Patents by Inventor Makoto Gotoh
Makoto Gotoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11948544Abstract: The musical instrument tuner includes: a sensor device that is attached to a musical instrument; and an operation device that is able to perform wireless communication mutually with the sensor device, in which the sensor device includes an acceleration sensor that has at least two detection axes, frequency detection means for detecting, as a detected frequency, a frequency of a vibration of musical sound generated through an operation of the musical instrument based on an output from the acceleration sensor, and sensor-side communication means for transmitting transmission information including information regarding the detected frequency to the operation device, and the operation device includes operation-side communication means for receiving the transmission information transmitted from the sensor device, display means, and control means for generating tuning information of the musical instrument and causing the display means to display the tuning information based on the transmission information receivedType: GrantFiled: July 29, 2021Date of Patent: April 2, 2024Assignees: GOTOH GUT CO., LTD., GUNMA PREFECTUREInventors: Atsushi Kajihara, Masaki Gotoh, Hiroshi Miyajima, Osamu Niijima, Yuta Uchiumi, Makoto Matsumoto, Kento Suzuki
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Patent number: 9527836Abstract: An object is to provide a crystal having a new crystal habit of luliconazole and expand the possibility of application to pharmaceuticals. Disclosed is a crystal of luliconazole having such a crystal habit that (020) plane is a specific crystal growth surface.Type: GrantFiled: April 11, 2014Date of Patent: December 27, 2016Assignees: POLA PHARMA INC., NIHON NOHYAKU CO., LTD.Inventors: Takaaki Masuda, Makoto Gotoh, Hideo Kaneda
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Publication number: 20160168136Abstract: An object is to provide a crystal having a new crystal habit of luliconazole and expand the possibility of application to pharmaceuticals. Disclosed is a crystal of luliconazole having such a crystal habit that (020) plane is a specific crystal growth surface.Type: ApplicationFiled: April 11, 2014Publication date: June 16, 2016Inventors: Takaaki Masuda, Makoto Gotoh, Hideo Kaneda
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Publication number: 20150366845Abstract: An object is to provide means for precisely treating pneumonia caused by intracellular parasite, protozoa, and/or fungus. A pharmaceutical composition for pneumonia, comprising a compound represented by the following general formula (1) as an active ingredient: (In the formula, R represents a halogen atom or a hydrogen atom, and X represents a halogen atom.Type: ApplicationFiled: December 27, 2013Publication date: December 24, 2015Applicants: POLA PHARMA INC.,, NIHON NOHYAKU CO., LTD.,Inventors: Tsuyoshi Shimamura, Yoshiyuki Miyata, Makoto Gotoh
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Publication number: 20150352078Abstract: An object is to provide means for precisely treating vaginitis caused by intracellular parasite, protozoa, and/or fungus. A pharmaceutical composition for vaginitis, comprising a compound represented by the following general formula (1) as an active ingredient: (1) (In the formula, R represents a halogen atom or a hydrogen atom, and X represents a halogen atom.Type: ApplicationFiled: December 27, 2013Publication date: December 10, 2015Inventors: Tsuyoshi Shimamura, Yoshiyuki Miyata, Makoto Gotoh
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Patent number: 9012484Abstract: An object is to provide means for improving the solubility of luliconazole. Disclosed is a crystal consisting of luliconazole and short chain alcohol having a number of carbon atom or atoms of 1 to 4.Type: GrantFiled: September 6, 2013Date of Patent: April 21, 2015Assignees: Pola Pharma Inc., Nihon Nohyaku Co., Ltd.Inventors: Takaaki Masuda, Makoto Gotoh, Yoshiyuki Miyata
