11, and R11 and R12 in R9, R10, R11 and R12, together with the carbon atoms to which they are bound, forms a ring, and n represents 0, 1 or 2.

Abstract: There is provided a compound having an excellent controlling effect on pests represented by the formula (1): wherein, A1 represents —NR7—, etc., A2 represents a nitrogen atom, etc., A3 represents a nitrogen atom, etc., R1 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R2, R3 and R4 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more halogen atoms, etc., R5 and R6 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R7 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group W, etc., n represents 0, 1 or 2, or an N-oxide thereof.

Abstract: Fused heterocyclic compounds of formula (1): (G1 and G2 represent a nitrogen atom or the like, A1 and A2 represent a nitrogen atom or the like, A3 represents —NR8— or the like, A4 and A5 represent a nitrogen atom or the like, R1 represents a C1-C6 chain hydrocarbon group or the like optionally having one or more atoms or groups selected from a group X, R2 and R3 are the same or different and represent a C1-C6 chain hydrocarbon group or the like optionally having one or more atoms or groups selected from the group X, R8 represents a C1-C6 chain hydrocarbon group or the like optionally having one or more atoms or groups selected from a group W, and n represents 0, 1 or 2), or N-oxides thereof are described. The disclosed compounds are very effective for pest control.

Abstract: There is provided a compound having an excellent controlling effect on pests represented by the formula (1): wherein, A1 represents —NR7—, etc., A2 represents a nitrogen atom, etc., A3 represents a nitrogen atom, etc., R1 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R2, R3 and R4 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more halogen atoms, etc., R5 and R6 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R7 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group W, etc., n represents 0, 1 or 2, or an N-oxide thereof.

Abstract: There is provided a compound having an excellent controlling effect on pests represented by the formula (1): wherein, A1 represents —NR7—, etc., A2 represents a nitrogen atom, etc., A3 represents a nitrogen atom, etc., R1 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R2, R3 and R4 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more halogen atoms, etc., R5 and R6 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R7 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group W, etc., n represents 0, 1 or 2, or an N-oxide thereof.

Abstract: The fused heterocyclic compound represented by formula (1) has excellent effectiveness in pest control. In the formula (1), J represents formula J1, J2, J3, J4, J5 or J6; A1; A2; A3; A4; A5; B1; B2; B4; B5; and B6 each represent a nitrogen atom, etc.; B3 represents NR15, etc.; R1 represents a C1-C6 chain hydrocarbon group, etc., optionally substituted with one or more atoms or groups selected from group X; the pairs R2 and R3 and R5 and R6 are the same or different, and represent a C1-C6 chain hydrocarbon group, etc., optionally substituted with one or more atoms or groups selected from group X; R4 represents a C1-C6 chain hydrocarbon group, etc., optionally substituted with one or more atoms or groups selected from group W; and n represents 0, 1, or 2.

Abstract: The fused heterocyclic compound represented by formula (1) has excellent effectiveness in pest control. In the formula (1), J represents formula J1, J2, J3, J4, J5 or J6; A1; A2; A3; A4; A5; B1; B2; B4; B5; and B6 each represent a nitrogen atom, etc.; B3 represents NR15, etc.; R1 represents a C1-C6 chain hydrocarbon group, etc., optionally substituted with one or more atoms or groups selected from group X; the pairs R2 and R3 and R5 and R6 are the same or different, and represent a C1-C6 chain hydrocarbon group, etc., optionally substituted with one or more atoms or groups selected from group X; R4 represents a C1-C6 chain hydrocarbon group, etc., optionally substituted with one or more atoms or groups selected from group W; and n represents 0, 1, or 2.

Abstract: A fused heterocyclic compound the formula (1): wherein A1 represents —NR8—, and the like; A2 represents a nitrogen atom, and the like; A3 represents a nitrogen atom, and the like; R1 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R2, R3, R4, and R5 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, and the like; R6 and R7 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R8 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group W, and the like; n represents 0, 1 or 2. The compound has an excellent activity of controlling pests.

Abstract: The fused heterocyclic compound represented by formula (1), or an N-oxide thereof, has excellent effectiveness in pest control. In the formula G1 represents a nitrogen atom, etc.; G2 represents a nitrogen atom, etc.; A1 represents a nitrogen atom, etc.; A2 represents a nitrogen atom, etc.; A3 represents a nitrogen atom, etc.; A4 represents a nitrogen atom, etc.; A5 represents a nitrogen atom, etc.; R1 represents a C1-C6 chain hydrocarbon group, etc., optionally having one or more atoms or groups selected from group X; R2, R3 and R4 are the same or different, and represent a C1-C6 chain hydrocarbon group, etc., optionally having one or more atoms or groups selected from group X; R5 and R6 are the same or different, and represent a C1-C6 chain hydrocarbon group, etc., optionally having one or more atoms or groups selected from group X; and n represents 0, 1, 2.

