Patents by Inventor Makio Otsuki

Makio Otsuki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antitumor effect potentiators
    Patent number: 6930115
    Abstract: When used concurrently with an antitumor agent, a compound having a Rho kinase inhibitory activity, such as (R)-(+)-N-(4-pyridyl)-4-(1-aminoethyl)benzamide, reinforces an antitumor effect of the antitumor agent and is useful as an antitumor effect potentiator. Particularly, a compound having a Rho kinase inhibitory activity used with an antitumor agent in combination can reduce the dose of the antitumor agent, which in turn affords provision of a sufficient effect and/or reduction of side effects.
    Type: Grant
    Filed: June 22, 2001
    Date of Patent: August 16, 2005
    Assignee: Mitsubishi Pharma Corporation
    Inventors: Akihiro Fujii, Hiroshi Tanaka, Makio Otsuki, Takafumi Kawaguchi, Kouichi Oshita
  • Antitumor effect potentiators
    Publication number: 20030165576
    Abstract: When used concurrently with an antitumor agent, a compound having a Rho kinase inhibitory activity, such as (R)-(+)-N-(4-pyridyl)-4-(1-aminoethyl)benzamide, reinforces an antitumor effect of the antitumor agent and is useful as an antitumor effect potentiator.
    Type: Application
    Filed: February 5, 2003
    Publication date: September 4, 2003
    Inventors: Akihiro Fujii, Hiroshi Tanaka, Makio Otsuki, Takafumi Kawaguchi, Kouichi Oshita