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Publication number: 20140080882Abstract: An object is to provide means for improving the solubility of luliconazole. Disclosed is a crystal consisting of luliconazole and short chain alcohol having a number of carbon atom or atoms of 1 to 4.Type: ApplicationFiled: September 6, 2013Publication date: March 20, 2014Applicants: Nihon Nohyaku Co., Ltd., Pola Pharma Inc.Inventors: Takaaki Masuda, Makoto Gotoh, Yoshiyuki Miyata
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Patent number: 6875768Abstract: Heterocyclic amine derivatives represented by general formula (I): wherein R1, R2 and R3 represent each H, optionally halogenated C3-6 cycloalkyl, etc.; Q represents an optionally substituted heterocycle containing O, S or N; X represents halogeno, cyano, halo(C1-6)alkyl, etc.; n is from 1 to 4; and Z1 and Z2 represent each O or S; and intermediates thereof represented by the following general formula (IV?): Q?—NH2 wherein Q? represents a definite heterocycle selected from among those represented by Q. Agricultural/horticultural insecticides having a remarkable effect of controlling pest insects of crops such as rice, fruit trees and vegetables, as well as various agricultural, forestry, horticultural and stored grain pest insects.Type: GrantFiled: July 4, 2000Date of Patent: April 5, 2005Assignee: Nihon Nohyako Co., Ltd.Inventors: Kouzou Machiya, Kazuyoshi Endoh, Takashi Furuya, Hayami Nakao, Makoto Gotoh, Eiji Kohno, Masanori Tohnishi, Kazuyuki Sakata, Masayuki Morimoto, Akira Seo
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Patent number: 6806275Abstract: The present invention provides an arylpiperidine derivative of the formula (I) or a pharmaceutically acceptable salt thereof, which has antipsychotic effect: wherein D is a carbon atom or a nitrogen atom, E is a CH group or a nitrogen atom, G is an oxygen atom, a sulfur atom, a nitrogen atom or an NH group, Y1 is a hydrogen atom or a halogen atom, n is an integer of 1 to 4, and R1 is a group represented by any of the formulas (i) to (iv) defined in the specification.Type: GrantFiled: April 12, 2002Date of Patent: October 19, 2004Assignees: Nihon Nohyaku Co., Ltd., Taisho Pharmaceutical Co., Ltd.Inventors: Masashi Nagamine, Makoto Gotoh, Masanori Yoshida, Atsuro Nakazato, Toshihito Kumagai, Shigeyuki Chaki, Kazuyuki Tomisawa
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Patent number: 6747041Abstract: Heterocyclic dicarboxylic acid diamide derivative represented by the general formula (I): wherein R1, R2 and R3 represent each H, optionally halogenated C3-6 cycloalkyl, etc.; Het represents a 5- or 6-membered heterocycle; X and Y represent each halocyano, nitro, optionally halogenated C3-6, cycloalkyl, optionally substituted phenyl, an optionally substituted heterocycle, etc; n is from 0 to 3; m is from 1 to 5; Z1 and Z2 represent each O or S; and B1 to B4 represent each C or N. Agricultural/horticultural insecticides having an excellent controlling effect on pest insects such as diamond-back moth (Pluntella xylostella) and tobacco cutworm (Spodoptera litura).Type: GrantFiled: April 10, 2002Date of Patent: June 8, 2004Assignee: Nihon Nohyaku Co., Ltd.Inventors: Takeshi Katsuhira, Takashi Furuya, Makoto Gotoh, Masanori Tohnishi, Hideo Takaishi, Kazuyuki Sakata, Masayuki Morimoto, Akira Seo
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Publication number: 20020156283Abstract: The present invention provides an arylpiperidine derivative of the formula (I) or a pharmaceutically acceptable salt thereof, which has antipsychotic effect: 1Type: ApplicationFiled: April 12, 2002Publication date: October 24, 2002Inventors: Masashi Nagamine, Makoto Gotoh, Masanori Yoshida, Atsuro Nakazato, Toshihito Kumagai, Shigeyuki Chaki, Kazuyuki Tomisawa
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Patent number: 6469003Abstract: A pyridazinone derivative represented by formula (I): a pharmaceutically acceptable salt thereof, or a derivative thereof, or a pharmaceutical composition comprising as an active ingredient the derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier or diluent.Type: GrantFiled: February 14, 2001Date of Patent: October 22, 2002Assignee: Nihon Nohyaku Co., Ltd.Inventors: Makoto Gotoh, Koji Umimoto, Masanobu Onishi, Akiyuki Satoh, Yoshitami Oshita, Masashi Nagamine