Abstract: The fused heterocyclic compound represented by formula (1) has excellent effectiveness in pest control. In the formula (1), J represents formula J1, J2, J3, J4, J5 or J6; A1; A2; A3; A4; A5; B1; B2; B4; B5; and B6 each represent a nitrogen atom, etc.; B3 represents NR5, etc.; R1 represents a C1-C6 chain hydrocarbon group, etc., optionally having one or more atoms or groups selected from group X; the pairs R2 and R3 and R5 and R6 are the same or different, and represent a C1-C6 chain hydrocarbon group, etc., optionally having one or more atoms or groups selected from group X; R4 represents a C1-C6 chain hydrocarbon group, etc., optionally having one or more atoms or groups selected from group W; and n represents 0, 1, or 2.

Abstract: There is provided a compound having an excellent controlling effect on pests represented by the formula (1): wherein, A1 represents —NR7—, etc., A2 represents a nitrogen atom, etc., A3 represents a nitrogen atom, etc., R1 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R2, R3 and R4 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more halogen atoms, etc., R5 and R6 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R7 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group W, etc., n represents 0, 1 or 2, or an N-oxide thereof.

Abstract: A fused heterocyclic compound represented by formula (1) or an N-oxide thereof has an excellent control effect on pests: wherein A1 represents N or the like, A2 represents NR6 or the like, A3 represents CR12 or the like, R1 represents a C1 to C6 chain hydrocarbon group or the like, R2, R4 and R5 are the same or different and represent a C1 to C3 alkyl group optionally having one or more halogen atoms or the like, R3 represents a C1 to C6 chain hydrocarbon group or the like, R6 represents a C1 to C6 chain hydrocarbon group or the like, any one set of R9 and R10, R10 and R11, and R11 and R12 in R9, R10, R11 and R12, together with the carbon atoms to which they are bound, forms a ring, and n represents 0, 1 or 2.

Abstract: Fused heterocyclic compounds of formula (1): (G1 and G2 represent a nitrogen atom or the like, A1 and A2 represent a nitrogen atom or the like, A3 represents —NR8— or the like, A4 and A5 represent a nitrogen atom or the like, R1 represents a C1-C6 chain hydrocarbon group or the like optionally having one or more atoms or groups selected from a group X, R2 and R3 are the same or different and represent a C1-C6 chain hydrocarbon group or the like optionally having one or more atoms or groups selected from the group X, R8 represents a C1-C6 chain hydrocarbon group or the like optionally having one or more atoms or groups selected from a group W, and n represents 0, 1 or 2), or N-oxides thereof are described. The disclosed compounds are very effective for pest control.

Abstract: The present invention provides, as an enzyme which can be used for enzyme replacement therapy for Fabry disease, a protein having ?-galactosidase activity, which shows no allergic adverse side effect, shows a high stability in blood, and can be easily incorporated into a cell of an affected organ. The protein of the present invention is a protein which has acquired ?-galactosidase activity by changing the structure of the active site of wild-type human ?-N-acetylgalactosaminidase.

Abstract: Disclosed is a compound represented by formula (1): wherein A1 represents N(O)p or CH; A2 represents N(O)q; R1 represents a trifluoromethyl group, a halogen atom or a hydrogen atom; R2 represents a C1-C3 perfluoroalkyl group, p represents 0 or 1; q represents 0 or 1; n represents 0, 1 or 2; and m represents 0, 1 or 2, having an excellent controlling effect on pests.

Abstract: This fused heterocyclic compound represented in formula (1) has excellent effectiveness in pest control. In the formula, A1 represents —NR4—, etc.; A2 represents a nitrogen atom, etc.; R1 represents an ethyl group, a cyclopropyl group, or a cyclopropylmethyl group; R2 represents —S(O)mR6 or —C(R7)(CF3)2; R4 represents a C1-C6 alkyl group optionally having one or more halogen atoms; R6 represents a C1-C6 haloalkyl group; R7 represents a fluorine atom or a chlorine atom, and m and n each represents 0, 1 or 2.