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Patent number: 6407121Abstract: The present invention provides an arylpiperidine derivative of the formula (I) or a pharmaceutically acceptable salt thereof, which has antipsychotic effect: wherein D is a carbon atom or a nitrogen atom, E is a CH group or a nitrogen atom, G is an oxygen atom, a sulfur atom, a nitrogen atom or an NH group, Y1 is a hydrogen atom or a halogen atom, n is an integer of 1 to 4, and R1 is a group represented by any of the formulas (i) to (iv) defined in the specification.Type: GrantFiled: September 13, 2000Date of Patent: June 18, 2002Assignees: Nihon Nohyaku Co., Ltd., Taisho Pharmaceutical Co., Ltd.Inventors: Masashi Nagamine, Makoto Gotoh, Masanori Yoshida, Atsuro Nakazato, Toshihito Kumagai, Shigeyuki Chaki, Kazuyuki Tomisawa
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Patent number: 6380384Abstract: A 1,2-dihydro-2-oxoquinoline derivative represented by the formula: wherein Ar is a pyridyl group or a group represented by the formula: (wherein X3 and X4 are the same or different, and are each a hydrogen atom, a halogen atom, a C1-5 alkyl group, a C1-5 alkoxy group, a hydroxyl group or a trifluoromethyl group), Y is a nitrogen atom, CH or C(OH), R1 and R2 are the same or different, and are each a hydrogen atom, a C1-10 alkyl group, a C3-15 alkoxyalkyl group or a C3-15 alkylaminoalkyl group, or R1 and R2 taken together with the nitrogen atom to which they are attached form a cyclic amino group, X1 and X2 are the same or different, and are each a hydrogen atom, a C1-5 alkyl group, a C1-5 alkoxy group or a halogen atom; or X1 and X2 taken together form an alkylenedioxy group, and n is an integer of 1 to 3; or a pharmaceutically acceptable salt thereof.Type: GrantFiled: April 10, 2001Date of Patent: April 30, 2002Assignees: Taisho Pharmaceutical Co., Ltd., Nihon Nohyaku Co., Ltd.Inventors: Atsuro Nakazato, Taketoshi Okubo, Toshihito Kumagai, Shigeyuki Chaki, Kazuyuki Tomisawa, Masashi Nagamine, Makoto Gotoh, Masanori Yoshida
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Publication number: 20020049323Abstract: A 1,2-dihydro-2-oxoquinoline derivative represented by the formula: 1Type: ApplicationFiled: April 10, 2001Publication date: April 25, 2002Inventors: Atsuro Nakazato, Taketoshi Okubo, Toshihito Kumagai, Shigeyuki Chaki, Kazuyuki Tomisawa, Masashi Nagamine, Makoto Gotoh, Masanori Yoshida
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Patent number: 6329525Abstract: A 1,2-dihydro-2-oxoquinoline derivative represented by the formula: wherein Ar is a pyridyl group or a group represented by the formula: (wherein X3 and X4 are the same or different, and are each a hydrogen atom, a halogen atom, a C1-5 alkyl group, a C1-5 alkoxy group, a hydroxyl group or a trifluoromethyl group), Y is a nitrogen atom, CH or C(OH), R1 and R2 are the same or different, and are each a hydrogen atom, a C1-10 alkyl group, a C3-15 alkoxyalkyl group or a C3-15 alkylaminoalkyl group, or R1 and R2 taken together with the nitrogen atom to which they are attached form a cyclic amino group, X1 and X2 are the same or different, and are each a hydrogen atom, a C1-5 alkyl group, a C1-5 alkoxy group or a halogen atom, or X1 and X2 taken together form an alkylenedioxy group, and n is an integer of 1 to 3; or a pharmaceutically acceptable salt thereof.Type: GrantFiled: June 1, 2000Date of Patent: December 11, 2001Assignees: Taisho Pharmaceutical Co., Ltd., Nihon Nohyaku Co., Ltd.Inventors: Atsuro Nakazato, Taketoshi Okubo, Toshihito Kumagai, Shigeyuki Chaki, Kazuyuki Tomisawa, Masashi Nagamine, Makoto Gotoh, Masanori Yoshida
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Patent number: 6291467Abstract: An aromaheterocyclic derivative represented by the formula: wherein Z is a group represented by the following formula: wherein Ar1 is a phenyl group or a phenyl group substituted with a halogen atom or an alkyl group of 1 to 5 carbon atoms, R2 is an alkyl group of 1 to 5 carbon atoms, Y is a hydrogen atom, a mercapto group, an alkylthio group of 1 to 5 carbon atoms, an amino group or an amino group substituted with one or two alkyl groups having 1 to 5 carbon atoms, Ar2 is a phenyl group of one or two substituents selected from the group consisting of a halogen atom, an alkyl group of 1 to 5 carbon atoms, an alkoxy group of 1 to 5 carbon atoms, a hydroxyl group and a trifluoromethyl group, or a phenyl group, B1-B2 is CH—CO or C═C(R1) (wherein R1 is a hydrogen atom or an alkyl group of 1 to 5 carbon atoms), and n is an integer of 1 to 4, or a pharmaceutically acceptable salt thereof, which is a dopamine D4 receptor antagonist compound having an antipsychotic actioType: GrantFiled: September 15, 2000Date of Patent: September 18, 2001Assignees: Taisho Pharmaceutical Co., Ltd., Nihon Nohyaku Co. Ltd.Inventors: Atsuro Nakazato, Toshihito Kumagai, Shigeyuki Chaki, Kazuyuki Tomisawa, Masashi Nagamine, Makoto Gotoh, Masanori Yoshida
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Patent number: 6281355Abstract: A nitrogen-containing tetracyclic compound represented by the formula: wherein Y1—Y2—Y3 is N—C═N or a group represented by the formula: C═C—NR3 (wherein R3 is a hydrogen atom, a C1-5 alkyl group or a nitrogen-containing C2-10 alkyl group), Y4 is S, SO, SO2, CH2 or a group represented by the formula: NR4 (wherein R4 is a C1-5 alkanoyl group or a C1-5 alkyl group), R1 and R2 are the same or different, and are each a hydrogen atom, a C1-10 alkyl group, a C3-15 alkoxyalkyl group or a C3-15 alkylaminoalkyl group, or R1 and R2 taken together with the nitrogen atom to which they are attached form a cyclic amino group, X1 and X2 are the same or different, and are each a hydrogen atom, a C1-5 alkyl group, a C1-5 alkoxy group or a halogen atom, and n is 0, 1 or 2; or a pharmaceutically acceptable salt thereof.Type: GrantFiled: June 1, 2000Date of Patent: August 28, 2001Assignees: Taisho Pharmaceutical Co., Ltd., Nihon Nohyaku Co., Ltd.Inventors: Atsuro Nakazato, Taketoshi Okubo, Toshihito Kumagai, Shigeyuki Chaki, Kazuyuki Tomisawa, Masashi Nagamine, Makoto Gotoh, Kuniaki Kondoh, Masanori Yoshida
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Patent number: 6166033Abstract: This invention provides a 2-carbonylthiazole derivative represented by formula (I): ##STR1## wherein each of Ar.sup.1 and Ar.sup.2 represents a phenyl group or a substituted phenyl group; R.sup.1 represents an alkoxy group having 1 to 5 carbon atoms, a hydroxyl group or an amino group; Y.sup.1 --Y.sup.2 represents CH--CO or C.dbd.CR.sup.2, wherein R.sup.2 represents a hydrogen atom or an alkyl group having 1 to 5 carbon atoms; and n is an integer of from 1 to 4, or a pharmaceutically acceptable salt thereof. The disclosed compounds are useful as drugs for preventing and treating dopamine D receptor-related morbid states such as schizophrenia and problematic behavior caused by cerebrovascular accidents and senile dementia and do not induce extrapyramidal disorders as side effects.Type: GrantFiled: November 5, 1999Date of Patent: December 26, 2000Assignees: Taisho Pharmaceutical Co., Ltd., Nihon Nohyaku Co., Ltd.Inventors: Atsuro Nakazato, Toshihito Kumagai, Shigeyuki Chaki, Kazuyuki Tomisawa, Masashi Nagamine, Makoto Gotoh, Masanori Yoshida
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Patent number: 5362325Abstract: A material processing apparatus includes a plurality of syringes provided detachable on a base member and containing fluids that are used for processing a material; A processing chamber is provided detachable on the base member for causing the material processing: An actuation mechanism actuates the plurality of syringes to supply the fluids in the syringes to the processing chamber; An interconnection fixture connects the plurality of syringes to the processing chamber for transporting the fluids in the plurality of syringes to the processing chamber. The plurality of syringes are provided detachable with respect to the interconnection fixture, and the processing chamber is provided detachable with respect to the interconnection fixture.Type: GrantFiled: December 23, 1993Date of Patent: November 8, 1994Assignee: Fujitsu LimitedInventors: Atsushi Shiraishi, Koji Asano, Makoto Gotoh, Kotaro Oka